Yuling Li

US Patent:

8198245, Jun 12, 2012

Filed:

Jul 24, 2008

Appl. No.:

12/220420

Inventors:

Laura Niklason - Greenwich CT, US
Yuling Li - Chapel Hill NC, US
Juliana Blum - Raleigh NC, US
Shannon Dahl - Durham NC, US
Geoffrey Erickson - Westport CT, US
Frank Zeigler - Encinitas CA, US

Assignee:

Humacyte, Inc. - Research Triangle Park NC

International Classification:

A61K 38/39
A61K 31/726
A61K 38/18
C07K 14/78

US Classification:

514 188, 514 76, 424 937, 530353, 530356

Abstract:

The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.

US Patent:

20090319033, Dec 24, 2009

Filed:

Mar 7, 2007

Appl. No.:

12/281434

Inventors:

Laura E Niklason - Greenwich CT, US
Yuling Li - Chapel Hill NC, US

Assignee:

Humacyte - Durham NC

International Classification:

A61F 2/06
C12N 5/06
G01N 33/53
C12N 5/08

US Classification:

623 141, 435381, 435 72, 435366

Abstract:

Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the isolation and purification of endothelial cells using purified enzymes and antibody-based selection. The cells can be obtained from liposuction procedures and used in vascular grafts.

US Patent:

20110020271, Jan 27, 2011

Filed:

May 20, 2010

Appl. No.:

12/784235

Inventors:

Laura E. Niklason - Greenwich CT, US
Yuling Li - Chapel Hill NC, US
Heather Prichard - Raleigh NC, US
Shannon Dahl - Durham NC, US
Juliana Blum - Raleigh NC, US

Assignee:

Humacyte, Inc. - Research Triangle Park NC

International Classification:

A61K 38/20
A61K 38/39
A61K 35/12
A61K 38/18
A61K 38/19
A61K 38/21
A61P 43/00
A61P 29/00
A61P 23/00
A61P 39/06
A61P 17/10
A61Q 19/00

US Classification:

424 852, 514 11, 424 937, 514 89, 514 82, 514 85, 424 851, 424 854, 514 84, 514 96, 514 91, 514 77, 514 88

Abstract:

The present invention provides compositions comprising isolated elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.

US Patent:

20120230950, Sep 13, 2012

Filed:

May 21, 2012

Appl. No.:

13/476406

Inventors:

Laura Niklason - Greenwich CT, US
Yuling Li - Chapel Hill NC, US
Juliana Blum - Raleigh NC, US
Shannon Dahl - Durham NC, US
Geoffrey Erickson - Westport CT, US
Frank Zeigler - Encinitas CA, US

Assignee:

Humacyte, Inc. - Morrisville NC

International Classification:

A61K 38/39
A61K 35/36
A61K 38/18
A61K 38/19
B65D 65/00
A61K 38/21
A61P 17/00
A61P 27/00
A61P 17/10
A61P 17/02
A61K 35/12
A61K 38/20

US Classification:

424 852, 514 11, 424574, 424 937, 514 96, 514 89, 514 82, 514 91, 514 135, 514 85, 424 851, 514 84, 424 854, 514 77, 514 2192, 514 188, 206571

Abstract:

The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.