Yi Zhang

US Patent:

6506738, Jan 14, 2003

Filed:

Sep 14, 2001

Appl. No.:

09/952736

Inventors:

Kuo-Long Yu - Zionsville IN
Rita Civiello - Killingworth CT
Keith Combrink - Wallingford CT
Hatice Belgin Gulgeze - Middletown CT
Bradley C. Pearce - East Hampton CT
Xiangdong Wang - Guilford CT
Nicholas A. Meanwell - East Hampton CT
Yi Zhang - Evansville IN

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D40114

US Classification:

514 80, 51425406, 514269, 514322, 514363, 514364, 514370, 514381, 514387, 544139, 544310, 544370, 546199, 5462737, 548113, 548139, 548132, 548181, 548250, 5483507

Abstract:

The present invention concerns antiviral compounds, their compositions, and use in the treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection.

US Patent:

6774134, Aug 10, 2004

Filed:

Nov 16, 2001

Appl. No.:

09/994012

Inventors:

Kuo-Long Yu - Zionsville IN
Rita L. Civiello - Killingworth CT
Keith D. Combrink - Wallingford CT
Hatice Belgin Gulgeze - Middletown CT
Ny Sin - Meriden CT
Xiangdong Wang - Guilford CT
Nicholas Meanwell - East Hampton CT
Brian Lee Venables - Milford CT
Yi Zhang - Evansville IN
Bradley C. Pearce - East Hampton CT
Zhiwei Yin - Meriden CT
Jan Willem Thuring - Hamden CT

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

A61K 314709

US Classification:

514312, 546153, 546155, 546157

Abstract:

The present invention concerns antiviral compounds, their methods of preparation and their compositions, and use in the treatment of viral infections. More particularly, the invention provides heterocyclic substituted 2-methylbenzimidazole derivatives for the treatment of respiratory syncytial virus infection.

US Patent:

6844342, Jan 18, 2005

Filed:

Aug 19, 2003

Appl. No.:

10/643411

Inventors:

Kuo-Long Yu - Zionsville IN, US
Rita L. Civiello - Killingworth CT, US
Keith D. Combrink - Wallingford CT, US
Hatice Belgin Gulgeze - Middletown CT, US
Ny Sin - Meriden CT, US
Xiangdong Wang - Guilford CT, US
Nicholas Meanwell - East Hampton CT, US
Brian Lee Venables - Milford CT, US
Yi Zhang - Evansville IN, US
Bradley C. Pearc - East Hampton CT, US
Zhiwei Yin - Meriden CT, US
Jan Willem Thuring - Hamden CT, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

A61K 3150
A61K 3144
A61K 3166
A61K 31415
C07D49802

US Classification:

514248, 514300, 514105, 514394, 514361, 548221, 5483057, 548455, 546152, 546153, 546113, 544238, 544 582, 544105, 544279

Abstract:

The present invention concerns antiviral compounds, their methods of preparation and their compositions, and use in the treatment of viral infections. More particularly, the invention provides heterocyclic substituted 2-methylbenzimidazole derivatives for the treatment of respiratory syncytial virus infection.

US Patent:

6919331, Jul 19, 2005

Filed:

Dec 4, 2002

Appl. No.:

10/309505

Inventors:

Kuo-Long Yu - Zionsville IN, US
Xiangdong Wang - Guilford CT, US
Yaxiong Sun - Thousand Oaks CA, US
Christopher Cianci - Madison CT, US
Jan Willem Thuring - Antwerp, BE
Keith Combrink - Burleson TX, US
Nicholas Meanwell - East Hampton CT, US
Yi Zhang - San Diego CA, US
Rita L. Civiello - Killingworth CT, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D235/26
C07D401/06
C07D403/06
C07D413/14
C07D471/04

US Classification:

5142232, 51426623, 514303, 514312, 514364, 514387, 514397, 514400, 544 12, 544284, 546118, 546157, 548144, 5483051, 5483057, 5483101

Abstract:

The present invention concerns antiviral compounds, their methods of preparation and their compositions, and use in the treatment of viral infections. More particularly, the invention provides heterocyclic substituted 2-methylbenzimidazole derivatives for the treatment of respiratory syncytial virus infection.

US Patent:

7611619, Nov 3, 2009

Filed:

Jul 7, 2003

Appl. No.:

10/520554

Inventors:

Chad A. Mirkin - Wilmette IL, US
Yi Zhang - Evanston IL, US
Khalid Salaita - Evanston IL, US

Assignee:

Northwestern University - Evanston IL

International Classification:

C25F 3/00
C25F 1/00
C23C 22/82

US Classification:

205640, 205674, 205688, 205705

Abstract:

The invention provides a simple and convenient strategy for reducing the dimensions of organic micro- and nanostructures on metal surfaces. By varying electrochemical desorption conditions, organic structures patterned by Dip-Pen Nanolithography or any of the micro-contact printing procedures can be gradually desorbed in a controlled fashion. The electrochemical desorption is initiated at the exterior of the feature and moves inward as a function of time. The desorption process and adsorbate desorption are modified and controlled as a function of substrate morphology, adsorbate head and tail groups, and electrolyte solvent and salt. Different nanostructures made of different adsorbates can be miniaturized based upon judicious selection of adsorbate and supporting electrolyte.

US Patent:

20210248819, Aug 12, 2021

Filed:

Apr 2, 2021

Appl. No.:

17/221489

Inventors:

- Basking Ridge NJ, US
Yi Zhang - Chicago IL, US
Cong Nguyen - Chicago IL, US

International Classification:

G06T 17/20
G06K 9/00
H04L 29/06
G06K 9/46
G06K 9/20
G06K 9/62
H04N 13/271
H04N 13/254
G06T 15/20
G06T 19/20
G06T 19/00
H04N 7/14
H04N 7/15
G06T 7/73
H04N 13/214
G06F 3/0481
H04L 12/18
G06T 15/08

Abstract:

An exemplary method includes maintaining a receiver-side mesh-vertices list, receiving duplicative-vertex information from a sender, and responsively reducing the receiver-side mesh-vertices list in accordance with the received duplicative-vertex information, and rendering, using the reduced receiver-side mesh-vertices list, viewpoint-adaptive three-dimensional (3D) personas of a subject at least in part by weighting video pixel colors from different video-camera vantage points of video cameras that capture video streams of the subject, the weighting being performed according to a respective geometric relationship of each video-camera vantage point to a user-selected viewpoint.

US Patent:

20210074058, Mar 11, 2021

Filed:

Nov 4, 2020

Appl. No.:

17/089380

Inventors:

- Basking Ridge NJ, US
Yi Zhang - Chicago IL, US
Cong Nguyen - Chicago IL, US

International Classification:

G06T 17/20
G06F 3/0481
H04N 7/15
G06K 9/20
H04L 29/06
H04N 13/254
G06K 9/00
H04N 13/271
H04N 7/14
G06T 7/73
G06T 19/20
H04N 13/214
G06K 9/46
G06K 9/62
G06T 15/20
G06T 19/00

Abstract:

An exemplary method includes generating a 3D mesh of a subject based on frames of time-synchronized video streams of a subject, the frames associated with a first time and generating a transformed facial-mesh model based on a facial portion of the 3D mesh and a facial-mesh model. The method further includes generating a hybrid mesh by combining the transformed facial-mesh model and at least a portion of the 3D mesh. The method further includes generating a current 3D mesh based on frames of the time-synchronized video streams associated with a second time that temporally follows the first time. The method further includes generating a deformed historical 3D mesh by applying a non-rigid deformation process to the hybrid mesh based on the current 3D mesh. The method further includes compressing the deformed historical 3D mesh to form at least one triangle-based 3D submesh including a plurality of submesh triangles.

US Patent:

20210000395, Jan 7, 2021

Filed:

Sep 22, 2020

Appl. No.:

17/027887

Inventors:

- Evanston IL, US
- Urbana IL, US
Tyler R. RAY - Evanston IL, US
Johnathan T. REEDER - Plano TX, US
Yurina SEKINE - Evanston IL, US
Amay J. BANDODKAR - Evanston IL, US
Yi ZHANG - Evanston IL, US
Hexia GUO - Evanston IL, US
Sungbong KIM - Champaign IL, US
Diana OSTOJICH - Evanston IL, US

International Classification:

A61B 5/145
A61B 5/00
A61B 5/053
A61B 5/103
A61B 5/1455
B01L 3/00

Abstract:

A microfluidic system includes a flexible substrate having a skin-facing surface and a back-facing surface; a microfluidic network at least partially embedded in or supported by the flexible substrate; a sensor fluidically connected to the microfluidic network, wherein the microfluidic network is configured to transport a biofluid from a skin surface to the sensor; and a capping layer, having a capping layer skin-facing surface and a back-facing surface, wherein the back-facing surface of the capping layer is attached to the skin-facing surface of the substrate. The flexible substrate is at least partially formed of a thermoplastic elastomer or a polymer configured to provide a high barrier to vapor or liquid water transmission.