Young Ae Kang

US Patent:

6432974, Aug 13, 2002

Filed:

Jan 26, 2001

Appl. No.:

09/771316

Inventors:

Michael G. Kelly - Thousand Oaks CA
Young H. Kang - Robbinsville NJ

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 314745

US Classification:

514292, 546 84

Abstract:

Compounds of the formula are useful in the treatment of anxiety, depression and related disorders of the central nervous system and other conditions such as schizophrenia, sleep disorders, including instances of circadian rhythm, the treatment of alcohol and drug withdrawal and sexual dysfunction.

US Patent:

6689792, Feb 10, 2004

Filed:

Oct 12, 2001

Appl. No.:

09/976321

Inventors:

Michael G. Kelly - Newbury Park CA
Young H. Kang - Robbinsville NJ

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31454

US Classification:

514314, 514322, 514323, 514338, 514339, 546174, 546177, 546199, 546201, 5462734, 5462774, 5462777

Abstract:

Compounds of formula (1) are provided: wherein R and R are H, OH, F, Cl, Br, I, 1 to 6 carbon alkyl or alkenyl, 1 to 6 carbon alkoxy, aryl, OR , nitro, amino, CF or R and R are taken together to form a fused ring at the 2,3- or 3,4-positions providing a fused phenyl group or a benzodioxane group, or a 4- or 7-substituted indole group, or a 5- or 8-substituted quinoline group; R represents a group selected from hydrogen, a 1 to 6 carbon alkyl, a 1 to 4 carbon alkoxy or a halogen; R represents a group selected from hydrogen, 1 to 6 carbon alkyl or R ; R5 is CH Ph in which the phenyl ring can be optionally substituted by a group selected from OMe, halogen, CF ; X is selected from a group represented by C, CR , [[CHR ]] and CHCH ; A is selected from a group represented by N, NH, CH and CH ; B is selected from a group represented by O, S, H and H2; or A and B may be concatenated together to form indole, benzimidazole, indolone or indoline moieties; or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions and methods of treating central nervous system disorders utilizing these compounds.

US Patent:

7488517, Feb 10, 2009

Filed:

Mar 15, 2007

Appl. No.:

11/724418

Inventors:

Brian Whang - Fullerton CA, US
Young Choon Kang - Fullerton CA, US

International Classification:

B05D 5/00
B05D 1/18

US Classification:

427412, 4274301

Abstract:

A method of producing a porous, rubbery polymer coated sock comprising: 1) preparing a double layered sock; 2) wearing the sock on mold hanging on a continuous line; 3) pre-treating the sole portion of the sock a with calcium nitrate solution; 4) preparing a first nitrile rubber solution by stirring a solution comprising foaming agents and acrylo-nitrile butadiene rubber (NBR) at 1,200 r. p. m. for 30 minutes; 5) dipping the sock worn on the mold in a first, deep bath containing the first, foamed nitrile rubber solution; 6) air-drying the solvent in the polymer solution and developing foam in the rubber layer; 7) preparing a second, foamed nitrile rubber solution by stirring a solution comprising foaming agents and nitrile rubber at 1,200 r. p. m. for 30 minutes; 8) dipping sock worn on the mold in a second, shallow bath containing the second, foamed nitrile rubber solution; 9) air-drying the solvent in the second polymer solution and developing foam in the rubber layer; and 10) washing the sock from step 9) in a cleaning solution to eliminate the calcium nitrate and organic solvents and drying the washed sock 110 C. for 40 minutes.

US Patent:

63100665, Oct 30, 2001

Filed:

Feb 16, 2000

Appl. No.:

9/504703

Inventors:

Michael G. Kelly - Newbury Park CA
Young H. Kang - Robbinsville NJ

Assignee:

American Home Products Corp. - Madison NJ

International Classification:

A61K 31496
C07D40312
C07D40314
C07D40514

US Classification:

51425306

Abstract:

The present invention provides novel compounds of the general formula: ##STR1## wherein R. sub. 1 and R. sub. 2 are H, OH, F, Cl, Br, I, 1 to 6 carbon alkyl or alkenyl, 1 to 6 carbon alkoxy, aryl, OR. sub. 5, nitro, amino, CF. sub. 3 or R. sub. 1 and R. sub. 2 are taken together to form a fused ring at the 2,3- or 3,4-positions providing a fused phenyl group or a benzodioxane group, or a 4- or 7-substituted indole group, or a 4- or 5- or 8-substituted quinoline group; R. sub. 3 represents a group selected from hydrogen, a 1 to 6 carbon alkyl, a 1 to 4 carbon alkoxy or a halogen; R. sub. 4 represents a group selected from hydrogen, 1 to 6 carbon alkyl or R. sub. 5 ; R. sub. 5 is CH. sub. 2 Ph in which the phenyl ring can be optionally substituted by a group selected from OMe, halogen, CF. sub. 3 ; X is selected from a group represented by N, CR. sub. 4, CHR. sub.