Robert K Buck

US Patent:

62585487, Jul 10, 2001

Filed:

Jun 5, 1998

Appl. No.:

9/092191

Inventors:

Robert L. Buck - Sherwood OR

Assignee:

A-Fem Medical Corporation - Portland OR

International Classification:

G01N 33558

US Classification:

435 71

Abstract:

Lateral flow device and method are provided for performing semi-quantitative visual or instrument-based detection in a test sample of a large molecule analyte that contains two binding domains,. alpha. and. beta. The device contains two reagents, a contrast reagent and an indicator reagent, and an analyte test zone (ATZ) that contains a fixed number of immobilized. alpha. -domain-specific binding sites. The contrast and indicator reagents each contain signal generators such that the two reagents contrast each other in different regions of a visual, spectrophotometric, calorimetric or fluorometric spectrum. The contrast reagent is prebound to an. alpha. -region-fragment of the analyte of interest and, therefore, does not react with the analyte of interest in the test sample. The indicator reagent is attached to a binding ligand specific for the. beta. -domain of the analyte of interest.

US Patent:

63066653, Oct 23, 2001

Filed:

Oct 13, 1999

Appl. No.:

9/417957

Inventors:

Robert Lee Buck - Sherwood OR
Huiying Wang - Portland OR
Timothy Patrick Hyatt - Dundee OR
Paul Andrew Mueggler - Portland OR

Assignee:

A-Fem Medical Corporation - Portland OR

International Classification:

G01N 33544

US Classification:

436530

Abstract:

Microporous solid phase materials that are suitable for lateral flow and other assays for detecting the presence of analytes in test samples, that are stable under variations in humidity and, even after storage for extended periods of time, can form stable covalent bonds with molecules containing a free primary or secondary amine group or sulfhydryl group are described. The invention further concerns chemically derivatized solid phase materials, and conjugates comprising such materials. Examples of lateral flow devices for the quantitative or semi-quantitative determination of an analyte in a biological sample are described.

US Patent:

20140227681, Aug 14, 2014

Filed:

Apr 22, 2014

Appl. No.:

14/258995

Inventors:

William H. Fleming - Tualatin OR, US
Robert Buck - Fairview OR, US
Dan Morrow - Redwood City CA, US
Louis Dietz - Mountain View CA, US
Scott Myrick - Portland OR, US

Assignee:

QUANTRX BIOMEDICAL CORPORATION - Tualatin OR

International Classification:

G01N 21/64
G01N 33/558
G01N 33/53

US Classification:

435 5, 422 69, 436501, 435 792, 4352872, 435 74

Abstract:

Systems and methods for determining the presence and/or amount of analytes in a fluid sample are described.

Address:

613 Yesterday Dr, Lindale, TX 75771

VIN:

2A8HR54119R665512

Make:

CHRYSLER

Model:

TOWN AND COUNTRY

Year:

2009