Kevin C Sheehan

US Patent:

6403378, Jun 11, 2002

Filed:

Apr 26, 2001

Appl. No.:

09/844789

Inventors:

Don F. Rackham - Palo Alto CA
Kevin M. Sheehan - Palo Alto CA

Assignee:

Guava Technologies, Inc. - Burlingame CA

International Classification:

G01N 3100

US Classification:

436 10, 436 8, 436 63, 436164, 436166, 436172, 435 29, 2524081

Abstract:

A kit for labeling cells to determine their viability which includes a first dye for labeling non-viable cells and a second dye for labeling all cells, including non-viable cells in which the dyes are selected to have concentrations suitable for determining the viability of cells in cell suspensions having different cell viability.

US Patent:

6854072, Feb 8, 2005

Filed:

Jun 6, 2001

Appl. No.:

09/874249

Inventors:

Robert Penn Cagle - Claremont CA, US
Patrick J. McEvoy - Palo Alto CA, US
Kevin Sean Sheehan - Sunnyvale CA, US

Assignee:

Continuous Computing Corporation - San Diego CA

International Classification:

G06F011/00
G06F015/16

US Classification:

714 15, 714 1, 714 6, 709203

Abstract:

A system and method for providing highly available and/or fault tolerant servers by implementing a lookup table or other data structure that allows a common file handle to be generated and interpreted by any component server of the HA server, thereby preventing stale file handles and removing local file system requirements as to media, implementation, and location.

US Patent:

20050289152, Dec 29, 2005

Filed:

Jun 10, 2004

Appl. No.:

10/866229

Inventors:

William Earl - Boulder Creek CA, US
Chetan Rai - Palo Alto CA, US
Kevin Sheehan - Palo Alto CA, US
Patrick Stirling - Oakland CA, US
Brian Byrnes - Mountain View CA, US
Tomasz Barszczak - Fremont CA, US

International Classification:

G06F017/00

US Classification:

707100000

Abstract:

A system and method for efficiently implementing a local or distributed file system is disclosed. The system may include a distributed virtual file system (“dVFS”) that utilizes a persistent intent log (“PIL”) to record transactions to be applied to the file system. The PIL is preferably implemented in stable storage, so that a logical operation may be considered complete as soon as the log record has been made stable. This allows the dVFS to continue immediately, without waiting for the operation to be applied to a local or real file system. The dVFS may further incorporate replication to one or more remote file systems as an integral facility.

US Patent:

20060236071, Oct 19, 2006

Filed:

Apr 15, 2005

Appl. No.:

11/106857

Inventors:

Tomasz Barszczak - Fremont CA, US
Kevin Sheehan - Palo Alto CA, US
Chetan Rai - Palo Alto CA, US

International Classification:

G06F 9/34

US Classification:

711204000, 717151000, 717152000, 717161000

Abstract:

A method and system for managing operation streams for multiple memory devices is presented. The method determines cross-dependencies among multiple operations and uses the cross-dependencies to optimize the execution of the operations. Also presented is a method of synchronizing memory devices with little adverse effects on system operations. The method entails sampling the objects in a predetermined order. Since the system is in normal use while the sampling is happening, an operation is received to be performed on at least one target object. A state of the target object is determined. If the target object is in a revising state, revision is performed on the second storage system and the operation is applied to the target object but its application to the second memory device is deferred until the target object is in its final state.

US Patent:

51426803, Aug 25, 1992

Filed:

Apr 26, 1989

Appl. No.:

7/343843

Inventors:

Tadd V. Ottman - Fremont CA
Kevin S. Sheehan - Mountain View CA
Denis T. Flagg - Alto CA

Assignee:

Sun Microsystems, Inc. - Mountain View CA

International Classification:

G06F 9445
G06F 1516

US Classification:

395700

Abstract:

The method allows for the loading of operating systems between computers over a network, thereby drastically decreasing the amount of time required to download an operating system or update an operating system. A root directory is created and a subset of the operating system is loaded into the memory of the computer which is to receive the operating system, thereby eliminating the need to access or use the disk during the operating system download process. The subset of the operating system contains the basic commands for file creation and manipulation, directory creation and network communication. The computer system is then started using the subset of the operating system located in memory and connected to the network. Once the computer is connected to the network, the files comprising the operating system to be downloaded are copied and transferred from a remote computer over the network and stored on the disk drive of the receiving computer.

US Patent:

20210244763, Aug 12, 2021

Filed:

Nov 6, 2020

Appl. No.:

17/091363

Inventors:

- Menlo Park CA, US
Nathaniel Fernhoff - Menlo Park CA, US
Kevin Sheehan - Menlo Park CA, US

International Classification:

A61K 35/17
C12N 5/0783
C12N 5/0789
A61P 37/02
A61P 3/00
A61P 7/06
A61P 21/00
A61P 35/02
C12N 5/00

Abstract:

The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.

US Patent:

20190298773, Oct 3, 2019

Filed:

Apr 18, 2019

Appl. No.:

16/388095

Inventors:

- Menlo Park CA, US
Nathaniel Fernhoff - Menlo Park CA, US
Kevin Sheehan - Menlo Park CA, US

International Classification:

A61K 35/17
C12N 5/0783
C12N 5/0789
C12N 5/00
A61P 21/00
A61P 7/06
A61P 3/00
A61P 37/02
A61P 35/02

Abstract:

The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.

US Patent:

20180264039, Sep 20, 2018

Filed:

Mar 15, 2018

Appl. No.:

15/922709

Inventors:

- Menlo Park CA, US
Nathaniel Fernhoff - Menlo Park CA, US
Kevin Sheehan - Menlo Park CA, US

International Classification:

A61K 35/17
C12N 5/0783
C12N 5/0789

Abstract:

The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.