Bharat M Mehta

US Patent:

20130177643, Jul 11, 2013

Filed:

Jan 4, 2013

Appl. No.:

13/734846

Inventors:

Chrysalis Pharma AG - Sachseln, CH
Bharat M. MEHTA - Mendham NJ, US
Gerald L. WISLER - Windermere FL, US
Michael H. DAVIDSON - Highland Park IL, US
Peter Ralph WOOD - Cotherstone, GB

Assignee:

Chrysalis Pharma AG - Sachseln
Omthera Pharmaceuticals, Inc. - Princeton NJ

International Classification:

A61K 31/202
A61K 31/366

US Classification:

424456, 514560, 514460

Abstract:

DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented.

US Patent:

20130209556, Aug 15, 2013

Filed:

Mar 12, 2013

Appl. No.:

13/797557

Inventors:

Chrysalis Pharma AG - , US
Bharat M. MEHTA - Mendham NJ, US
Gerald L. WISLER - Windermere FL, US
Michael H. DAVIDSON - Highland Park IL, US
Peter Ralph WOOD - Cotherstone, GB

Assignee:

Chrysalis Pharma AG - Sachseln
Omthera Pharmaceuticals, Inc. - Princeton NJ

International Classification:

A61K 31/202

US Classification:

424456, 514560, 424451

Abstract:

DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented.

US Patent:

20130295173, Nov 7, 2013

Filed:

May 7, 2013

Appl. No.:

13/889202

Inventors:

Timothy J. Maines - Potomac MD, US
Bharat M. Mehta - Mendham NJ, US
Michael H. Davidson - Highland Park IL, US

International Classification:

A61K 31/505
A61K 31/22
A61K 31/366
A61K 31/47
A61K 31/202
A61K 31/40

US Classification:

424463, 514275, 514423, 514460, 514311, 514548

Abstract:

The present disclosure provides pharmaceutical compositions of statins and polyunsaturated fatty acids (PUFAs), in which the statins are dissolved in the PUFAs, the PUFA species being present substantially in the free acid form. Also provided are oral unit dosage forms of the disclosed pharmaceutical compositions and methods of treating blood lipid disorders using the compositions and oral unit dosage forms.

US Patent:

20190029985, Jan 31, 2019

Filed:

Oct 3, 2018

Appl. No.:

16/150363

Inventors:

- Wilmington DE, US
- Sachseln, CH
Bharat M. MEHTA - Mendham NJ, US
Gerald L. WISLER - Windermere FL, US
Michael H. DAVIDSON - Highland Park IL, US
Peter Ralph WOOD - Cotherstone, GB

International Classification:

A61K 31/202
A61K 9/48
A61K 31/366
A61K 45/06

Abstract:

DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented.

US Patent:

20150320715, Nov 12, 2015

Filed:

Apr 29, 2015

Appl. No.:

14/699556

Inventors:

- Princeton NJ, US
- Sachseln, CH
Bharat M. MEHTA - Mendham NJ, US
Gerald L. WISLER - Windermere FL, US
Michael H. DAVIDSON - Highland Park IL, US
Peter Ralph WOOD - Cotherstone, GB

International Classification:

A61K 31/202

Abstract:

DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented.

US Patent:

20150104504, Apr 16, 2015

Filed:

May 7, 2013

Appl. No.:

14/399355

Inventors:

- Princeton NJ, US
Timothy J. Maines - Potomac MD, US
Michael H. Davidson - Highland Park IL, US
Bharat M. Mehta - Mendham NJ, US

International Classification:

A61K 47/12
A61K 31/505
A61K 9/48
A61K 31/47
A61K 31/22
A61K 31/40
A61K 31/366

US Classification:

424452, 514423, 514275, 514460, 514311, 514510

Abstract:

The present disclosure provides pharmaceutical compositions of statins and polyunsaturated fatty acids (PUFAs), in which the statins are dissolved in the PUFAs, the PUFA species being present substantially in the free acid form. Also provided are oral unit dosage forms of the disclosed pharmaceutical compositions and methods of treating blood lipid disorders using the compositions and oral unit dosage forms.

US Patent:

20150004224, Jan 1, 2015

Filed:

Jan 4, 2013

Appl. No.:

14/370730

Inventors:

- Princeton NJ, US
- Sachseln, CH
Bharat M. Mehta - Mendham NJ, US
Gerald Wisler - Windermere FL, US
Michael Davidson - Highland Park IL, US
Peter Ralph Wood - Cotherstone, GB

International Classification:

A61K 31/202
A61K 45/06
A61K 9/48

US Classification:

424452, 514560, 424451, 424456

Abstract:

DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented. Also provided are methods of treating hypertriglyceridemia (200 mg/dL-500 mg/dL) by adjunctive administration of a statin and the pharmaceutical compositions described herein. Further treatment methods include, inter alia, treatments to increase plasma EPA:AA ratios, treatments to decrease ApoCIII levels, and treatments to reduce or prevent resistance to platelet aggregation inhibitors.