Yunqi Zhang

US Patent:

20130330721, Dec 12, 2013

Filed:

Mar 29, 2013

Appl. No.:

13/854003

Inventors:

Yunqi Zhang - Gaithersburg MD, US

Assignee:

Creatv MicroTech, Inc. - Potomac MD

International Classification:

G01N 1/40
B01D 29/00

US Classification:

435 611, 210490, 210767, 29428, 4352871, 435 71, 435 34, 435 39, 435325

Abstract:

A microfilter comprising a polymer layer formed from photo-definable dry film, and a plurality of apertures each extending through the polymer layer. A microfilter comprising two or more polymer layers formed from photo-definable dry film, and a plurality of apertures or open areas each extending through the polymer layer. Methods of forming apertures in one or more layers of photo-definable dry film are also disclosed. Filter holder designs and methods appropriate to hold microfilters to collect the rare cells and to perform of assays in the filter holder are provided. Microfiltration chip designs and methods appropriate to collect the rare cells and to perform assays in the microfluidic chips are provided. The invention also describes the use of the microfilter, filter holder and microfilter chips to collect rare cells from body fluids and perform assays, and these rare cells can be used for medical and biological research applications.

US Patent:

20140322743, Oct 30, 2014

Filed:

Nov 21, 2012

Appl. No.:

14/359467

Inventors:

- Potomac MD, US
Yunqi Zhang - Gaithersburg MD, US

Assignee:

Creatv Microtech, Inc. - Potomac MD

International Classification:

G01N 33/50
B01D 39/16
B01L 3/00
B01L 9/00

US Classification:

435 29, 2952511, 4274071, 422560, 422534, 422547, 430320

Abstract:

A microfilter comprising a polymer layer formed from epoxy-based photo-definable dry film, and a plurality of apertures each extending through the polymer layer. A microfilter comprising two or more polymer layers formed from epoxy-based photo-definable dry film, and a plurality of apertures or open areas each extending through the polymer layer. A method of forming a microfilter is also disclosed. The method includes providing a first layer of epoxy-based photo-definable dry film disposed on a substrate, exposing the first layer to energy through a mask to form a pattern, defined by the mask, in the first layer of dry film, forming, from the exposed first layer of dry film, a polymer layer having a plurality of apertures extending therethrough, the plurality of apertures having a distribution defined by the pattern, and removing the polymer layer from the substrate. Unique filter holder designs and methods appropriate to hold microfilters to collect the rare cells and allow performing assays in the filter holder are provided. The invention also describes the use of the microfilter and filter holder to collect rare cells from body fluids and perform assays. Rare cells collected on the microfilter in accordance with embodiments of the present invention can be used for medical and biological research applications.

US Patent:

20140132734, May 15, 2014

Filed:

Nov 12, 2012

Appl. No.:

13/674715

Inventors:

Ping Zhuang - North Potomac MD, US
Yunqi Zhang - Gaithersburg MD, US

Assignee:

Spatial Intergrated Sytems, Inc. - Gaithersburg MD

International Classification:

H04N 13/02

US Classification:

348 47

Abstract:

A moving object to be subject to 3-dimensional rendering is illuminated by a repeated sequence of a number N different two-dimensional structured light patterns. For each illumination, the illuminated object is captured by two spaced apart cameras, thereby creating a series of pairs of two-dimensional images. A set of N adjacent pairs of the two-dimensional images is used to form a single three-dimensional image frame. A moving window of N adjacent pairs of the two-dimensional images provides a train of such three-dimensional image frames. The object may furthered be illuminated by non-structured light whose captured image reflection may be used as an overlay over the three-dimensional rendered object.