Xiaolin Li from Norcross, GA, age 55

Fu Xi He Mu Xi Di Shen Hua

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Author
Xiaolin Li

ISBN #
7533907396

Us Patents

Diarylamine-Containing Compounds And Compositions, And Their Use As Modulators Of C-Kit Receptors
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US Patent:

7563894, Jul 21, 2009
Filed:

Oct 31, 2007
Appl. No.:

11/932945
Inventors:

Valentina Molteni - San Diego CA, US
Shuli You - Shanghai, CN
Juliet Nabakka - Santee CA, US
Yi Liu - San Diego CA, US
Xiaolin Li - San Diego CA, US
Donatella Chianelli - San Diego CA, US
Jon Loren - San Diego CA, US
Xiaodong Liu - San Diego CA, US
Shifeng Pan - San Diego CA, US
Donald S. Karanewsky - Escondido CA, US
Pascal Furet - Thann, FR
Vito Guagnano - Basel, CH
Assignee:

IRM LLC - Hamilton
Novartis AG - Basel
International Classification:

C07D 403/10
C07D 403/14
C07D 239/42
A61K 31/505
US Classification:

544330, 514275
Abstract:

Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.

Diarylamine-Containing Compounds And Compositions, And Their Use As Modulators Of C-Kit Receptors
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US Patent:

7592349, Sep 22, 2009
Filed:

Oct 31, 2007
Appl. No.:

11/933056
Inventors:

Valentina Molteni - San Diego CA, US
Shuli You - Shanghai, CN
Juliet Nabakka - Santee CA, US
Yi Liu - San Diego CA, US
Xiaolin Li - San Diego CA, US
Donatella Chianelli - San Diego CA, US
Jon Loren - San Diego CA, US
Xiaodong Liu - San Diego CA, US
Shifeng Pan - San Diego CA, US
Donald S. Karanewsky - Escondido CA, US
Pascal Furet - Thann, FR
Vito Guagnano - Basel, CH
Assignee:

IRM LLC - Hamilton
Novartis AG - Basel
International Classification:

A61K 31/505
A61K 31/506
C07D 239/42
C07D 403/04
C07D 403/14
A61P 35/00
US Classification:

514275, 544330, 544331, 544332
Abstract:

Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.

Diarylamine-Containing Compounds And Compositions, And Their Use As Modulators Of C-Kit Receptors
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US Patent:

7638523, Dec 29, 2009
Filed:

Oct 31, 2007
Appl. No.:

11/933030
Inventors:

Valentina Molteni - San Diego CA, US
Shuli You - Shanghai, CN
Juliet Nabakka - Santee CA, US
Yi Liu - San Diego CA, US
Xiaolin Li - San Diego CA, US
Donatella Chianelli - San Diego CA, US
Jon Loren - San Diego CA, US
Xiaodong Liu - San Diego CA, US
Shifeng Pan - San Diego CA, US
Donald S. Karanewsky - Escondido CA, US
Pascal Furet - Thann, FR
Vito Guagnano - Basel, CH
Assignee:

IRM LLC - Hamilton
Novartis AG - Basel
International Classification:

A61K 31/505
A61K 31/506
A61P 19/02
A61P 37/08
A61P 9/02
A61P 17/06
A61P 1/04
A61P 1/16
A61P 25/20
C07D 239/42
C07D 403/10
C07D 403/14
US Classification:

514275, 544330
Abstract:

Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.

Compositions And Methods For Modulating C-Kit And Pdgfr Receptors
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US Patent:

7678792, Mar 16, 2010
Filed:

Oct 16, 2007
Appl. No.:

11/873196
Inventors:

Donatella Chianelli - San Diego CA, US
Christopher Cow - San Diego CA, US
Yun He - Shanghai, CN
Songchun Jiang - San Diego CA, US
Xiaolin Li - San Diego CA, US
Xiaodong Liu - San Diego CA, US
Zuosheng Liu - San Diego CA, US
Jon Loren - San Diego CA, US
Valentina Molteni - San Diego CA, US
Juliet Nabakka - Santee CA, US
Pingda Ren - San Diego CA, US
Taebo Sim - Seoul, KR
Xiaodong Wang - Chapel Hill NC, US
Shuli You - Shanghai, CN
Assignee:

IRM LLC - Hamilton
International Classification:

C07D 471/04
A61K 31/4375
A61K 31/497
A61K 31/501
A61K 31/5355
A61K 31/506
C07D 413/14
C07D 213/69
C07D 213/61
C07D 213/74
C07D 213/80
C07C 205/06
C07C 301/00
C07C 255/07
C07C 69/73
A61P 17/10
A61P 29/00
A61P 3/10
A61P 31/00
A61P 27/14
US Classification:

5142325, 514300, 51425304, 51425204, 5142345, 514275, 544362, 544238, 544127, 544331, 544 80, 544119, 546296, 546318, 546310, 546297, 546122, 568705, 558 44, 558410, 560 60
Abstract:

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit, PDGFRα, PDGFRβ, CSF1R, Abl, BCR-Abl, CSK, JNK1, JNK2, p38, p70S6K, TGFβ, SRC, EGFR, trkB, FGFR3, FLT3, Fes, Lck, Syk, RAF, MKK4, MKK6, SAPK2β, BRK, KDR, c-raf or b-raf kinase, or mutant forms thereof.

Compounds And Compositions As Lxr Modulators
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US Patent:

7846949, Dec 7, 2010
Filed:

Feb 11, 2005
Appl. No.:

10/589410
Inventors:

Valentina Molteni - San Diego CA, US
Xiaolin Li - Del Mar CA, US
Fang Liang - Carlsbad CA, US
Juliet Nabakka - Santee CA, US
Enrique Saez - San Diego CA, US
John Wityak - Carlsbad CA, US
Assignee:

IRM LLC - Hamilton
International Classification:

A61K 31/44
A61K 31/42
A61K 31/41
C07D 213/55
C07D 498/00
C07D 231/12
C07C 229/00
US Classification:

514357, 514378, 514406, 514359, 546335, 548242, 5483731, 560 41
Abstract:

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).

Compounds And Compositions As Lxr Modulators
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US Patent:

8158662, Apr 17, 2012
Filed:

Feb 11, 2005
Appl. No.:

10/589087
Inventors:

Valentina Molteni - San Diego CA, US
Xiaolin Li - Del Mar CA, US
Juliet Nabakka - Santee CA, US
David Archer Ellis - San Diego CA, US
Beth Anaclerio - San Diego CA, US
Enrique Saez - San Diego CA, US
John Wityak - Carlsbad CA, US
Assignee:

Hamilton
International Classification:

A61K 31/433
C07D 285/12
US Classification:

514363, 548136
Abstract:

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).

Pyrimidine Derivatives And Compositions As C-Kit And Pdgfr Kinase Inhibitors
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US Patent:

8268850, Sep 18, 2012
Filed:

May 1, 2008
Appl. No.:

12/598919
Inventors:

Xiaolin Li - San Diego CA, US
Xiaodong Liu - San Diego CA, US
Valentina Molteni - San Diego CA, US
Assignee:

IRM LLC - Hamilton
International Classification:

C07D 401/14
A61K 31/444
US Classification:

514275, 544331
Abstract:

The invention provides a novel class of pyrimidine derivatives, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases.

Heterocyclic Compounds And Compositions As C-Kit And Pdgfr Kinase Inhibitors
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US Patent:

8278452, Oct 2, 2012
Filed:

Feb 20, 2009
Appl. No.:

12/918801
Inventors:

Donatella Chianelli - San Diego CA, US
Xiaolin Li - San Diego CA, US
Xiaodong Liu - San Diego CA, US
Jon Loren - San Diego CA, US
Valentina Molteni - San Diego CA, US
Juliet Nabakka - San Diego CA, US
Vince Yeh - San Diego CA, US
Assignee:

IRM LLC - Hamilton
International Classification:

C07D 471/02
US Classification:

546122
Abstract:

The invention provides a novel class of compounds of Formula I: (I) pharmaceutical compositions comprising such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases.

Associate Director R And D

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Location:

8274 Torrey Gardens Pl, San Diego, CA 92129

Industry:

Biotechnology

Work:

Gimdx, Inc.
Associate Director R and D
Vascutech Diagnosis Dec 2012 - Nov 2014
Vice President Development
Hob Biotech Group Jan 2010 - Dec 2012
Cto, Director R and D
Orphagen Pharmaceuticals Aug 2004 - Jan 2010
Group Leader, Senior Scientist
X-Ceptor Therapeutics Jul 2002 - Aug 2004
Research Scientist I

Education:

Duke University 1993 - 1998
Doctorates, Doctor of Philosophy, Biochemistry Peking University 1988 - 1992
Bachelors, Bachelor of Science, Biology

Skills:

Biotechnology
Patents
Molecular Biology
Biochemistry
Lifesciences
Organic Chemistry
Drug Discovery
Protein Chemistry
Cell
Genomics
Assay Development
Drug Development
Life Sciences
Technology Transfer
Cro Management
Medical Devices
Biopharmaceuticals
Clinical Development

Interests:

Science and Technology
Social Services

Languages:

Mandarin
English

Xiaolin N Li

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Location:

8338 Entreken Way, San Diego, CA 92129

Industry:

Medical Practice

Languages:

English

Xiaolin Li

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Xiaolin Li

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Xiaolin Avril Li

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Graphic Design At Web2Asia

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Position:

Graphic Design at Web2Asia

Location:

Shanghai City, China

Industry:

Fine Art

Work:

Web2Asia - Shanghai since Apr 2013
Graphic Design
SO-IL - Brooklyn Oct 2010 - Feb 2013
Communications Manager
Green Kids Media Jan 2012 - Apr 2012
Graphic Design
Emmis Communications Sep 2011 - Dec 2011
Graphic Design Intern
EDC | Center for Children and Technology Jun 2011 - Aug 2011
Graphic Design Intern

Education:

New York Institute of Technology-Old Westbury 2009 - 2011
BFA, Communication Arts

Skills:

Adobe Creative Suite
Microsoft Office
Mac OS X
Final Cut Pro
OS X
InDesign
Graphic Design

Languages:

English
Chinese

Awards:

2012 Dean's Teach with Today’s Technology Challenge 1st Place
The Dean's Teach with Today’s Technology Challenge is a challenge to School of Management (SoM) students to help them incorporate the newest and greatest Web 2.0 technologies into the curriculum. Our proposal integrated Web2.0 applications such as Twitter, Slideshare, YouTube, Facebook into a web interface at Wix.com to deliver knowledge content for the MGMT201 course. Interactive management games were also integrated into the content pages. The course content is portable to both Android and iOS based smart phones and also to tablets such as the iPad.