Xue Mei Zhou

US Patent:

7314750, Jan 1, 2008

Filed:

Nov 20, 2003

Appl. No.:

10/719956

Inventors:

Xue Mei Zhou - San Jose CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C12M 1/34
C12M 3/00
C07H 21/04
C12Q 1/68

US Classification:

4352872, 435 911, 435 6, 536 231, 536 243

Abstract:

The invention provides nucleic acid sequences which are complementary, in one embodiment, to a wide variety of Rat genes. The invention provides the sequences in such a way as to make them available for a variety of analyses. In one embodiment the nucleic acid sequences provided are present as an array of probes that may be used to measure gene expression of at least 20,000 rat genes. As such, the invention relates to diverse fields impacted by the nature of molecular interaction, including chemistry, biology, medicine, and medical diagnostics.

US Patent:

20030120432, Jun 26, 2003

Filed:

Nov 26, 2002

Appl. No.:

10/065868

Inventors:

Xue Mei Zhou - San Jose California, US
David Smith - Santa Clara California, US
Elizabeth Kerr - Redwood City California, US
Lianne McLean - Pacifica California, US
Shaw Sun - Fremont California, US
Michael Siani-Rose - San Francisco California, US
Michael Mittman - Palo Alto California, US
Shawn Becker - San Mateo California, US
Lee Jacobek - San Francisco California, US

Assignee:

Affymetrix, Inc. - Santa Clara 95051

International Classification:

C12Q001/68
G01N033/53
G06F019/00
G01N033/48
G01N033/50

US Classification:

702/020000, 435/006000, 435/007100

Abstract:

A genomic portal system is described that receives user-selected identifiers of potential probes. The system determines verified probes corresponding to the identifiers and generates a custom probe array design. The system then displays the custom probe array design to the user via a graphical user interface and receives a user selection specifying acceptance, modification, or rejection of the design. The system provides the user with the accepted or modified custom probe array. The system may also enable a number of users to share space on a custom probe array. Another optional feature is to enable a number of users to share in ordering portions of a lot of catalog probe arrays to take advantage of economies of scale from lot-size purchases.

US Patent:

20030198983, Oct 23, 2003

Filed:

Jan 31, 2003

Appl. No.:

10/355577

Inventors:

Xue Zhou - San Jose CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C12Q001/68
C12M001/34

US Classification:

435/006000, 435/287200

Abstract:

Nucleic acid sequences are disclosed which are complementary to a wide variety of Human genes. The sequences could be used for a variety of analyses. As such, methods of using the disclosed nucleic acid sequences are related to diverse fields impacted by the nature of molecular interaction, including chemistry, biology, medicine, and medical diagnostics.

US Patent:

20050026164, Feb 3, 2005

Filed:

Nov 20, 2003

Appl. No.:

10/719900

Inventors:

Xue Zhou - San Jose CA, US

Assignee:

Affymetrix, INC. - Santa Clara CA

International Classification:

C12Q001/68
C12M001/34

US Classification:

435006000, 435287200

Abstract:

The invention provides nucleic acid sequences which are complementary, in one embodiment, to a wide variety of mouse genes. The invention provides the sequences in such a way as to make them available for a variety of analyses. In one embodiment the nucleic acid sequences provided are present as an array of probes that may be used to measure gene expression of at least 30,000 mouse genes. As such, the invention relates to diverse fields impacted by the nature of molecular interaction, including chemistry, biology, medicine, and medical diagnostics.

US Patent:

20050032074, Feb 10, 2005

Filed:

Sep 9, 2003

Appl. No.:

10/658879

Inventors:

Nila Shah - Cupertino CA, US
Janet Warrington - Los Altos CA, US
Xue Zhou - San Jose CA, US
Michael Mittmann - Palo Alto CA, US
Rui Mei - Santa Clara CA, US

Assignee:

Affymetrix, INC. - Santa Clara CA

International Classification:

G06F017/60
C12Q001/68
G06F019/00
G01N033/48
G01N033/50

US Classification:

435006000, 702020000, 705003000

Abstract:

A method is described that receives user-selected sequence and provides a custom array designed for resequencing the user-selected sequence. The system determines probes corresponding to the sequence and to possible variants of the sequence and generates a custom probe array design. The system then displays the custom probe array design to the user via a graphical user interface and receives a user acceptance of the design. The system provides the user with the accepted custom probe array. The system may also enable a number of users to share space on a custom probe array. Another optional feature is to enable a number of users to share in ordering portions of a lot of catalog probe arrays to take advantage of economies of scale from lot-size purchases.