William Robert Mcdaniel

US Patent:

8067470, Nov 29, 2011

Filed:

Feb 1, 2008

Appl. No.:

12/012198

Inventors:

William Robert McDaniel - Franklin TN, US

International Classification:

A61K 31/201

US Classification:

514560

Abstract:

A preparation for the topical application of linoleic acid to treat male and female androgenetic alopecia, age-related alopecia, and keratosis pilaris contains between about 0. 1% and about 10%, preferably between about 1% and about 5%, and specifically about 2% linoleic acid by volume in its carrier vehicle. This acts to correct the local linoleic acid deficiency that exists in the follicles in these conditions and provides linoleic acid to suppress growth of with resultant reduction in its porphyrin production which in turn reduces microinflammation and altered keratinization that damages follicles and eliminates functioning follicles in alopecia and causes follicle plugging in keratosis pilaris.

US Patent:

56623046, Sep 2, 1997

Filed:

Jun 26, 1995

Appl. No.:

8/494766

Inventors:

William R. McDaniel - Brentwood TN

International Classification:

B65D 6300

US Classification:

248499

Abstract:

A hollow, molded, cylindrical screw-threaded device for removably anchoring objects such as beach umbrellas, ropes, pet leashes, and the like into sand comprises a hollow cylinder with two fixed molded perpendicular winglike projections for its insertion. A thumbscrew in the side of the cylinder allows for grasping and release of objects inserted into the anchoring device. Screw threads which taper in diameter and depth successively as the tip is approached allow for easier insertion into compact deeper sand and also for firmer anchoring in looser surface sand. Beveled lower thread surfaces allow for easier insertion of the device and flat upper thread surfaces afford greater resistance against forcible removal of the device from the sand. Moveable loops of two alternate designs allow for pivoting attachment points for ropes, pet leashes, and the like.

US Patent:

54438446, Aug 22, 1995

Filed:

Jan 27, 1994

Appl. No.:

8/187138

Inventors:

William R. McDaniel - Brentwood TN

International Classification:

A61K 748
A61K 700

US Classification:

424484

Abstract:

A preparation for topical application of linoleic acid, for treatment of acne, and Propionibacteriem acnes, contains between about 0. 1% and about 10%, preferably between about 1% and about 5% and specifically about 2% of linoleic acid. This acts both as an antibiotic and as a means for correcting the essential fatty acid imbalance in sebum which causes follicular plugging and triggers the process.

US Patent:

52097188, May 11, 1993

Filed:

Oct 28, 1991

Appl. No.:

7/783230

Inventors:

William R. McDaniel - Brentwood TN

International Classification:

A61F 1300
A61F 1500
A61F 528
A61F 530

US Classification:

602 53

Abstract:

A disposable pressure applying bandage for superficial wounds comprises a pad, for placement on a wound, a flexible arcuate member having its convex surface against the pad, and adhesive material extending over the arcuate member, for attachement of the arcuate member and the pad over the wound. Attachment of the adhesive material to a patient's skin flattens the arcuate member, to a lesser or greater degree, applying pressure to the wound.

US Patent:

59523727, Sep 14, 1999

Filed:

Sep 17, 1998

Appl. No.:

9/156280

Inventors:

William Robert McDaniel - Brentwood TN

International Classification:

A61K 3135

US Classification:

514453

Abstract:

A method of treating rosacea in humans involving orally-administered or topically-applied ivermectin is disclosed. More specifically, oral ivermectin in a regimen of 200 micrograms per kilogram body weight per dose for 2 or 3 consecutive doses at least 3 and not more than 7 days apart as the preferred regimen or, alternatively, topical ivermectin compounded to a 2% concentration by weight in a cream, lotion, or gel carrier vehicle is administered as an effective treatment for all clinical stages and signs of rosacea in affected persons.

US Patent:

20180271761, Sep 27, 2018

Filed:

Mar 22, 2017

Appl. No.:

15/466821

Inventors:

William Robert McDaniel - Franklin TN, US

International Classification:

A61K 8/42
A61K 8/06
A61Q 5/02
A61K 8/04
A61K 8/02
A61Q 19/08
A61Q 19/00

Abstract:

A method of correcting the visible and microscopic signs of Dermatoheliosis (chronic ultraviolet light-damaged human skin) and its various clinical manifestations (wrinkling, sagging, fragility, melasma, Poikiloderma of Civatte, solar lentigines, and senile purpura) and also Androgenetic Alopecia and Seborrheic Keratoses consists of the administration of fatty acid derivatives capable of inhibiting mast cells and the mediators they release that cause local tissue damage. These fatty acid derivatives include palmitoylethanolamide (PEA) and related cannabinomimetic compounds and adelmidrol and related Autacoid Local Injury Antagonist amides (ALIAmides) which are administered orally or applied topically. Adelmidrol, the best absorbed topically, is applied in a concentration of between 1% and 10% by volume, with a preferred concentration of about 5% by volume. Normally produced in body tissues in response to the effects of painful and inflammatory mast cell mediators, these compounds must be added in these conditions to stop the progression of damage because the affected tissues lack inflammation due to the immunosuppressive effects of the chronic ultraviolet radiation that initiates and likely perpetuates them.

US Patent:

20150316483, Nov 5, 2015

Filed:

Dec 18, 2013

Appl. No.:

14/651500

Inventors:

- Stillwater OK, US
Peter G. Loges - Natick MA, US
William McDaniel - Shrewsbury MA, US
Kateri E. Paul - Medford MA, US
Lawrence F. Hancock - North Andover MA, US
Matthew Joseph Szabo - Stillwater OK, US

Assignee:

FLIR Detection, Inc. - Stillwater OK

International Classification:

G01N 21/78
G01N 31/22
G01N 21/76
B01L 3/00

Abstract:

Embodiments described herein related to devices and methods for the collection and/or determination of analytes, such as illicit substances including military explosives, explosives, and precursors thereof. In some cases, the device may be a disposable device that incorporates highly efficient sample collection in combination with microfluidic-based chemical analysis resulting in the rapid detection and identification of unknown materials. In some cases, multiple colorimetric detection chemistries may be employed, and the resulting “barcode” of color changes can be used to positively identify the presence and/or identity of the analyte.