William J Chiang

US Patent:

20040072282, Apr 15, 2004

Filed:

Jun 23, 2003

Appl. No.:

10/602265

Inventors:

Frank Guarnieri - Princeton NJ, US
John Kulp - Princeton NJ, US
William Chiang - Princeton NJ, US

Assignee:

Sarnoff Corporation

International Classification:

C12P021/06
C07K014/47

US Classification:

435/068100, 530/403000

Abstract:

Methods for chemical ligation and synthesis of peptides and polypeptides including membrane polypeptides and hydrophobic peptides and polypeptides or membrane polypeptide domains in a multiphase solvent mixture comprising at least two component solvents; compositions produced using these methods and assays performed using these compositions.

US Patent:

63261499, Dec 4, 2001

Filed:

Nov 2, 1999

Appl. No.:

9/432745

Inventors:

Zyi Gerald Loewy - Fair Lawn NJ
William Chiang - Monmouth Junction NJ
Hoi Cheong Sun - Dayton NJ
Bryan Lloyd Bentz - Princeton NJ

Assignee:

Sarnoff Corporation - Princeton NJ

International Classification:

C12Q 168
B05D 104
B05D 112
H05C 100

US Classification:

435 6

Abstract:

Provided is a method of fabricating a substrate having on a surface thereof two or more spatially-resolved regions, each with a defined amount or concentration of one of one or more chemical components, the method comprising: associating a chemical component with particles of 1. mu. m to 500. mu. m diameter; electrostatically depositing the particles on the appropriate regions; and if a said spatially-resolved region is to receive a second chemical component, repeating steps (a) and (b) for that chemical component and the appropriate regions.

US Patent:

48883964, Dec 19, 1989

Filed:

Jun 8, 1988

Appl. No.:

7/203835

Inventors:

Herbert K. Reimschuessel - Morristown NJ
William G. Chiang - Fayetteville NY
George J. W. Tichenor - Fayetteville NY

Assignee:

Polypure, Inc. - Solvay NY

International Classification:

C08F 830

US Classification:

525379

Abstract:

Novel cationic polymers are provided by reaction of high molecular weight polymers and copolymers of acrylamide with an alkyl epoxide compound such as glycidyldialkylamine or glycidyltrialkylammonium salt to form polymer chain units containing e. g. pendant (N-2-hydroxypropyl) dialkylamine groups of their trialkylammonium salts. Processes for making the graft copolymers are provided in which the reaction is carried out while maintaining the reaction mixture in gel form by swelling the starting solid polymer with a solvent mixture. The reaction may be carried out in a homogeneous reaction environment or in a heterogeneous reaction environment by dispersing the starting solid polymer in an inert liquid that is a non-solvent for both the polymer and the salt. The polymeric products of the reaction may be hardened with a suitable liquid, such as isopropanol, to a solid particulate material.

US Patent:

58463968, Dec 8, 1998

Filed:

Nov 9, 1995

Appl. No.:

8/556036

Inventors:

Peter John Zanzucchi - West Windsor Township, Mercer County NJ
Satyam Choudary Cherukuri - Cranbury NJ
Sterling Edward McBride - Lawrence Township, Mercer County NJ
Robert R. Demers - Cranbury NJ
Aaron W. Levine - Lawrenceville NJ
Barry Jay Thaler - Lawrenceville NJ
Robert Leon Quinn - Trenton NJ
Paul Leonard Braun - Highland Park NJ
William Chiang - Monmouth Junction NJ
Zhonghui Hugh Fan - Plainsboro NJ
Steven A. Lipp - Cranbury NJ
James R. Matey - Mercerville NJ

Assignee:

Sarnoff Corporation - Princeton NJ

International Classification:

G01N 2726
G01N 2100
B01L 1100

US Classification:

204601

Abstract:

The present invention provides a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions. The distribution system can comprise an alpha reservoir and a beta reservoir, a first set of parallel and adjacent first and second feeder channels and a second set of parallel and adjacent third and fourth feeder channels which are offset from the first and second feeder channels, wherein (a) the first and third feeder channels are connected to the alpha reservoir via a first connector channel that is situated above or below the second and fourth feeder channels and are independent of the beta reservoir and (b) the second and fourth feeder channels are connected to the beta reservoir via a second connector channel that is situated above or below the first and third feeder channels and are independent of the alpha reservoir. The distribution system is preferably a microscale distribution system. Various particular mechanisms for controlling flow into a liquid distribution system are described.

US Patent:

62598465, Jul 10, 2001

Filed:

Oct 15, 1999

Appl. No.:

9/419374

Inventors:

William Ronald Roach - Rocky Hill NJ
Bawa Singh - Voorhees NJ
William Chiang - Monmouth Junction NJ
Zilan Shen - Wait Windsor NJ
Vipulkumar K. Patel - South Brunswick NJ

Assignee:

Sarnoff Corporation - Princeton NJ

International Classification:

G02B 602
G02B 616

US Classification:

385123

Abstract:

A display as for images and/or information comprises a plurality of light-emitting fibers disposed in side-by-side arrangement to define a viewing surface. Each light-emitting fiber includes a plurality of light-emitting elements disposed along its length, each having two electrodes between which are applied electrical signals to cause the light-emitting element to emit light to display a pixel or sub-pixel of the image and/or information. The light-emitting fiber includes an electrical conductor disposed along its length to serve as a first electrode, a layer of light-emissive material disposed thereon, and a plurality of electrical contacts disposed on the light-emissive material to serve as the second electrodes of the light-emitting elements. Preferably, the conductors, light-emissive layer and plurality of electrical contacts are formed in a continuous process wherein a transparent fiber passes through a plurality of processing chambers for receiving the electrical conductor, the light-emissive layer and the plurality of electrical contacts thereon.

US Patent:

20200255552, Aug 13, 2020

Filed:

Apr 27, 2020

Appl. No.:

16/859001

Inventors:

- Basel, CH
William Chiang - Pennington NJ, US
Frank Kerrigan - Wadebridge, GB
Stuart Green - Camelford, GB
Craig Robson - Camelford, GB
Howard Easterfield - Bude, GB

International Classification:

C08F 8/34
G01N 27/327
C07D 417/14
C08G 73/02
C07D 279/20
A61K 49/00
C08G 75/24
C12Q 1/00
C08G 59/40
C08F 8/30
C07D 279/08

Abstract:

A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

US Patent:

20180194877, Jul 12, 2018

Filed:

Mar 8, 2018

Appl. No.:

15/915184

Inventors:

- Basel, CH
William Chiang - Pennington NJ, US
Frank Kerrigan - Wadebridge, GB
Stuart Green - Camelford, GB
Craig Robson - Camelford, GB
Howard Easterfield - Bude, GB

International Classification:

C08F 8/34
G01N 27/327
C07D 417/14
C08G 73/02
C07D 279/20
A61K 49/00
C07D 279/08
C12Q 1/00
C08G 59/40
C08F 8/30
C08G 75/24

Abstract:

A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

US Patent:

20170044276, Feb 16, 2017

Filed:

Oct 26, 2016

Appl. No.:

15/334814

Inventors:

- Basel, CH
William Chiang - Pennington NJ, US
Frank Kerrigan - Wadebridge, GB
Stuart Green - Camelford, GB
Craig Robson - Camelford, GB
Howard Easterfield - Bude, GB

International Classification:

C08F 8/34
G01N 27/327
C07D 417/14

Abstract:

A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.