Yin Guan Lin

US Patent:

20150368317, Dec 24, 2015

Filed:

May 31, 2013

Appl. No.:

14/404939

Inventors:

- Cambridge MA, US
Xiaomei HE - Cambridge MA, US
Yan YIN - Cambridge MA, US
Yin Yin LIN - Cambridge MA, US
Brian COLLINS - Cambridge MA, US
Jennifer MURPHY - Cambridge MA, US
Ganesh KAUNDINYA - Cambridge MA, US

Assignee:

Momenta Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07K 14/705

Abstract:

The present disclosure provides, in part, methods for evaluating, identifying, and/or producing (e.g., manufacturing) a CTLA4-Fc fusion protein, e.g., abatacept. In some instances, methods herein allow highly resolved evaluation of abatacept useful for, inter alia, manufacturing abatacept, characterizing abatacept, identifying and/or confirming abatacept, monitoring the structure of abatacept, comparing abatacept preparations made over time or made under different conditions, and/or controlling the structure of abatacept.