Yu Xiang Li

US Patent:

20070086975, Apr 19, 2007

Filed:

Dec 17, 2004

Appl. No.:

10/596566

Inventors:

Francis Ignatious - King of Prussia PA, US
Yu Li - Collegeville PA, US

International Classification:

A61K 31/77
A61K 31/704
A61K 31/7024
A61K 31/4745

US Classification:

424078270, 525054200, 424649000, 514034000, 514037000, 514283000

Abstract:

Disclosed are complexes of an amphiphilic copolymer, wherein the amphiphilic copolymer has benzoyl sulfonic acid groups on the hydrophobic segment of the copolymer.

US Patent:

20110014283, Jan 20, 2011

Filed:

Feb 28, 2008

Appl. No.:

12/528492

Inventors:

Allan James Clarke - Collegeville PA, US
David Geoffrey Cullingford - Essex, GB
Yu Li - Collegeville PA, US

International Classification:

A61K 9/30
A61K 31/55

US Classification:

424465, 51421701

Abstract:

The present invention relates to a novel dosage form, to a process for preparing the dosage form and to the use of the dosage form in the treatment of neurological and psychiatric disorders.

US Patent:

20110020447, Jan 27, 2011

Filed:

Feb 28, 2008

Appl. No.:

12/528490

Inventors:

Allan James Clarke - Collegeville PA, US
Ian Paul Conn - Essex, GB
Simon Richard Hicks - Essex, GB
Yu Li - Collegeville PA, US
Xiaolei Wang - Essex, GB

International Classification:

A61K 31/55
A61K 9/30
A61K 9/44
B05D 3/00
A61P 25/00

US Classification:

424467, 51421301, 424475, 427 214

Abstract:

The present invention relates to a novel dosage form, to a process for preparing the dosage form and to the use of the dosage form in the treatment of neurological and psychiatric disorders.

US Patent:

20110189280, Aug 4, 2011

Filed:

Aug 21, 2009

Appl. No.:

13/061162

Inventors:

Allan James Clarke - Collegeville PA, US
Yu Li - Collegeville PA, US
Yinka Bunmi Ogunlana - Essex, GB

International Classification:

A61K 9/30
A61K 31/551
A61K 9/36
A61P 25/28
A61P 25/00
A61P 25/18
A61P 25/16

US Classification:

424465, 424475, 514218, 424480, 427 214

Abstract:

The invention relates to a dosage form for oral administration comprising a carrier tablet, wherein the carrier tablet is at least partially (preferably partially) covered by a film comprising 1-isopropyl-4-{[4-(tetrahydro-2H-pyran-4-yloxy)phenyl]carbonyl}hexahydro-1H-1,4-diazepineor a pharmaceutically acceptable salt thereof, such as the mono-maleate salt thereof.In particular embodiments, the film, which at least partially covers the carrier tablet, comprises a stabiliser (e.g. citric acid), and/or a film former (e.g. hydroxypropylcellulose).The film is preferably present in a recess on the carrier tablet.The invention also relates to a method of producing said dosage form.