William G Meathrel

US Patent:

7470397, Dec 30, 2008

Filed:

Oct 22, 2004

Appl. No.:

10/970383

Inventors:

William G. Meathrel - Glen Rock PA, US
Nathan A. Meyer - Glen Rock PA, US
Scott D. Barnhart - Glen Rock PA, US
Cathy M. Moritz - Glen Rock PA, US
Andrew P. Full - Glen Rock PA, US
Susan R. Newsom - Oceanside CA, US
Mary Robertson - Castletroy, IE

Assignee:

Adhesives Research, Inc. - Glen Rock PA

International Classification:

G01N 33/548
G01N 33/532

US Classification:

422 56, 424443, 424435, 435 681, 435 4, 436526, 436518

Abstract:

The invention provides disintegratable film compositions for diagnostic test devices. The films are prepared with a combination of components that yield films of sufficient film strength and desired disintegration profiles. A disintegratable film according to the present invention contains a water soluble high molecular weight component, a water soluble low molecular weight component, and one or more reagents for use in a diagnostic device. Optionally, the films further contain a starch component, a glucose component, a plasticizer and/or a humectant, and/or a filler. The invention further provides a diagnostic testing device, which includes a film according to an embodiment of the invention, and methods of using such devices.

US Patent:

7476533, Jan 13, 2009

Filed:

Apr 19, 2002

Appl. No.:

10/474920

Inventors:

William G Meathrel - York PA, US
Li-Hung Su - Loganville PA, US

Assignee:

Adhesives Research, Inc. - Glen Rock PA

International Classification:

G01N 33/53

US Classification:

4352872, 422 56, 422 57, 422 58, 422 61, 4352871, 435 4, 4352877, 4352879, 435810, 436514, 436518, 436169, 436810

Abstract:

Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary diagnostic devices include lateral flow devices, microfluidic devices and microtiter plates. The devices may also be comprised of low fluorescent material in order to facilitate any diagnostic determination by use of fluorescent emissions. Hydrophilic properties may be imparted to the cover plates or backing strips by physical or chemical treatment thereof. The cover plates or backing strips may exhibit heat sealable or pressure sensitive properties.

US Patent:

7727466, Jun 1, 2010

Filed:

Nov 21, 2008

Appl. No.:

12/275243

Inventors:

William G. Meathrel - Glen Rock PA, US
Nathan A. Meyer - Glen Rock PA, US
Scott D. Barnhart - Glen Rock PA, US
Cathy M. Moritz - Glen Rock PA, US
Andrew P. Full - Glen Rock PA, US
Susan R. Newsom - Oceanside CA, US
Mary Robertson - Castletroy, IE

Assignee:

Adhesives Research, Inc. - Glen Rock PA

International Classification:

G01N 33/548
G01N 33/532

US Classification:

422 56, 422 55, 422 50, 435 681, 435 4, 436526, 436518, 424443, 424435

Abstract:

The invention provides disintegratable film compositions for diagnostic test devices. The films are prepared with a combination of components that yield films of sufficient film strength and desired disintegration profiles. A disintegratable film according to the present invention contains a water soluble high molecular weight component, a water soluble low molecular weight component, and one or more reagents for use in a diagnostic device. Optionally, the films further contain a starch component, a glucose component, a plasticizer and/or a humectant, and/or a filler. The invention further provides a diagnostic testing device, which includes a film according to an embodiment of the invention, and methods of using such devices.

US Patent:

7927865, Apr 19, 2011

Filed:

Dec 5, 2008

Appl. No.:

12/328815

Inventors:

William Meathrel - York PA, US
Li-Hung Su - Loganville PA, US

Assignee:

Adhesives Research, Inc. - Glen Rock PA

International Classification:

G01N 33/53

US Classification:

4352872, 4352871, 435 4, 4352879, 435810, 422 56, 422 57, 422 58, 422 61, 436514, 436518, 436169, 436810

Abstract:

Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary diagnostic devices include lateral flow devices, microfluidic devices and microtiter plates. The devices may also be comprised of low fluorescent material in order to facilitate any diagnostic determination by use of fluorescent emissions. Hydrophilic properties may be imparted to the cover plates or backing strips by physical or chemical treatment thereof. The cover plates or backing strips may exhibit heat sealable or pressure sensitive properties.

US Patent:

20080124381, May 29, 2008

Filed:

Oct 11, 2007

Appl. No.:

11/907372

Inventors:

Scott D. Barnhart - York PA, US
Andrew P. Full - York PA, US
Cathy M. Moritz - Red Lion PA, US
William G. Meathrel - York PA, US
George Cramer - York PA, US
Mary Robertson - Castletroy, IE

International Classification:

A61F 13/00

US Classification:

424443

Abstract:

The invention provides integratable adhesive films containing a mixture of high molecular weight and low molecular weight water soluble components; and a pharmaceutically or cosmetically active ingredient. Optionally, the films contain a starch component, a polysaccharide component, a filler, a plasticizer and/or humectant. The films are preferably in the form of an adhesive layer having a thickness sufficient to disintegrate, when exposed to a moist environment and/or a trigger compound, and release the active ingredient. The films can be cut to any desired size or shape to provide conveniently useable unit dosage forms for administration to wet or moist body surfaces for human, pharmaceutical, cosmetic, or veterinary applications. The invention further provides various end uses and methods of administering the film compositions.

US Patent:

20100068820, Mar 18, 2010

Filed:

Jun 22, 2006

Appl. No.:

11/993039

Inventors:

William Meathrel - York PA, US
Benjamin Wagner - Red Lion PA, US

Assignee:

ADHESIVES RESEARCH, INC. - Glen Rock PA

International Classification:

G01N 33/48
C08F 6/00
C08G 63/91

US Classification:

436 95, 525 50, 525 542, 422 681

Abstract:

An adhesive is provided containing at least one synthetic polymer with receptor sites that enable the selective capture or release of a target molecule. A polymer is synthesized by polymerizing and cross-linking a functional monomer or functional copolymers in the presence of a target or template molecule allowing for reversible interactions between the polymer and the target molecule. The target molecule may be extracted from the polymer creating receptor sites complimentary to the target molecule. Alternatively, the target molecule may remain in the polymer network and be controllably released. The molecularly imprinted polymer is formulated into an adhesive. The adhesive can be used as a component in an in-vitro diagnostic device to release template molecules or to capture target molecules in vacated receptor sites in the synthetic polymer.

US Patent:

20110117174, May 19, 2011

Filed:

Jan 30, 2009

Appl. No.:

12/863893

Inventors:

Guillaume Kergosien - Chaville, FR
William Meathrel - York PA, US

Assignee:

L'Oreal S.A. - Paris

International Classification:

A61K 9/70

US Classification:

424443

Abstract:

The invention relates to adhesive articles containing at least one colorant and/or at least one active agent as well as to methods of using such articles on mucosis or keratin materials to achieve a desired result or benefit and to methods of making such adhesive articles.

US Patent:

20110165022, Jul 7, 2011

Filed:

Mar 15, 2011

Appl. No.:

13/048495

Inventors:

William G. MEATHREL - York PA, US
Li-Hung SU - Foster City CA, US

Assignee:

ADHESIVES RESEARCH, INC. - Glen Rock PA

International Classification:

G01N 33/00

US Classification:

422 681

Abstract:

Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary diagnostic devices include lateral flow devices, microfluidic devices and microtiter plates. The devices may also be comprised of low fluorescent material in order to facilitate any diagnostic determination by use of fluorescent emissions. Hydrophilic properties may be imparted to the cover plates or backing strips by physical or chemical treatment thereof. The cover plates or backing strips may exhibit heat sealable or pressure sensitive properties.