Gerwin SCHALK - Glenmont NY, US Aiko K. THOMPSON - Garnerville NY, US Peter BRUNNER - Albany NY, US Xiang Yang CHEN - Albany NY, US Dennis J. McFARLAND - Albany NY, US
Assignee:
HEALTH RESEARCH, INC. - Menands NY
International Classification:
A61N 1/36
US Classification:
607 45, 607 59, 607 58, 607 48
Abstract:
The present invention provides methods, devices, and systems for restoring or improving nervous system function of a subject. Provided is a method involving: (i) providing an operant conditioning protocol effective to produce targeted neural plasticity (TNP) in a primary targeted central nervous system (CNS) pathway of a subject; and (ii) administering the operant conditioning protocol to the subject to elicit TNP in the primary targeted CNS pathway and to elicit generalized neural plasticity (GNP) in one or more other CNS pathway. The elicitation of the GNP in the one or more other CNS pathway serves to restore or improve a nervous system function of the subject. Provided is a device comprising a nerve stimulation-electromyographic recording component and a controller for operating the nerve stimulation-electromyographic recording component in accordance with an operant conditioning protocol.
System And Related Method To Restore And/Or Improve Nervous System Functions By Modifying Specific Nervous System Pathways
- Menands NY, US Gerwin SCHALK - Glenmont NY, US Aiko K. THOMPSON - Garnerville NY, US Peter BRUNNER - Albany NY, US Xiang Yang CHEN - Albany NY, US Dennis J. McFARLAND - Albany NY, US
Assignee:
Health Research, Inc. - Menands NY
International Classification:
A61N 1/36 A61N 1/04
Abstract:
The present invention provides methods, devices, and systems for restoring or improving nervous system function of a subject. Provided is a method involving: (i) providing an operant conditioning protocol effective to produce targeted neural plasticity (TNP) in a primary targeted central nervous system (CNS) pathway of a subject; and (ii) administering the operant conditioning protocol to the subject to elicit TNP in the primary targeted CNS pathway and to elicit generalized neural plasticity (GNP) in one or more other CNS pathway. The elicitation of the GNP in the one or more other CNS pathway serves to restore or improve a nervous system function of the subject. Provided is a device comprising a nerve stimulation-electromyographic recording component and a controller for operating the nerve stimulation-electromyographic recording component in accordance with an operant conditioning protocol.
Method And Device To Restore And/Or Improve Nervous System Functions By Modifying Specific Nervous System Pathways
- Menands NY, US Gerwin SCHALK - Glenmont NY, US Aiko K. THOMPSON - Garnerville NY, US Peter BRUNNER - Albany NY, US Xiang Yang CHEN - Albany NY, US Dennis J. McFARLAND - Albany NY, US
Assignee:
HEALTH RESEARCH, INC. - Menands NY
International Classification:
A61N 1/36 A61B 5/0492 A61N 1/04
US Classification:
600546, 607115, 607 59
Abstract:
The present invention provides methods, devices, and systems for restoring or improving nervous system function of a subject. Provided is a method involving: (i) providing an operant conditioning protocol effective to produce targeted neural plasticity (TNP) in a primary targeted central nervous system (CNS) pathway of a subject; and (ii) administering the operant conditioning protocol to the subject to elicit TNP in the primary targeted CNS pathway and to elicit generalized neural plasticity (GNP) in one or more other CNS pathway. The elicitation of the GNP in the one or more other CNS pathway serves to restore or improve a nervous system function of the subject. Provided is a device comprising a nerve stimulation-electromyographic recording component and a controller for operating the nerve stimulation-electromyographic recording component in accordance with an operant conditioning protocol.
Jude and Charles Lu of Washington University. The other authors are Matthew Parker, Armita Bahrami, Alberto Pappo, Sara Federico, James Dalton, Jianmin Wang, Xiang Chen, Jared Becksfort, Jianrong Wu, Catherine Billups, David Ellison and James Downing, all of St. Jude; Satish Tickoo, Adriana Heguy a