Mladen Alan Vouk

US Patent:

20030073078, Apr 17, 2003

Filed:

Jul 13, 2001

Appl. No.:

09/905289

Inventors:

David Rosnick - Raleigh NC, US
Donald Bitzer - Cary NC, US
Mladen Vouk - Cary NC, US

International Classification:

C12Q001/68
G06F019/00
G01N033/48
G01N033/50

US Classification:

435/006000, 702/020000

Abstract:

Computer-based methods are useful for screening a nucleic acid sequence for efficient translation in a predetermined host. These methods involve providing a 3′-end terminal ribosomal nucleic acid (rRNA) sequence, providing a substrate nucleic acid sequence, and detecting the presence or absence of a three-base binding strength (i.e., binding energy) periodic cycle and/or phase between the ribosomal nucleic acid sequence and the substrate nucleic acid sequence through the substrate nucleic acid sequence. The presence of the three base periodic binding strength cycle and/or correct phase through the substrate nucleic acid sequence indicates that the substrate nucleic acid sequence is a candidate for efficient translation in the host.

US Patent:

53814258, Jan 10, 1995

Filed:

Mar 27, 1992

Appl. No.:

7/858713

Inventors:

Donald L. Bitzer - Urbana IL
Mladen A. Vouk - Cary NC
Vijay Srinivasan - Cary NC
Sunny K. Lo - Raleigh NC
Ajay Dholakia - Raleigh NC
Elena M. Gonzalez - Raleigh NC
Tina M. Lee - Raleigh NC
LiFeng Wang - Raleigh NC
Havish Koorapaty - Raleigh NC

Assignee:

North Carolina State University - Raleigh NC

International Classification:

H03M 1300

US Classification:

371 43

Abstract:

A convolutional encoding/decoding system encodes a data bit stream into n bit parity sets from k bit data bit sets, using code words of length L. The system is dependent upon the finding that unique data to parity tables can be generated where both data and parity bit blocks are w bits in length. The value of w=n(L-k)/(n-k). An encoded parity bit stream is subjected to Exclusive OR operation through a connection mask or masks that are dependent upon the encoding code words. The Exclusive OR operation generates syndrome symbols indicative of the presence of errors in the parity bit stream and which are employed to address a correction table. Parity correction values are derived from the correction table and are used to revise the parity bit stream, which is then decoded, using a parity to data table. A number of parity correction procedures are disclosed.