Zhongping Ping Yu

US Patent:

20030091999, May 15, 2003

Filed:

Mar 29, 2001

Appl. No.:

09/821160

Inventors:

Zhongping Yu - San Diego CA, US

International Classification:

C12Q001/68
G01N033/53
C07H021/04

US Classification:

435/006000, 435/007100, 536/023100

Abstract:

The present invention provides efficient methods for identifying nucleic acid molecules and polypeptides encoded thereby. These methods can be performed using translation systems or methods. The result of these methods is a complex that binds its own encoding nucleic acid molecule. The complex preferably includes the polypeptide and nucleic acid molecule such that the nucleic acid molecule encodes at least a portion of the polypeptide.

US Patent:

20010046680, Nov 29, 2001

Filed:

May 4, 2001

Appl. No.:

09/849020

Inventors:

Zhongping Yu - San Diego CA, US

International Classification:

C12Q001/68
C07H021/02
C07H021/04

US Classification:

435/006000, 536/023100

Abstract:

The present invention provides efficient methods for identifying nucleic acid molecules and polypeptides encoded thereby. These methods can be performed using transcription and translation systems or methods, or using translation methods. The result of these methods is a peptide or polypeptide that binds its own encoding nucleic acid molecule. The invention includes nucleic acid molecules that comprise an open reading frame, and that comprise linking moieties that can link the nucleic acid molecules to the polypeptides they encode. The invention methods of identifying test compounds and targets using these nucleic acid molecules.