Zhong P Li

US Patent:

20040219567, Nov 4, 2004

Filed:

Nov 5, 2003

Appl. No.:

10/703063

Inventors:

Andrea Califano - New York NY, US
Aristidis Floratos - Astoria NY, US
Zhong Li - Rutherford NJ, US
David Wang - Kildeere IL, US

International Classification:

C12Q001/68
G06F019/00
G01N033/48
G01N033/50

US Classification:

435/006000, 702/020000

Abstract:

A pattern discovery-based method for identifying genetic associations in mapping complex traits. In one embodiment, this invention describes the applicable study designs, the pattern discovery algorithm on phenotypic/genotypic data, and methods to evaluate statistical significance of identified patterns. Patterns identified through the proposed methods act as signatures or profiles that can be used to locate genes or genomic regions responsible for the traits of interests in the genome. This invention has been successfully applied to two independent datasets collected from actual genetic studies and has produced significant results.

US Patent:

20090254588, Oct 8, 2009

Filed:

Jun 19, 2007

Appl. No.:

11/764958

Inventors:

Zhong Li - Livingston NJ, US

International Classification:

G06F 17/30

US Classification:

707201, 707E17007

Abstract:

The invention is directed to a system and method for merging at least two datasets each having at least two keys and each having a plurality of data elements. The system determines a quantity of shared data elements in each dataset for each key as well as a quantity of unique data elements in each dataset for each key. The system then generates a graphical output representing the quantity of shared and unique data elements in each dataset for each key. The system receives a selection input selecting one of a plurality of merge strategies. Each merge strategy is based on the quantity shared or unique data elements in each dataset for each key. The system then generates a merged dataset containing data elements from the at least two datasets based on the at least two keys and the selected merge strategy.

US Patent:

20170342472, Nov 30, 2017

Filed:

Aug 10, 2017

Appl. No.:

15/673634

Inventors:

Zhong LI - Short Hills NJ, US

International Classification:

C12Q 1/68
B82Y 5/00
G01N 33/543
B82Y 15/00

Abstract:

The present invention relates to a novel method for detecting instantaneously a biomarker immobilized to a solid surface and related uses. The method comprises exposing the biomarker to a probe having a magnetic label in a solution; applying a magnetic field to the solution, whereby a complex of the biomarker and the probe is formed on the solid surface; withdrawing the magnetic field; removing the solution from the solid surface; and detecting the complex instantaneously, wherein the presence of the complex on the solid surface indicates the presence of the biomarker.

US Patent:

20150275281, Oct 1, 2015

Filed:

May 30, 2013

Appl. No.:

14/548940

Inventors:

Zhong Li - , US
Zhong Li - Short Hills NJ, US

International Classification:

C12Q 1/68

Abstract:

The present invention relates to a novel method for detecting instantaneously a biomarker immobilized to a solid surface and related uses. The method comprises exposing the biomarker to a probe having a magnetic label in a solution; applying a magnetic field to the solution, whereby a complex of the biomarker and the probe is formed on the solid surface; withdrawing the magnetic field; removing the solution from the solid surface; and detecting the complex instantaneously, wherein the presence of the complex on the solid surface indicates the presence of the biomarker.