David S Sharp

US Patent:

20130022667, Jan 24, 2013

Filed:

Jul 19, 2012

Appl. No.:

13/553155

Inventors:

David J. Sharp - Scarsdale NY, US
Rabab Charafeddine - Bronx NY, US

International Classification:

A61K 31/713
C12Q 1/04
A61K 9/127
C07H 21/02
A61P 17/02
A61K 9/50

US Classification:

424450, 514 44 A, 424490, 536 245, 435 34

Abstract:

Methods of treating a wound in a subject are provided comprising administering to the subject an amount of an inhibitor of Fidgetin-like 2. Compositions and pharmaceutical compositions comprising an amount of an inhibitor of Fidgetin-like 2 are also provided. Methods are also provided for identifying an inhibitor of Fidgetin-like 2.

US Patent:

20130192640, Aug 1, 2013

Filed:

Jan 26, 2012

Appl. No.:

13/359159

Inventors:

Neal G. Skinner - Lewisville TX, US
Etienne M. Samson - Cypress TX, US
David P. Sharp - Houston TX, US
Michel LeBlanc - Houston TX, US

International Classification:

B08B 9/032

US Classification:

134 18, 134 2211, 134 21, 134 19, 134166 C, 134105, 15320

Abstract:

According to one embodiment, the disclosure provides a system for removal of deleterious chemicals from a fiber optic line. The system may a fiber optic line having two ends, an outer tube, an optical fiber, and an inner volume, a fluid operable to move through the inner volume, the fluid operable to remove at least one deleterious chemical other than hydrogen from the fiber optic line, and a fluid controller connected to at least one end of the fiber optic line and operable to control movement of the fluid through the inner volume. According to another embodiment, the disclosure provides a method of removing a deleterious chemical from a fiber optic line. According to a third embodiment, the disclosure provides a method of removing a deleterious chemical from a fiber optic line by introducing a vacuum in an inner volume of a sealed fiber optic line in a static or cyclical manner.

US Patent:

56673469, Sep 16, 1997

Filed:

Feb 6, 1996

Appl. No.:

8/597606

Inventors:

David L. Sharp - New York NY

International Classification:

F16B 3102

US Classification:

411 10

Abstract:

A pre-load indicating washer for properly tensioning a joint held together by an externally threaded member and an internally threaded member. The pre-load indicating washer has a plurality of protuberances, struck and partially sheared from the annular body of the washer, which are pushed under load back into a corresponding number of indentations in the annular body which are formed when the protuberances are formed. The protuberances of the pre-load indicating washer are curved in outline with no portion of the protuberances extending radially outward beyond the outer periphery of the bearing surface of an externally threaded member when the pre-load indicating washer is positioned adjacent the externally threaded member, or radially outward beyond the outer periphery of the bearing surface of an internally threaded member when the pre-load indicating washer is positioned adjacent the internally threaded member.

US Patent:

20200296167, Sep 17, 2020

Filed:

May 14, 2020

Appl. No.:

16/874572

Inventors:

- Boulder CO, US
Alin COSMANESCU - Tenafly NJ, US
Sean SCHUMER - New York NY, US
Stanley OKRASINSKI - New York NY, US
Andrew TERGIS - New York NY, US
Kristin SALOMON - New York NY, US
Edward BEAR - New York NY, US
Julio LIRIANO - Fort Lee NJ, US
David NEWTON - Rye NY, US
John PERKINS - Tallahassee FL, US
David SHARP - New York NY, US
Sameer MORE - New York NY, US
Paul ROTHMAN - Brooklyn NY, US

International Classification:

H04L 29/08
H04L 12/24
H04L 29/06

Abstract:

In some embodiments, an electronic and digital building block system includes modular electronic building modules that can be electrically coupled together to create various different electronic devices. In addition to physical electronic modules, the system can include digital building blocks to further enhance and integrate the functions of an assembled bit-system that can be created/assembled by a user of the block electronic building system. The digital building blocks are not a physical module, but digital content or other software or cloud applications that can be represented as virtual digital blocks, and that can interface with the physical modules. The digital blocks can provide integration between the functionality of the physical building blocks and functionality of computer-based and/or web-based applications, programs and systems. The electronic and digital building block system can include a system program and a visualizer that can be viewed on the display of a computer device.

US Patent:

20190017049, Jan 17, 2019

Filed:

Sep 27, 2018

Appl. No.:

16/143651

Inventors:

- Bronx NY, US
David Sharp - Scarsdale NY, US

Assignee:

ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. - Bronx NY

International Classification:

C12N 15/113
C07K 14/47

Abstract:

Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kifl9 and Cep192. Methods and compositions are provided for enhancing wound healing, treating fibrosis, reducing scarring and treating nerve pain.

US Patent:

20160237428, Aug 18, 2016

Filed:

Sep 12, 2014

Appl. No.:

15/023869

Inventors:

- Bronx NY, US
David Sharp - Scarsdale NY, US

Assignee:

Albert Einstein College of Medicine, inc. - Bronx NY

International Classification:

C12N 15/113

Abstract:

Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kif19 and Cep192. Methods and compositions are provided for enhancing wound healing, treating fibrosis, reducing scarring and treating nerve pain.