Methods of reducing pre-existing humoral immunity to a viral immunogenic therapeutic agent such as adenovirus, using immunoapheresis are disclosed. Antibodies specific for the viral immunogenic therapeutic agent are selectively removed from the blood of an individual prior to administration of the viral immunogenic therapeutic agent by reaction extracorporeally with an immunosorbent which specifically binds the antibody. After the antibody is selectively removed from the blood, the blood is reinfused into the patient and the viral immunogenic therapeutic agent is administered. The invention also provides kits and compositions for selective removal of anti-viral antibody.
Apparatus And Method For Hermetically Sealing And Emi Shielding Integrated Circuits For High Speed Electronic Packages
An apparatus and method for hermetically sealing, EMI shielding integrated circuits for high-speed electronic devices using a combination of microstrip to buried stripline interface for signal transmission from the integrated circuit. The packaging provided comprises a first plurality of microstrips interconnecting the integrated circuit to a plurality of buried striplines exposed on a surface of the main substrate. A ceramic interposer placed over the main substrate âburiesâ a portion of the exposed striplines on the main substrate to thereby insulate these signal paths from a hermetically sealing, and EMI shielding metal lid placed over the integrated circuit. The metal lid and the seal ring brazed over the ceramic interposer thus provide both a hermetic seal and an electric radiation block. A reduction in dispersion due to the buried striplines is also achieved, as well as improving jitter performance.
High-Speed Package Design With Suspended Substrates And Pcb
An integrated high-speed package comprising a package housing having a housing lip and connector having a center pin abutting along a bottom surface of the housing lip. For signal registration of a first substrate to the signal lead, the substrate is âfloatedâ up to the housing lip, which provides an alignment reference to ensure that the top surface of the first substrate is aligned and in direct registration with the signal lead. In another embodiment, the center pin to substrate registration is provided at a top surface of a housing base. The housing base preferably comprises a first portion of a first height and a second portion of a second height. Accordingly, the housing base can accommodate substrates of different thickness while allowing a top surface of the first and a second substrate to be coplanar to facilitate signal registration there between.
Tao Pan - San Jose CA, US Richard E. Demaray - Portola Valley CA, US Yu Chen - San Jose CA, US Yong Jin Xie - Cupertino CA, US Rajiv Pethe - San Jose CA, US
International Classification:
C23C014/34
US Classification:
20419212, 4272481, 427259, 427282
Abstract:
A process for forming a mode size converter with an out-of-plane taper formed during deposition with a shadow mask is disclosed. Mode-size converters according to the present invention can have any number of configurations. Measured coupling efficiencies for waveguides with mode size converters according to the present invention show marked improvement.
Methods Of Treating Neoplasia With Combination Of Target-Cell Specific Adenovirus, Chemotherapy And Radiation
Yu Chen - Cupertino CA, US Daniel R. Henderson - Palo Alto CA, US
Assignee:
Cell Genesys, Inc. - Foster City CA
International Classification:
A01N063/00 A61K048/00 C12N015/861
US Classification:
424 932, 435455, 435456, 4353201
Abstract:
The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.
Methods Of Treating Neoplasia With Combinations Of Target Cell-Specific Adenovirus And Chemotherapy
Yu Chen - Cupertino CA, US Daniel R. Henderson - Palo Alto CA, US
Assignee:
Cell Genesys, Inc. - South San Francisco CA
International Classification:
A01N 63/00 A61K 48/00
US Classification:
424 932
Abstract:
The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.
William J. Yeager - Menlo Park CA, US Yu Chen - San Jose CA, US Brian K. Raymor - Arlington VA, US Jackson Wong - Menlo Park CA, US
Assignee:
Sun Microsystems, Inc. - Menlo Park CA
International Classification:
H04L 9/32
US Classification:
713175, 713153, 713168
Abstract:
A method for securing a communication between a peer node and an intermediary peer node in a peer-to-peer network comprises the peer node generating a secured communication request to the intermediary peer node. The intermediary peer node authenticates the peer node in response to the secured communication request. The intermediary peer node issues a signed certificate of authority upon successful authentication.
Joerg Rockenberger - San Jose CA, US Yu Chen - Pearland TX, US Fabio Zürcher - Brisbane CA, US Scott Haubrich - Albuquerque NM, US
Assignee:
Kovio, Inc. - Milpitas CA
International Classification:
H01L 21/44 H01L 21/4763
US Classification:
438674, 438622, 438637, 257E21273
Abstract:
Metal ink compositions, methods of forming such compositions, and methods of forming conductive layers are disclosed. The ink composition includes a bulk metal, a transition metal source, and an organic solvent. The transition metal source may be a transition metal capable of forming a silicide, in an amount providing from 0. 01 to 50 at. % of the transition metal relative to the bulk metal. Conductive structures may be made using such ink compositions by forming a silicon-containing layer on a substrate, printing a metal ink composition on the silicon-containing layer, and curing the composition. The metal inks of the present invention have high conductivity and form low resistivity contacts with silicon, and reduce the number of inks and printing steps needed to fabricate integrated circuits.
Name / Title
Company / Classification
Phones & Addresses
Yu Chen President
UCP Biosciences, Inc. Medical Devices
1445 Koll Cir, San Jose, CA 95101 10511 John Way, Cupertino, CA 95014
Yu Xuan Chen President
PENINSULA TABLE TENNIS CLUB INC Ret Sporting Goods/Bicycles
1299 Bayshore Hwy #100, Burlingame, CA 94010 6503473280
Yu Pao Chen President
ROTA AMERICA, INC Ret Mail-Order House
1460 Tully Rd STE 606, San Jose, CA 95122 4082886684
Yu Hsuan Chen President
WU AND CHEN FAMILY FOUNDATION Civic/Social Association
20437 Gln Brae Ct, Saratoga, CA 95070 994 Brackett Way, Santa Clara, CA 95054
Yu Zhong Chen President
JOE CHEN TRUCKING, INC Local Trucking Operator
1098 Cumberland Ave, San Leandro, CA 94579
Yu Chen Director
Eagle Nebula Inc
Yu X. Chen Principal
Pacific Building Construction Single-Family House Construction
1350 Pacific Ave, San Leandro, CA 94577
Yu Hong Chen Manager
HONG DA LLC
7682 E Fledgling Dr, Scottsdale, AZ 85255 3136 W Pollack St, Phoenix, AZ 85041
Jun 2012 to Jun 2012 Postdoctoral AssociateWayne State University
Sep 2005 to May 2012 Research AssistantUniversity of Windsor
Sep 2003 to Aug 2005 Research AssistantShenyang Research Institute of Chemical Industry
Aug 2002 to Aug 2003 Assistant Engineer
Education:
Wayne State University Detroit, MI Sep 2005 to May 2012 Ph. D. in Analytical ChemistryUniversity of Windsor 2003 to 2005 M.S in Physical ChemistryDalian University of Technology Dalian, CN 1998 to 2002 B.Eng in Applied Chemistry
Skills:
1. In-depth knowledge and hands-on experience in identification, characterization, and quantification of small molecules and proteins using mass spectrometry 2. Adept at top-down (middle-down) MS/MS analysis of protein post-translational modifications, using CID, ECD, ETD, and IRMPD techniques for protein fragmentation, and database searching for PTM mapping 3. Hands-on experience in sample preparation, including cell growth, harvesting, digestion, and peptide/protein separation using RP-HPLC, nano-LC, and HILIC 4. Practical knowledge H/D exchange for protein structure elucidation 5. Extensive experience in development of electrospray ionization (ESI), ion funnel, multiple ion trap (quadrupole, hexapole, and octopole ) 6. Expertise in Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) 7. Hands-on experience in SIMION 8.0 simulation and Auto CAD, Autodesk Inventor software for instrument development 8. In-depth knowledge of computational chemistry/ electronic structure calculations and gas phase thermochemistry
Apr 2014 to 2000 ERP System Consultant contractorUnited Foods International USA, Inc Hayward, CA Apr 2010 to Apr 2014 IT and Operations ManagerSystem-One Co., LTD Tokyo, JP Apr 2007 to Nov 2008 System EngineerSchering-Plough China, Inc
Jul 2003 to Apr 2004 QA
Education:
Gakuin University Yokohama, JP 2008 M.S. in Computer Information ScienceEast China University of Technology and Science 2003 B.S. in Pharmaceutical
May 2012 to 2000 Financial Accountant and Budget Coordinator, Full timeAZ Sourcing, LLC Scottsdale, AZ Sep 2011 to Apr 2012 Marketing and AccountingNational Endowment for Financial Education Denver, CO Apr 2011 to Aug 2011 Strategic Programs and Alliances, InternKwik Car Wash Denver, CO Sep 2010 to Oct 2010 Data AnalystChase Morgan Bank University Branch Denver, CO Aug 2010 to Sep 2010 VolunteerChina National Automotive Industry International Corporation
Sep 2008 to Nov 2008 Finance Department, Intern
Education:
Daniels College of Business, University of Denver Denver, CO Sep 2009 to Aug 2011 Master of Finance in RelevantBeijing Technology and Business University Hong Kong, Hong Kong Island 2010 to Dec 2010 Statistics and Financial Mathematics
Jul 2005 to Present Sr. Member of Consulting StaffBlaze DFM Inc Sunnyvale, CA Mar 2005 to Jul 2005 Member of Consulting StaffUbiTech Inc Sunnyvale, CA May 2003 to Mar 2005 Senior Technical Staff
Education:
University of California Los Angeles, CA 2003 Ph.D. in Computer ScienceZhejiang University 1998 M.S. in Computer Science and Engineering, , ChinaZhejiang University 1995 B. S. in Electrical Engineering
Montefiore Medical Center Physical Medicine 111 E 210 St STE G78, Bronx, NY 10467 7189204133 (phone), 7189202289 (fax)
Childrens Physicians Of Westchester 4350 Van Cortlandt Park E, Bronx, NY 10470 3472266437 (phone), 3472266438 (fax)
John A Coleman School 317 North St, White Plains, NY 10605 9145974071 (phone), 9143971765 (fax)
Education:
Medical School China Med Univ, Shenyang City, Liaoning, China Graduated: 1988
Procedures:
Neurological Testing Physical Medicine and Rehabilitation, Tests and Measurements Physical Therapy Evaluation
Languages:
English Spanish
Description:
Dr. Chen graduated from the China Med Univ, Shenyang City, Liaoning, China in 1988. She works in White Plains, NY and 2 other locations and specializes in Physical Medicine & Rehabilitation. Dr. Chen is affiliated with Montefiore Medical Center and Westchester Medical Center.
Dr. Chen graduated from the Taipei Med Coll, Taipei, Taiwan (385 04 Prior 1/71) in 1979. He works in Anaheim, CA and specializes in Family Medicine. Dr. Chen is affiliated with Kaiser Permanente Orange County Anaheim Medical Center.
Rush University Cancer Center 1725 W Harrison St STE 1010, Chicago, IL 60612 3129425904 (phone), 3129423192 (fax)
Education:
Medical School Albert Einstein College of Medicine at Yeshiva University Graduated: 2010
Languages:
English Polish Spanish
Description:
Dr. Chen graduated from the Albert Einstein College of Medicine at Yeshiva University in 2010. She works in Chicago, IL and specializes in Radiation Oncology. Dr. Chen is affiliated with Rush University Medical Center.