Yu U Zhang

US Patent:

7543354, Jun 9, 2009

Filed:

Nov 4, 2005

Appl. No.:

11/267687

Inventors:

Luke Lee - Belle Mead NJ, US
Yu Sheng Zhang - Stewartsville NJ, US

Assignee:

Logan Instruments Corporation - Somerset NJ

International Classification:

A46B 13/04
B08B 9/087

US Classification:

15302, 15304, 15 56

Abstract:

Brush head for cleaning a vessel and use in an automatic dissolution vessel cleaning apparatus which includes a rotatable shaft defining a through passage, an upper end of which is operatively connected to a vacuum source, an inflow housing having at least one channel through which cleaning fluid is pumped and to which the shaft is rotatably mounted, and a brush assembly mounted on the shaft below the housing such that a lower end of the passage is situated below the brush assembly. In use, when the brush head is inserted into the vessel, cleaning fluid is directed through the channel(s) into the vessel while the shaft rotates causing the brush assembly to rotate and clean an inner wall of the vessel with fluid in the vessel being drawn into the passage via its lower end upon coupling of its upper end to the vacuum source.

US Patent:

7585465, Sep 8, 2009

Filed:

Jun 15, 2006

Appl. No.:

11/453634

Inventors:

Luke Lee - Belle Mead NJ, US
Yu Sheng Zhang - Stewartsville NJ, US
Jose Castro - Garfield NJ, US

Assignee:

Logan Instruments Corp. - Somerset NJ

International Classification:

G01N 33/48
B01F 9/08
B01F 15/06

US Classification:

422 681, 422 64, 366 91, 366142, 366143, 366145, 366297, 73866

Abstract:

Pharmaceutical product release rate testing device includes a base, at least one carousel member rotatably mounted on the base, each carousel member including a plurality of test tube pockets each adapted to receive a test tube fillable with test media, and a dipping mechanism for dipping samples to be tested into the test tubes when present in the pockets and filled with test media. A rinsing/filling mechanism is provided to rinse or fill test tubes in one set of pockets while test tubes in another set of pockets are involved in the dipping process via the dipping mechanism. The carousel member is temperature-controlled such that all of the test tubes when present in the pockets are at substantially the same temperature for critical stages of the testing process. Methods for conducting pharmaceutical product release rate testing using the device are also disclosed.

US Patent:

7858192, Dec 28, 2010

Filed:

Nov 20, 2007

Appl. No.:

11/986290

Inventors:

Yu Zhang - Chatham NJ, US
Jae-Won Kim - Elmhurst NY, US
Van P. Thompson - New York NY, US

Assignee:

New York University - New York NY

International Classification:

B32B 17/06

US Classification:

428432, 428426, 428428

Abstract:

The present invention provides a functionally graded glass/ceramic/glass sandwich system especially useful in damage resistant, ceramic dental and orthopedic prosthesis. The functionally graded glass/substrate/glass composite structure comprises an outer (aesthetic) residual glass layer, a graded glass-ceramic layer, and a dense interior ceramic. The functionally graded glass/substrate/glass composite structure may further comprise a veneer on an exterior surface. The present invention also provides a method for preparing a functionally graded glass/ceramic/glass sandwich system. A powdered glass-ceramic composition or a glass tape is applied to the accessible surfaces of a dense alumina substrate to thereby substantially cover the substrate surfaces. The glass of the composition has a CTE similar to that of the substrate material. The glass-ceramic composition is infiltrated into the dense substrate by heating the assembly to temperatures 50-700 C.

US Patent:

7871706, Jan 18, 2011

Filed:

Nov 9, 2007

Appl. No.:

11/983815

Inventors:

Yu Zhang - Chatham NJ, US
Jae-Won Kim - Elmhurst NY, US

Assignee:

New York University - New York NY

International Classification:

B32B 17/06

US Classification:

428432, 428426, 428428

Abstract:

The present invention provides a functionally graded glass/ceramic/glass sandwich system for use in damage resistant, ceramic and orthopedic prosthesis. The functionally graded glass/substrate/glass composite structure comprises an outer residual glass layer, a graded glass-ceramic layer, and a dense interior ceramic. The functionally graded glass/substrate/glass composite structure may further comprise a veneer on an exterior surface. The present invention also provides a method for preparing a functionally graded glass/ceramic/glass sandwich system. A powdered glass-ceramic composition is applied to the accessible surfaces of a presintered zirconia substrate to thereby substantially cover the substrate surfaces. The glass of the composition has a CTE similar to that of the substrate material. The glass-ceramic composition is infiltrated into and densifies the substrate by heating the assembly to at least the sintering temperature of the substrate.

US Patent:

20090118114, May 7, 2009

Filed:

Sep 22, 2008

Appl. No.:

12/284620

Inventors:

Yu Zhang - Chatham NJ, US
Racquel Regeros - New York NY, US
Jae-Won Kim - Elmhurst NY, US

International Classification:

C04B 35/053

US Classification:

501135

Abstract:

The present invention provides a functionally graded bioactive glass/ceramic composite structure or bioactive glass/ceramic/bioactive glass sandwich structure for use in such applications as damage resistant, ceramic dental implants, immediate tooth replacement, endodontic posts, orthopedic prostheses, orthopedic stems, bone substitutes, bone screws, plates, and anchors, nonunion fractures repair, alveolar ridge augmentation, missing small bone parts (e.g. fingers, toes, etc), maxilla facial reconstruction, spinal fusion, and scaffolds for bone regeneration, comprising a residual bioactive glass or glass-ceramic layer at all accessible surfaces, followed by an underlying graded glass-ceramic layer, and then an dense interior ceramic. The residual bioactive glass or glass-ceramic layer can be further transformed to a carbonate apatite (CHA) layer by immersing in calcifying solution or simulated body fluid (SBF) with electrolyte composition similar to that of serum. The interior ceramic preferably contains yttria-tetragonal zirconia polycrystal (Y-TZP) or ceria stabilized tetragonal zirconia polycrystal (Ce-TZP) or magnesia stabilized zirconia (Mg-PSZ) or calcia stabilized zirconia (Ca-PSZ) or alumina or zirconia-alumina composites. Further, the invention provides methods for making the same functionally graded bioactive glass/ceramic composite structure or graded bioactive glass/ceramic/bioactive glass sandwich structure.

US Patent:

20110070452, Mar 24, 2011

Filed:

Nov 18, 2010

Appl. No.:

12/927586

Inventors:

Yu Zhang - Chatham NJ, US
Jae-Won Kim - Elmhurst NY, US

International Classification:

B32B 17/06
B05D 3/02
B05D 3/06

US Classification:

428432, 427193, 4273762, 427559

Abstract:

The present invention provides a functionally graded glass/ceramic/glass sandwich system for use in damage resistant, ceramic and orthopedic prosthesis. The functionally graded glass/substrate/glass composite structure comprises an outer residual glass layer, a graded glass-ceramic layer, and a dense interior ceramic. The functionally graded glass/substrate/glass composite structure may further comprise a veneer on an exterior surface. The present invention also provides a method for preparing a functionally graded glass/ceramic/glass sandwich system. A powdered glass-ceramic composition is applied to the accessible surfaces of a presintered zirconia substrate to thereby substantially cover the substrate surfaces. The glass of the composition has a CTE similar to that of the substrate material. The glass-ceramic composition is infiltrated into and densifies the substrate by heating the assembly to at least the sintering temperature of the substrate.

US Patent:

20110120214, May 26, 2011

Filed:

Nov 23, 2009

Appl. No.:

12/623763

Inventors:

Luke Lee - Belle Mead NJ, US
Yu Sheng Zhang - Stewartsville NJ, US
Jose Castro - Garfield NJ, US

Assignee:

Logan Instruments Corp. - Somerset NJ

International Classification:

G01N 13/04

US Classification:

73 6447

Abstract:

Vessel for transdermal diffusion cell testing includes a container defining an interior chamber having an opening against which skin is placed, and a casing arranged partially around and spaced apart from part of the container to define a compartment therebetween. The chamber retains a saline solution and is not in flow communication with the compartment through which water is circulated. The vessel includes separate inlet ports and outlet ports, each including a conduit communicating with the chamber or compartment. The outlet port of the chamber is arranged above the inlet port of the chamber, proximate the opening of the chamber, and is angled downward relative to a horizontal upper surface of the container against which skin being tested is placed. Tilting of the vessel prior to or during introduction of solution prevents air bubbles from remaining between the skin and the solution.

US Patent:

20110123956, May 26, 2011

Filed:

Nov 8, 2010

Appl. No.:

12/927137

Inventors:

Yu Zhang - Chatham NJ, US
Jae-Won Kim - Elmhurst NY, US
Van P. Thompson - New York NY, US

International Classification:

A61C 13/08
B32B 17/06
A61L 27/30

US Classification:

4332011, 428426, 428432, 4332121, 427 227

Abstract:

The present invention provides a functionally graded glass/ceramic/glass sandwich system especially useful in damage resistant, ceramic dental and orthopedic prosthesis. The functionally graded glass/substrate/glass composite structure comprises an outer (aesthetic) residual glass layer, a graded glass-ceramic layer, and a dense interior ceramic. The functionally graded glass/substrate/glass composite structure may further comprise a veneer on an exterior surface. The present invention also provides a method for preparing a functionally graded glass/ceramic/glass sandwich system. A powdered glass-ceramic composition or a glass tape is applied to the accessible surfaces of a dense alumina substrate to thereby substantially cover the substrate surfaces. The glass of the composition has a CTE similar to that of the substrate material. The glass-ceramic composition is infiltrated into the dense substrate by heating the assembly to temperatures 50-700 C. below the sintering temperature of the substrate.