Yan Chen

US Patent:

8438853, May 14, 2013

Filed:

Oct 8, 2008

Appl. No.:

12/247615

Inventors:

Andrew Green - Jupiter FL, US
Peter Stuttaford - Jupiter FL, US
Yan Chen - Sammamish WA, US
Hany Rizkalla - Stuart FL, US

Assignee:

Alstom Technology Ltd. - Baden

International Classification:

F02C 1/00
F02G 3/00

US Classification:

60746, 60737, 60752, 60804

Abstract:

A combustor end cap assembly having an improved cooling configuration is disclosed. Embodiments of the present invention are directed towards an apparatus and method for cooling an effusion plate of the combustor end cap assembly. The combustor end cap assembly also incorporates an impingement plate having a plurality of cooling holes with the impingement plate positioned a predetermined distance from the effusion plate. The cooling fluid passes through the impingement plate and is directed towards and onto the effusion plate for cooling of the effusion plate.

US Patent:

20220318519, Oct 6, 2022

Filed:

May 11, 2022

Appl. No.:

17/741945

Inventors:

- Redmond WA, US
Ruihua Song - Beijing, CN
Min Zeng - Redmond WA, US
Yan Chen - Redmond WA, US
Yue Liu - Redmond WA, US

International Classification:

G06F 40/35
G06F 16/332
G06F 16/33

Abstract:

The present disclosure provides a technical solution related to establishing a characterized chatbot with personality. On one hand, a corpus database matched with a specific character may be established, and a generated regular/conventional response messages may be converted into a characterized response messages with character's features during conversation, so that the conversation style of a chatbot may be characterized with a certain character's features. On the other hand, a chatbot may select a response message with a specific emotion by using an emotion conversation table corresponding to a personality when generating the response message against a content of a conversation input by a user, so that a chatbot may be characterized and have certain personality.

US Patent:

20230025491, Jan 26, 2023

Filed:

Jul 21, 2022

Appl. No.:

17/870656

Inventors:

- Bothell WA, US
Yan Chen - Woodinville WA, US
Patrick D. Noble - Seattle WA, US
Vikas Patnaik - Mukilteo WA, US

International Classification:

F23C 7/06
F23C 6/04
F23N 1/00

Abstract:

Combustion systems and associated methods are disclosed herein. In some embodiments, a combustion system comprises a first combustion zone, a second combustion zone downstream of the first combustion zone, and a heat module thermally coupled to the first combustion zone and/or second combustion zone. The first combustion zone is configured to (i) receive and combust preheated air and a first fuel and (ii) generate a first exhaust gas, and the second combustion zone is configured to (i) receive and combust the first exhaust gas and a second fuel and (ii) generate a second exhaust gas. The first exhaust gas can have a first excess air and the second exhaust gas can have a second excess air less than the first excess air. The heat module can comprise a thermionic converter or another heat-to-electricity converter able to generate a power output.

US Patent:

20210324100, Oct 21, 2021

Filed:

Jun 21, 2021

Appl. No.:

17/353648

Inventors:

- Seattle WA, US
- New York NY, US
Rupesh AMIN - Seattle WA, US
Aye CHEN - Seattle WA, US
Kimberly HARRINGTON - Seattle WA, US
Collin HAUSKINS - Seattle WA, US
Erik HESS - Seattle WA, US
Cyr DE IMUS - Seattle WA, US
Jon JONES - Seattle WA, US
Audrey OLSHEFSKY - Seattle WA, US
Stefan PONKO - Seattle WA, US
Ruth SALMON - Seattle WA, US
Semih TAREEN - Seattle WA, US
Rebecca WU - Seattle WA, US
Yan CHEN - Seattle WA, US
Steven M. SHAMAH - Seattle WA, US
Csaba PAZMANY - Seattle WA, US
Jui DUTTA-SIMMONS - Seattle WA, US
Mariana Cota STIRNER - Seattle WA, US
Melissa WORKS - Seattle WA, US

Assignee:

Juno Therapeutics, Inc. - Seattle WA
Memorial Sloan Kettering Cancer Center - New York NY

International Classification:

C07K 16/28
A61K 35/17
C07K 14/725
A61P 35/00
A61K 39/395
C07K 14/705
C12Q 1/6848

Abstract:

Provided herein are chimeric receptors, such as chimeric antigen receptors (CARs), comprising BCMA-binding molecules, such as anti-BCMA antibodies and antigen-binding fragments thereof, such as heavy chain variable (V) regions and single-chain antibody fragments, and encoding polynucleotides. In some embodiments, the anti-BCMA chimeric receptors specifically bind to BCMA. Among the anti-BCMA-binding molecules are human antibodies, including those that compete for binding to BCMA with reference antibodies, such as a non-human reference antibody. Also provided are genetically engineered cells expressing the CARs and uses thereof such as in adoptive cell therapy.

US Patent:

20200392236, Dec 17, 2020

Filed:

Nov 1, 2018

Appl. No.:

16/760411

Inventors:

- Seattle WA, US
Steven M. SHAMAH - Seattle WA, US
Yan CHEN - Seattle WA, US
Rebecca WU - Seattle WA, US
Collin HAUSKINS - Seattle WA, US
Csaba PAZMANY - Seattle WA, US
Jui DUTTA-SIMMONS - Seattle WA, US
Kimberly HARRINGTON - Seattle WA, US

Assignee:

Juno Therapeutics, Inc. - Seattle WA

International Classification:

C07K 16/28
C07K 14/705
C07K 14/535
C12N 15/867
A61P 35/00

Abstract:

Provided herein are BCMA-binding molecules, including anti-BCMA antibodies and antigen-binding fragments thereof such as heavy chain variable (VH) regions and single-chain antibody fragments, and chimeric receptors comprising the anti-BCMA binding molecules such as chimeric antigen receptors (CARs). In some embodiments, the anti-BCMA antibodies or antigen-binding fragments thereof specifically bind to BCMA-1. Among the anti-BCMA antibodies are human antibodies, including those that compete for binding to BCMA with reference antibodies, such as a non-human reference antibody. Also provided are genetically engineered cells expressing the CARs or BCMA-binding molecules and uses thereof such as in adoptive cell therapy.

US Patent:

20200342179, Oct 29, 2020

Filed:

Dec 13, 2018

Appl. No.:

16/765368

Inventors:

- Redmond WA, US
Ruihua Song - Beijing, CN
Min Zeng - Redmond WA, US
Yan Chen - Redmond WA, US
Yue Liu - Redmond WA, US

International Classification:

G06F 40/35
G06F 16/332
G06F 16/33

Abstract:

The present disclosure provides a technical solution related to establishing a characterized chatbot with personality. On one hand, a corpus database matched with a specific character may be established, and a generated regular/conventional response messages may be converted into a characterized response messages with character's features during conversation, so that the conversation style of a chatbot may be characterized with a certain character's features. On the other hand, a chatbot may select a response message with a specific emotion by using an emotion conversation table corresponding to a personality when generating the response message against a content of a conversation input by a user, so that a chatbot may be characterized and have certain personality.

Address:

702 W Casino Rd APT 30, Everett, WA 98204

VIN:

1HGCM56847A066763

Make:

HONDA

Model:

ACCORD

Year:

2007