Xing Ying Li

US Patent:

20110097753, Apr 28, 2011

Filed:

Oct 15, 2008

Appl. No.:

12/287916

Inventors:

Tianxin Wang - Boyds MD, US
Xing Xiang Li - Vienna VA, US

International Classification:

C12Q 1/66
C07H 17/00
C07H 15/26

US Classification:

435 8, 536 181, 536 174

Abstract:

The present invention relates to chemiluminescent method and regent to detect analyte. One aspect of the current invention relates to using enzyme substrate that can be cleaved by target enzyme to release chemiluminescent compound giving light signal for the detection of varieties of target enzymes. Another aspect of the current invention relates to use chemiluminescent enzyme coupled with analyte binding molecules to detect specific analyte molecules in a homogenous phase.

US Patent:

20110189655, Aug 4, 2011

Filed:

Feb 2, 2011

Appl. No.:

13/019737

Inventors:

Xing Xiang Li - Vienna VA, US
Tianxin Wang - Boyds MD, US

International Classification:

C12Q 1/70
C07H 15/26
C12Q 1/66

US Classification:

435 5, 536 174, 435 18, 435 8

Abstract:

The present invention relates to reagents and methods for influenza virus detection. These reagents and methods disclosed in the present invention enable simple, rapid, specific and sensitive detection of influenza virus types A and B. These reagents are N-acetylneuraminic acid-firefly luciferin conjugates which can be cleaved by influenza virus neuraminidase.