Stephen J. Elledge - Houston TX, US Yolanda Sanchez - Cincinnati OH, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12N 9/12 C12N 9/10 A61K 38/00 C07K 1/00
US Classification:
435194, 435193, 530324, 530326, 530350
Abstract:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
Stephen Elledge - Houston TX, US Yolanda Sanchez - Cincinnati OH, US
International Classification:
C07K016/40
US Classification:
530/389100
Abstract:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
Stephen J. Elledge - Houston TX Yolanda Sanchez - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
A61K 3800
US Classification:
530324
Abstract:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
Stephen J. Elledge - Houston TX Yolanda Sanchez - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12Q 168 C12N 1563 C12N 120 C07H 2104
US Classification:
435 6
Abstract:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
Jan 2011 to 2000 Private Practice VeterinarianCalifornia Animal Hospital Los Angeles, CA May 2003 to Jun 2004 Veterinary TechnicianUCLA Department of Infectious Disease
2001 to 2003 Research Associate
Education:
University of California Davis, CA Jul 2010 Doctorate of Veterinary MedicineUniversity of California Davis, CA Jun 2004 Master of Science in Veterinary GeneticsUniversity of California Los Angeles, CA Jun 2001 Bachelor of Science in Biology