Phuoc Tran

US Patent:

20070067720, Mar 22, 2007

Filed:

Sep 19, 2005

Appl. No.:

11/162668

Inventors:

Phuoc Tran - San Jose CA, US

Assignee:

XMLUNIFY - San Jose CA

International Classification:

G06F 17/00

US Classification:

715532000, 715535000

Abstract:

A method of replacing a typing word with unmarked vowels with Vietnamese words containing diacritically marked characters when entering Vietnamese text in a Desktop/Notebook PC or the like. After an unmarked word is entered and displayed on a display device, the numbered list of possibly matched Vietnamese words with diacritical marks is then displayed in a pop-up window, typically immediately under/above and to the left/right of the caret or at the lower right-hand corner of the screen. The numeric keys on the keyboard/keypad can be used to choose a Vietnamese word from the list for replacing the typing unmarked word with the one chosen.

US Patent:

20140121130, May 1, 2014

Filed:

Jul 11, 2012

Appl. No.:

14/131925

Inventors:

Dean W. Felsher - San Mateo CA, US
Phuoc Tran - Ellicott City MD, US
Stacey Adam - Santa Clara CA, US
David I. Bellovin - Sunnyvale CA, US

International Classification:

C12Q 1/68

US Classification:

506 9, 506 16

Abstract:

Expression of MYC alone, in a conditional transgenic mouse model of Twist1- and MYC-induced hepatocellular carcinoma (HCC), resulted in tumors that failed to metastasize, whereas Twist1 co-expression with MYC resulted in tumors associated with extra-hepatic metastases to the lymph nodes, spleen, peritoneum, and lungs. Twist1 also caused a marked increase in circulating tumor cells. Combined inactivation of Twist1 and MYC resulted in sustained regression of both primary and metastatic tumors as shown by gross and microscopic pathology, X-ray computed tomography and bioluminescence imaging, as well as the suppression of circulating tumor cells. Through genomic analysis a 20-gene signature comprising 17 up-regulated genes and 3 down-regulated genes has been identified that is highly predictive of metastasis and overall survival in human patients with HCC. Another aspect of the disclosure methods of determining the metastatic status of an hepatocellular carcinoma of a patient, comprising obtaining a first differential gene expression profile from a carcinoma sample from a subject having an hepatocellular carcinoma and creating a report summarizing the normalized data obtained by the first gene expression analysis and including a determination of the metastatic status of the hepatic carcinoma.