Yu Z Chen

US Patent:

7410493, Aug 12, 2008

Filed:

May 15, 2000

Appl. No.:

09/570909

Inventors:

Yu Chen - Baltimore MD, US
Ming An Chen - Baltimore MD, US

International Classification:

A61B 17/00

US Classification:

606204

Abstract:

A method and device for the treatment of anxiety disorder, including panic attacks. A hammer is used to tap the cutaneous region of the bladder channel on the back until the skin turns pink. The skin on the abdomen, arms, legs, and buttocks can also be used for treatment. The hammer preferably has a magnetic piece in one end of the hammer head. The method can treat anxiety disorder including panic attack, general anxiety, phobia, posttraumatic stress disorder, stress related tension headache, insomnia, and any stress. Patients can use the hammer to treat themselves at home, office, and during traveling. The method and device are simple, effective, nontoxic, safe, have no side effects, inexpensive, and convenient.

US Patent:

20020169357, Nov 14, 2002

Filed:

May 11, 2001

Appl. No.:

09/853066

Inventors:

Yu Chen - Baltimore MD, US

International Classification:

A61N001/00

US Classification:

600/015000

Abstract:

A novel method and device to control appetite, reduce food craving, reduce excess food consumption and treat other eating disorders is provided by attaching or implanting one or more magnets on the acupoints or areas of the ears of human subjects or animals. The device of the invention includes magnets preferably of a circular configuration, having magnet strength of about 100-14,000 gauss. A magnet is attached on an auricular acupoint or area by adhesive plaster. The magnets, adhesive plasters, an illustration, and instruction will be packed in a kit.

US Patent:

58038965, Sep 8, 1998

Filed:

Aug 9, 1996

Appl. No.:

8/694746

Inventors:

Yu Chen - Baltimore MD

International Classification:

A61N 200

US Classification:

600 9

Abstract:

A method and novel hypoallergenic magnetic device for the treatment of diabetes mellitus is provided by the attachment, mounting or implanting to the ear of the subject along with the provision for supplementing the pancreatic hormones of the subject to assist in the maintenance and stabilization of the blood sugar in diabetic patients. The means for mounting or attaching the magnetic device of the invention includes attachment of the magnetic device by adhesives, adhesive plaster and, where the hypoallergenic materials of the magnet permit, implantation. The device of the invention includes novel hypoallergenic magnetic devices preferably of a circular configuration having a magnetic strength of about 100 to 14,000 gauss which is maintained at one or more locations in the ear 24 hours a day to assist in the lowering and stabilization of the blood sugar within a normal range between doses. The device of the invention may include in a kit one or more circular magnetic devices for external use having a strength from about 100 to 9,000 gauss together with a means for mounting the circular magnetic device in the auricle of the ear which may include a diagram and model of the ear illustrating various locations for attachment in the ear to assist in the placement of the circular magnetic device at one or more locations in the auricle of the ear.

US Patent:

60903899, Jul 18, 2000

Filed:

Oct 26, 1998

Appl. No.:

9/177973

Inventors:

Yu Chen - Baltimore MD

International Classification:

A61K 3578
A61K 920
A61K 948

US Classification:

4241951

Abstract:

A method and preparations for the treatment of vaginal yeast and other yeast infections is provided for the treatment of infections caused by Candida albicans and Cryptococcus neoformans. The method and preparations of the invention can also be used for other yeast and fungal infections including systemic, mucosal and cutaneous caused by Candida and Cryptococcus. The vaginal antiyeast and antifungal preparations include, in addition to suppositories and mouth washes, troches, lotions, creams, tablets and capsules containing gentian preparations as an active ingredient obtained from the plant Radix gentianae Longdancao. For systemic fungal infections gentian preparations from the plant Radix gentianae Longdancao are taken orally in the form of lozenges, tablets, capsules or in solution form for gargling or swallowing.

US Patent:

58372547, Nov 17, 1998

Filed:

Nov 14, 1996

Appl. No.:

8/748949

Inventors:

Yu Chen - Baltimore MD

International Classification:

A61K 3578
A61K 902
A61K 920
A61K 948

US Classification:

4241951

Abstract:

A method and preparations for the treatment of vaginal yeast and other yeast infections is provided for the treatment of infections caused by candida albicans and cryptococcus neoformans. The method and preparations of the invention can also be used for other yeast and fungal infections including systemic, mucosal and cutaneous caused by candida and cryptococcus. The vaginal antiyeast and antifungal preparations include, in addition to suppositories and mouth washes, troches, lotions, creams, tablets and capsules containing gentian preparations as an active ingredient obtained from the, plant Radix gentianae Longdancao other active ingredients which may also be present are American Radix Ginseng, Radix Scutellariae Basica Lensis and Fructus Gardeniae Jasminoidis. For systemic fungal infections gentian preparations from the plant Radix gentianae Longdancao are taken orally in the form of lozenges, tablets, capsules or in solution form for gargling or swallowing. The novel gentian preparations also can be applied topically for cutaneous yeast infections and are administered in the form of suppositories, lozenges and creams to treat mucosal yeast infections.

US Patent:

20210348119, Nov 11, 2021

Filed:

Oct 11, 2019

Appl. No.:

17/284215

Inventors:

- Rockville MD, US
Yu CHEN - Rockville MD, US
Anton SIMEONOV - Rockville MD, US

Assignee:

The United States of America as Represented By The Secretary of The Department of Health and Human - Rockville MD

International Classification:

C12N 5/00

Abstract:

Compositions and methods useful for culturing mammalian cells, tissues and/or organs are provided. The compositions contain Chroman 1 or its derivatives, may further include Emricasan or its derivatives, and may further include one or both of trans-ISRIB and polyamines. The compositions may be formulated as media additives, media concentrates or working media. The compositions and methods may be used to culture stem cells, progenitor cells, differentiated cells, isolated primary cells, secondary cells, immortalized cells, cell line cells, germline cells, somatic cells, or modified cells, including genetically modified cells. The compositions and methods may be used to culture, preserve or maintain cells, tissues, organs parts or organs, grow embryoid bodies, embryos, organs or organ parts.

US Patent:

20190167116, Jun 6, 2019

Filed:

Nov 15, 2018

Appl. No.:

16/192229

Inventors:

Yu Chen - College Park MD, US
Qinggong Tang - College Park MD, US
Udayakumar Kanniyappan - Hyattsville MD, US
Lin Z. Li - Aston PA, US
He Xu - Lansdowne PA, US
Yi Liu - College Park MD, US
Emily Conant - Philadelphia PA, US

International Classification:

A61B 5/00
A61B 1/07
A61B 1/04
A61B 1/06
A61B 1/00
A61B 10/02

Abstract:

In accordance with aspects of the present disclosure, an exemplary system includes a hollow probe having a lumen containing one or more excitation optical fiber(s) and one or more imaging optical fiber(s) where the probe is sized to access a person's body, a first light source optically coupled to the excitation fiber(s) and configured to emit light that excites fluorescence of NADH in breast tissue, a second light source optically coupled to the excitation fiber(s) and configured to emit light that excites fluorescence of FAD in tissue such as breast tissue, an image capturing device optically coupled to the imaging fiber(s), and a controller configured to control the first light source and the image capturing device to capture NADH fluorescence signals/intensities while the probe is within the person's body and control the second light source and the image capturing device to capture FAD fluorescence signals/intensities while the probe is within the person's body.

US Patent:

20160370285, Dec 22, 2016

Filed:

Jun 20, 2016

Appl. No.:

15/187727

Inventors:

- Bethesda MD, US
- College Park MD, US
Yu Chen - Rockville MD, US
Thomas Joshua Pfefer - Chevy Chase MD, US

International Classification:

G01N 21/27
A61B 5/00
G01N 33/49
C08L 83/04
C08J 3/00

Abstract:

Novel biophotonic phantoms are provided herein that can accurately mimic the optical properties of living tissue. The disclosed biophotonic phantoms comprise hemoglobin (Hb) in a native conformation that is distributed in a solid polymer matrix. Methods of producing the disclosed biophotonic phantoms are also provided. The biophotonic phantoms can be used, for example, to calibrate or test an optical imaging system, such as a near infrared spectroscopy imaging system.