Xi I Chen

US Patent:

7183300, Feb 27, 2007

Filed:

Nov 10, 2005

Appl. No.:

11/271437

Inventors:

Michael F. Summers - Ellicott City MD, US
Atul Agarwal - Hamden CT, US
Xi Chen - Killingworth CT, US
Milind Deshpande - Madison CT, US

International Classification:

A61K 31/4245
A61K 31/426
A61K 31/341
C07D 271/08
C07D 277/48
C07D 307/54

US Classification:

514364, 514377, 514461, 548125, 548196, 549473

Abstract:

Substituted aryl aminomethyl thiazole ureas and analogues thereof that act as inhibitors of viral capsid formation, including HIV capsid formation, are provided here. Generally the virus capsid formation inhibitors described herein are compounds of Formula I.

US Patent:

8445537, May 21, 2013

Filed:

Oct 9, 2009

Appl. No.:

12/576410

Inventors:

Alan E. Tomkinson - Glenwood MD, US
Xi Chen - Baltimore MD, US
Barbara Dziegielewska - Baltimore MD, US
Alexander D. Mackerell - Baltimore MD, US
Shijun Zhong - Ellicott City MD, US
Gerald M. Wilson - Middle River MD, US

Assignee:

STC.UNM - Albuquerque NM

International Classification:

A61K 31/16
A61K 31/13

US Classification:

514615, 514638

Abstract:

Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.

US Patent:

20110198101, Aug 18, 2011

Filed:

Aug 19, 2009

Appl. No.:

12/998384

Inventors:

Aaron W. Sanders - Missouri City TX, US
Ed G. Rightor - Maidland MI, US
Keith p. Johnston - Austin TX, US
Stephanie Adkins - Austin TX, US
Quoc Nguyen - Austin TX, US
Xi Chen - Austin TX, US

International Classification:

E21B 43/16
C07C 43/04

US Classification:

166402, 568679

Abstract:

Embodiments of the present disclosure include compositions for use in enhanced oil recovery, and methods of using the compositions for recovering oil. Compositions of the present disclosure include a nonionic, non-emulsifying surfactant having a CO-philicity in a range of about 1.5 to about 5.0, carbon dioxide in a liquid phase or supercritical phase, and water, where the nonionic, non-emulsifying surfactant promotes a formation of a stable foam formed of carbon dioxide and water.

US Patent:

20120103635, May 3, 2012

Filed:

Aug 19, 2009

Appl. No.:

13/382166

Inventors:

Aaron W. Sanders - Missouri City TX, US
Keith P. Johnston - Austin TX, US
Quoc Nguyen - Austin TX, US
Stephanie Adkins - Austin TX, US
Xi Chen - Austin TX, US
Ed G. Rightor - Midland MI, US

International Classification:

E21B 43/16

US Classification:

166402

Abstract:

Embodiments of the present disclosure include dispersion compositions having a nonionic surfactant for use in enhanced petroleum recovery, and methods of using the dispersion compositions in petroleum recovery processes. For the various embodiments, the nonionic surfactant of the dispersion composition promotes the formation of a dispersion from carbon dioxide and water.

US Patent:

20210269318, Sep 2, 2021

Filed:

Jun 20, 2019

Appl. No.:

17/252360

Inventors:

- Houston TX, US
Fei TIAN - Houston TX, US
Gang CHEN - Carlisle MA, US
Bai SONG - Cambridge MA, US
Ke CHEN - Cambridge MA, US
Li SHI - Austin TX, US
Xi CHEN - Austin TX, US
Sean SULLIVAN - Austin TX, US
David BROIDO - Needham MA, US
Navaneetha Krishnan RAVICHANDRAN - Chestnut Hill MA, US

Assignee:

University of Houston System - Houston TX

International Classification:

C01B 35/04
C30B 29/40

Abstract:

A method for growing bulk boron arsenide (BA) crystals, the method comprising utilizing a seeded chemical vapor transport (CVT) growth mechanism to produce single BAs crystals which are used for further CVT growth, wherein a sparsity of nucleation centers is controlled during the further CVT growth. Also disclosed are bulk BAs crystals produced via the method.

US Patent:

20210024989, Jan 28, 2021

Filed:

Feb 20, 2019

Appl. No.:

16/971411

Inventors:

- Houston TX, US
Ping SONG - Houston TX, US
Xi CHEN - Houston TX, US

Assignee:

William Marsh Rice University - Houston TX

International Classification:

C12Q 1/6858

Abstract:

Provided herein are reagents and methods for simultaneously enriching many potential rare genetic variants at different genetic loci. The rare variants enriched can include single nucleotide polymorphisms (SNPs), single nucleotide variants, or small insertions and deletions. Embodiments of the invention include procedures for integration with downstream next generation sequencing (NGS) analysis. Embodiments of the invention include analysis of nonpathogenic SNPs for the determination of cell identity and detection of cell contamination using qPCR or NGS.

US Patent:

20210009872, Jan 14, 2021

Filed:

Jun 25, 2020

Appl. No.:

16/911943

Inventors:

- Evanston IL, US
Lingqiao Li - Houston TX, US
Xi Chen - Evanston IL, US

International Classification:

C09J 165/02
C08J 5/18

Abstract:

Curable compositions for dynamic epoxy-based thermoset adhesives and/or sealants are provided. Methods of applying the compositions to form strong, low-stress, cured adhesive polymer films are also provided. The cured polymer films use crosslinkers that include disulfide and carbon-nitrogen bonds, wherein the disulfide bonds impart dynamic chemistry to the polymer network structure in order to the achieve adaptable thermoset adhesives and sealants.

US Patent:

20200407482, Dec 31, 2020

Filed:

Jun 26, 2020

Appl. No.:

16/913635

Inventors:

- Evanston IL, US
Lingqiao Li - Houston TX, US
Xi Chen - Evanston IL, US

International Classification:

C08G 18/38
C08J 11/12
C08G 18/76
C08G 18/18
C08G 18/16

Abstract:

Polythiourethane polymer networks that can be processed and/or recycled are provided. Also provided are methods of forming the polythiourethane polymer networks using excess thiol and/or a dual catalyst system and methods for reprocessing and recycling the polyurethane polymer networks. The polythiourethane polymer networks are based on thiourethane dynamic chemistry.