Yasheen Te Zhou from 62 Sanders Ranch Rd, Moraga, CA 94556, age 58, Phone: 9253775243

Resumes

Head Of Computational Chemistry Group, Senior Research Fellow

view source

Location:

62 Sanders Ranch Rd, Moraga, CA 94556

Industry:

Biotechnology

Work:

Chiron Novartis 2001 - 2007
Computational Chemist
Anacor Pharmaceuticals 2001 - 2007
Head of Computational Chemistry Group, Senior Research Fellow
Novartis 2005 - 2007
Scientist
Chiron Corporation 2001 - 2005
Scientist
Sioc 1989 - 1992
Research Associate

Education:

University of Illinois at Chicago 1993 - 1999

Skills:

Drug Discovery
Drug Design

Languages:

English

Us Patents

Indolocarbazole Anticancer Agents And Methods Of Using Same
view source
US Patent:

7122526, Oct 17, 2006
Filed:

Jun 30, 2003
Appl. No.:

10/610290
Inventors:

Ze-Qi Xu - Woodridge IL, US
Yasheen Zhou - Moraga CA, US
Michael T. Flavin - Darien IL, US
Assignee:

Nanosphere, Inc. - Northbrook IL
International Classification:

A01N 43/04
A61K 31/70
C07G 3/00
C07G 11/00
C07H 15/00
C07H 17/00
US Classification:

514 43, 514 25, 536 174, 536 177, 536 187
Abstract:

The present invention relates to anti-tumor compounds, compositions and methods. In particular, the invention relates to indolocarbazole analogues of the following general formulas that inhibit topoisomerase I activity.

Substituted 2,5-Heterocyclic Derivatives
view source
US Patent:

7470701, Dec 30, 2008
Filed:

Mar 30, 2005
Appl. No.:

11/095993
Inventors:

Xiaodong Lin - Walnut Creek CA, US
Alice Rico - Berkeley CA, US
Xiaojing Michael Wang - Livermore CA, US
Yasheen Zhou - Moraga CA, US
Ann B. Jefferson - Oakland CA, US
Annette Walter - Mill Valley CA, US
Assignee:

Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
International Classification:

A61K 31/506
C07D 401/04
C07D 239/42
US Classification:

514275, 544331
Abstract:

The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula:.

2-Amino-7,8-Dihydro-6H-Pyrido[4,3-D]Pyrimidin-5-Ones
view source
US Patent:

7671059, Mar 2, 2010
Filed:

Sep 28, 2006
Appl. No.:

11/541462
Inventors:

Timothy D. Machajewski - Emeryville CA, US
Cynthia M. Shafer - Emeryville CA, US
Christopher McBride - Emeryville CA, US
Brandon M. Doughan - Emeryville CA, US
Barry H. Levine - Emeryville CA, US
Yi Xia - Emeryville CA, US
Maureen McKenna - Emeryville CA, US
Kris Mendenhall - Emeryville CA, US
Yasheen Zhou - Emeryville CA, US
Kristin Brinner - Emeryville CA, US
Zhenhai Gao - Emeryville CA, US
Daniel Poon - Emeryville CA, US
Paul Barsanti - Emeryville CA, US
Xiaodong Lin - Emeryville CA, US
Abran Costales - Emeryville CA, US
Alice Rico - Emeryville CA, US
Nathan Brammeier - Emeryville CA, US
Teresa Pick - Emeryville CA, US
Paul A. Renhowe - Emeryville CA, US
Assignee:

Novartis AG - Basel
International Classification:

A61K 31/519
A61K 31/5355
C07D 471/04
C07D 487/04
C07D 413/06
A61P 35/00
US Classification:

51425505, 544279, 544117, 5142342, 546220, 546209, 560 42, 548204
Abstract:

Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.

Quinazolines For Pdk1 Inhibition
view source
US Patent:

7932262, Apr 26, 2011
Filed:

Apr 5, 2007
Appl. No.:

12/295967
Inventors:

Savithri Ramurthy - Walnut Creek CA, US
Xiaodong Lin - Walnut Creek CA, US
Sharadha Subramanian - San Ramon CA, US
Alice Rico - Castro Valley CA, US
Rama Jain - Fremont CA, US
Jeremy M. Murray - Emeryville CA, US
Stephen E. Basham - Oakland CA, US
Robert L. Warne - San Leandro CA, US
Wei Shu - Danville CA, US
Yasheen Zhou - Moraga CA, US
Jeffrey Dove - Castro Valley CA, US
Mina Aikawa - Alameda CA, US
Payman Amiri - Walnut Creek CA, US
Weibo Wang - Moraga CA, US
Johanna M. Jansen - San Francisco CA, US
Allan S. Wagman - Belmont CA, US
Keith B. Pfister - San Ramon CA, US
Simon Ng - Walnut Creek CA, US
Assignee:

Novartis AG - Basel
International Classification:

A61K 31/517
US Classification:

5142664, 544292
Abstract:

The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

Trisubstituted Boron-Containing Molecules
view source
US Patent:

8343944, Jan 1, 2013
Filed:

Jul 27, 2010
Appl. No.:

12/844748
Inventors:

Yi Xia - Palo Alto CA, US
Michael Richard Kevin Alley - Santa Clara CA, US
Yasheen Zhou - Moraga CA, US
Rajeshwar Singh - Edmonton, CA
Charles Ding - San Mateo CA, US
Kathy Cao - Sunnyvale CA, US
Jacob J. Plattner - Orinda CA, US
Ligong Ou - Edmonton, CA
Guofeng Jia - Edmonton, CA
Neerja Saraswat - Edmonton CA, US
Sreekanth Ramachandran - Edmonton, CA
Ding Zhou - Shanghai, CN
Assignee:

Anacor Pharmaceuticals, Inc. - Palo Alto CA
International Classification:

A61K 31/69
C07F 5/04
US Classification:

514 64, 558288
Abstract:

This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.

Boron-Containing Small Molecules
view source
US Patent:

8461134, Jun 11, 2013
Filed:

Nov 11, 2010
Appl. No.:

12/944690
Inventors:

Vincent S. Hernandez - Watsonville CA, US
Xianfeng Li - Cupertino CA, US
Suoming Zhang - Palo Alto CA, US
Tsutomu Akama - Sunnyvale CA, US
Yanchen Zhang - Union City CA, US
Yang Liu - Foster City CA, US
Jacob J. Plattner - Orinda CA, US
Michael Richard Kevin Alley - Santa Clara CA, US
Yasheen Zhou - Moraga CA, US
James A. Nieman - Sherwood Park CA, US
Assignee:

Anacor Pharmaceuticals, Inc. - Palo Alto CA
International Classification:

A61K 31/18
A61K 31/69
C07F 5/02
A61P 31/04
US Classification:

514 64, 564 8, 564 86, 564 92
Abstract:

This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.

Boron-Containing Small Molecules
view source
US Patent:

8461336, Jun 11, 2013
Filed:

Sep 2, 2009
Appl. No.:

13/062491
Inventors:

Yasheen Zhou - Moraga CA, US
Yong Kang Zhang - San Jose CA, US
Tsutomu Akama - Sunnyvale CA, US
Kurt Jarnagin - San Mateo CA, US
Assignee:

Anacor Pharmaceuticals, Inc. - Palo Alto CA
International Classification:

C07F 5/02
A61K 31/69
US Classification:

546 13, 514 64
Abstract:

This invention provides, among other things, novel compounds useful for treating inflammatory conditions, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Boron-Containing Small Molecules For Controlling Ectoparasites
view source
US Patent:

8546357, Oct 1, 2013
Filed:

Nov 16, 2012
Appl. No.:

13/678578
Inventors:

Jean Marie Defauw - New Palastine IN, US
Jacob J. Plattner - Orinda CA, US
William Hunter White - Greenfield IN, US
Joseph Raymond Winkle - Carmel IN, US
Yong-Kang Zhang - San Jose CA, US
Yasheen Zhou - Moraga CA, US
Assignee:

Eli Lilly and Company - Indianpolis IN
Anacor Pharmaceuticals, Inc. - Palo Alto CA
International Classification:

A61K 31/69
A61K 31/42
C07D 231/00
C07D 207/40
C07F 5/04
US Classification:

514 64, 514378, 548110, 548240, 558288
Abstract:

This invention provides novel compounds, methods of using the compounds, and pharmaceutical compositions containing the compounds.

Yasheen Te Zhou

Yasheen Zhou Phones & Addresses

Work

Education

Skills

Languages

Industries

Resumes

Head Of Computational Chemistry Group, Senior Research Fellow

Us Patents

Indolocarbazole Anticancer Agents And Methods Of Using Same

Substituted 2,5-Heterocyclic Derivatives

2-Amino-7,8-Dihydro-6H-Pyrido[4,3-D]Pyrimidin-5-Ones

Quinazolines For Pdk1 Inhibition

Trisubstituted Boron-Containing Molecules

Boron-Containing Small Molecules

Boron-Containing Small Molecules

Boron-Containing Small Molecules For Controlling Ectoparasites