Tianxin Wang - Columbia MD, US Xing Li - Vienna VA, US
International Classification:
C12Q001/68 C07H021/04 C12M001/34
US Classification:
435006000, 536024300, 435287200
Abstract:
The methods and compositions provided herein are based on use of reporter system to detect multiple analyte in a sample. The reporter system can be a signal amplification system that includes a carrier, typically a particle containing an analyte binding moiety, and multiple copies of a signaling moiety. Different reporter system can bind with different analyte. Different reporter system or their signaling moiety can be distinguished and detected. In various embodiments, the signaling moiety is physically released from its carrier after the carrier has been bound to the analyte and distinguished and detected after the release.
Chemiluminescent Methods And Reagents For Analyte Detection
Tianxin Wang - Boyds MD, US Xing Xiang Li - Vienna VA, US
International Classification:
C12Q 1/66 C07H 17/00 C07H 15/26
US Classification:
435 8, 536 181, 536 174
Abstract:
The present invention relates to chemiluminescent method and regent to detect analyte. One aspect of the current invention relates to using enzyme substrate that can be cleaved by target enzyme to release chemiluminescent compound giving light signal for the detection of varieties of target enzymes. Another aspect of the current invention relates to use chemiluminescent enzyme coupled with analyte binding molecules to detect specific analyte molecules in a homogenous phase.
Reagents And Kits For Detection Of Influenza Virus And The Like
Xing Xiang Li - Vienna VA, US Tianxin Wang - Boyds MD, US
International Classification:
C12Q 1/70 C07H 15/26 C12Q 1/66
US Classification:
435 5, 536 174, 435 18, 435 8
Abstract:
The present invention relates to reagents and methods for influenza virus detection. These reagents and methods disclosed in the present invention enable simple, rapid, specific and sensitive detection of influenza virus types A and B. These reagents are N-acetylneuraminic acid-firefly luciferin conjugates which can be cleaved by influenza virus neuraminidase.