Feinberg school of medicine northwestern university
Sep 2016
Position:
Adjunct professor, pharmacology
Education
Degree:
Doctorates, Doctor of Philosophy
School / High School:
University of Illinois College of Medicine
Specialities:
Biochemistry, Philosophy
Skills
Drug Discovery • Lifesciences • Molecular Biology • Biotechnology • Drug Development • Oncology • Cancer • Pharmaceutical Industry • Biochemistry • Pharmacology • Clinical Research • Cell Biology • Regulatory Affairs • Drug Testing • Targeted Drug Delivery • Orphan Drugs • U.s. Food and Drug Administration • Cancer Therapeutics
The present invention relates to nanoparticle encapsulated arsenic and platinum compositions and methods of use thereof. In particular, the present invention provides co-encapsulation of active forms of arsenic and platinum drugs into liposomes, and methods of using such compositions for the diagnosis and treatment of cancer.
- Fort Worth TX, US Andrew MAZAR - Lake Forest IL, US
International Classification:
A61K 31/407 A61K 31/519
Abstract:
The present invention provides methods of treating myelofibrosis in a patient by administering to the patient a therapeutically effective amount of a 08K-3β inhibitor such as 3-(5-fluorobenzofuran-3-y1)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-y1)pynOle-2,5-dione, or a pharmaceutically acceptable salt thereof, optionally in combination with a therapeutically effective amount of a JAK inhibitor such as ruxolitinib, or a pharmaceutically acceptable salt thereof.
The present invention relates to nanoparticle encapsulated arsenic and platinum compositions and methods of use thereof. In particular, the present invention provides co-encapsulation of active forms of arsenic and platinum drugs into liposomes, and methods of using such compositions for the diagnosis and treatment of cancer.
- Evanston IL, US Haimei Chen - Evanston IL, US Andrew Mazar - Highland Park IL, US
Assignee:
NORTHWESTERN UNIVERSITY - Evanston IL
International Classification:
A61K 9/127 C07F 15/00 C07F 9/72 A61K 31/282
US Classification:
424450, 514492, 556136, 556 30, 514504
Abstract:
The present invention relates to nanoparticle encapsulated arsenic and platinum compositions and methods of use thereof. In particular, the present invention provides co-encapsulation of active forms of arsenic and platinum drugs into liposomes, and methods of using such compositions for the diagnosis and treatment of cancer.
Feinberg School of Medicine Northwestern University
Adjunct Professor, Pharmacology
Northwestern University Jun 2009 - Aug 2016
Entrepeneur-In-Residence, Research Professor
Northwestern University Apr 2009 - Aug 2016
Director, Center For Developmental Therapeutics
Monopar Therapeutics Apr 2009 - Aug 2016
Co-Founder, Director, Chief Scientific Officer and Executive Vp, R and D
Actuate Therapeutics Apr 2009 - Aug 2016
Co-Founder, Principle Scientific Advisor
Education:
University of Illinois College of Medicine
Doctorates, Doctor of Philosophy, Biochemistry, Philosophy
Skills:
Drug Discovery Lifesciences Molecular Biology Biotechnology Drug Development Oncology Cancer Pharmaceutical Industry Biochemistry Pharmacology Clinical Research Cell Biology Regulatory Affairs Drug Testing Targeted Drug Delivery Orphan Drugs U.s. Food and Drug Administration Cancer Therapeutics