Shaun Lee Bailey

US Patent:

20180186842, Jul 5, 2018

Filed:

Dec 29, 2017

Appl. No.:

15/859094

Inventors:

- La Jolla CA, US
Nicholas Bauman - San Diego CA, US
Randor R. Radakovits - Poway CA, US
Roberto Spreafico - San Diego CA, US
Fedor Kuzminov - San Diego CA, US
Imad Ajjawi - San Diego CA, US
Saheed Imam - San Diego CA, US
Andrew Schultz - San Diego CA, US
Kathleen Kwok - San Diego CA, US
Moena Aqui - San Diego CA, US
Jennifer Nominati - San Diego CA, US
John Verruto - San Diego CA, US
Shaun Bailey - San Diego CA, US

International Classification:

C07K 14/405
C12N 1/36
C12N 1/12
C12P 7/64
C12P 21/00
C12N 15/01
C12N 15/82

Abstract:

Disclosed herein are mutant photosynthetic microorgnaisms having an attenuated SGI1 gene. The mutants have reduced chlorophyll and increased productivity with respect to wild type cells. Also disclosed are methods of using such mutants for producing biomass or bioproducts, and methods of screening for such mutants.

US Patent:

20170114107, Apr 27, 2017

Filed:

Oct 20, 2016

Appl. No.:

15/299457

Inventors:

- La Jolla CA, US
Christen G. DiPetrillo - Santa Clara CA, US
Jay McCarren - Cardiff CA, US
Shaun Bailey - San Diego CA, US

International Classification:

C07K 14/405
C12N 15/90
C12N 15/113
C12N 1/12

Abstract:

Mutant photosynthetic algae having increased biomass productivity are provided. The mutants have attenuated expression of violaxanthin chlorophyll a binding proteins (VCP) or fucoxanthin chlorophyll a/c binding proteins (FCP), reduced chlorophyll, higher apparent ETR(II), little to no reduction in Pper cell, and decreased NPQ over a wide range of light intensities. Provided herein are constructs for attenuating or disrupting VCP or FCP genes. Also provided are methods of culturing VCP or FCP mutants for the production of biomass or other products.