Xi Ming Chen

Address:

1427 Wheaton Ln, Silver Spring, MD 20902

VIN:

2T1BR32EX7C818957

Make:

TOYOTA

Model:

COROLLA

Year:

2007

US Patent:

7183300, Feb 27, 2007

Filed:

Nov 10, 2005

Appl. No.:

11/271437

Inventors:

Michael F. Summers - Ellicott City MD, US
Atul Agarwal - Hamden CT, US
Xi Chen - Killingworth CT, US
Milind Deshpande - Madison CT, US

International Classification:

A61K 31/4245
A61K 31/426
A61K 31/341
C07D 271/08
C07D 277/48
C07D 307/54

US Classification:

514364, 514377, 514461, 548125, 548196, 549473

Abstract:

Substituted aryl aminomethyl thiazole ureas and analogues thereof that act as inhibitors of viral capsid formation, including HIV capsid formation, are provided here. Generally the virus capsid formation inhibitors described herein are compounds of Formula I.

US Patent:

8445537, May 21, 2013

Filed:

Oct 9, 2009

Appl. No.:

12/576410

Inventors:

Alan E. Tomkinson - Glenwood MD, US
Xi Chen - Baltimore MD, US
Barbara Dziegielewska - Baltimore MD, US
Alexander D. Mackerell - Baltimore MD, US
Shijun Zhong - Ellicott City MD, US
Gerald M. Wilson - Middle River MD, US

Assignee:

STC.UNM - Albuquerque NM

International Classification:

A61K 31/16
A61K 31/13

US Classification:

514615, 514638

Abstract:

Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.

US Patent:

20100204120, Aug 12, 2010

Filed:

Feb 8, 2010

Appl. No.:

12/702209

Inventors:

Shibo Jiang - Fresh Meadows NY, US
Zhi Qi - Corona NY, US
Xi Chen - Elmhurst NY, US
Chungen Pan - Guangzho, CN

International Classification:

A61K 38/16
C07K 14/00
A61P 31/18

US Classification:

514 12, 530395

Abstract:

Disclosed herein are trimeric polypeptide pharmaceutical compositions comprising three monomers, each monomer comprising a polypeptide having the amino acid sequence of the N-terminal heptad repeat (NHR or HR1) or C-terminal heptad repeat (CHR or HR2) of the transmembrane glycoprotein of human immunodeficiency virus (HIV) and a trimerization motif.

US Patent:

20120319329, Dec 20, 2012

Filed:

Apr 20, 2012

Appl. No.:

13/452441

Inventors:

Xi Chen - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

B29C 53/02
B29C 59/02

US Classification:

264320, 425352

Abstract:

Self-assembled buckling patterns of thin films on compliant substrates can be used in micro-fabrication. However, most previous work has been limited to planar substrates, and buckling of films on curved substrates has not been widely explored. With the constraining effect from various types of substrate curvature, numerous new types of buckling morphologies can be derived. The morphologies not only enable true three-dimensional (3D) fabrication of microstructures and microdevices, but also can have important implications for the morphogenesis of quite a few natural and biological systems.

US Patent:

20220239382, Jul 28, 2022

Filed:

Jan 25, 2022

Appl. No.:

17/583317

Inventors:

- Espoo, FI
Xi CHEN - Aberdeen NJ, US

International Classification:

H04B 10/69
H04J 14/02
H04B 10/61

Abstract:

An apparatus includes an optical source of an optical wavelength carrier, an optical modulator to receive the optical wavelength carrier, and an optical data receiver. The optical data modulator is configured to produce, from the optical wavelength carrier, an optical signal to carry separate data on different first and second components thereof in individual modulation periods during data transmission and to carry a training sequence on one of the components during time slots for calibration. The first component is relatively phase offset from the second component in the optical signal. The optical data modulator alternates the one of the components between the first and second components over the time slots for calibration. The optical receiver is connected to receive a portion of the optical signal and to temporally interleave a measurement of a characteristic of the first component and a measurement of a characteristic of the second component over the time slots for calibration. The optical receiver is configured to feedback information to the optical data modulator based on the measured characteristics. The optical data modulator is configured to reduce an imbalance between the two components of the optical carrier during data transmission based on the information.

US Patent:

20230058338, Feb 23, 2023

Filed:

May 10, 2019

Appl. No.:

16/408659

Inventors:

- New York NY, US
Onur Cakmak - New York NY, US
Xi Chen - New York NY, US

Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY

International Classification:

F03G 7/06
C09J 5/00
C09J 11/00
C08K 11/00

Abstract:

Water-responsive actuators and methods for creating water responsive actuators are disclosed. In some embodiments, the disclosed subject matter includes a first layer, for example a plastic tape, and a second layer, for example bacterial spores and cured adhesive. The second layer can be created in a pattern. The pattern can include joints, which can contract when exposed to dry air and can thereby bend the actuator, and can expand when exposed to humid air and thereby return the actuator its original position.

US Patent:

20210005852, Jan 7, 2021

Filed:

Mar 11, 2019

Appl. No.:

16/979312

Inventors:

- New York NY, US
Guoyu QIAN - Wuhan, CN
Xi CHEN - New York NY, US
Xiangbiao LIAO - New York NY, US
Changmin SHI - College Park MD, US
Tianyang WANG - Columbus OH, US

Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY

International Classification:

H01M 2/02
H01M 4/587
H01M 4/38
H01M 4/66
H01M 2/16
H01M 2/20
H01M 10/052
H01M 10/058

Abstract:

An energy storage device is disclosed that includes an axial structure with two or more rigid energy storage units and conductive flexible components separating adjacent rigid energy storage units. The rigid energy storage units include a plurality of folded layers, including an anode layer, a cathode layer, a first current collector layer, a second current collector layer, one or more separator layers, and one or more tape layers. The adjacent rigid energy storage units are produced by folding the plurality of layers one or more times onto themselves at a plurality of locations along the axial structure. The axial structure is then sealed in an aluminized casing along with an electrolyte material. The energy storage device exhibits high energy density, high foldability, and excellent electrochemical performances by virtue of the folded rigid energy storage segments connected by the flexible components. The conductive flexible component functions in a similar way as the soft marrow between vertebrae in the spine, providing excellent overall flexibility.

US Patent:

20150306174, Oct 29, 2015

Filed:

Jul 10, 2015

Appl. No.:

14/796725

Inventors:

- New York NY, US
Zhi Qi - Corona NY, US
Xi Chen - Elmhurst NY, US
Chungen Pan - Guangdong Province, CN

International Classification:

A61K 38/16
C12N 7/00

Abstract:

Disclosed herein are trimeric polypeptide pharmaceutical compositions comprising three monomers, each monomer comprising a polypeptide having the amino acid sequence of the N-terminal heptad repeat (NHR or HR1) or C-terminal heptad repeat (CHR or HR2) of the transmembrane glycoprotein of human immunodeficiency virus (HIV) and a trimerization motif.