Brian Meshkin

US Patent:

20060253263, Nov 9, 2006

Filed:

Apr 11, 2006

Appl. No.:

11/402173

Inventors:

Brian Meshkin - Temecula CA, US

International Classification:

G06F 19/00

US Classification:

702020000

Abstract:

The present invention provides a method of effectively measuring risk for therapeutic toxicity of a subject having an autoimmune disorder or cancer and predicting and evaluating therapeutic efficacy of immunosuppressive therapies for autoimmune diseases and cancers before or after starting therapy. The present invention also provides for determining a drug metabolite level of a subject during therapy and measuring periodically the drug metabolite level of a subject on maintenance therapy to ensure treatment compliance and continued therapeutic response by measuring minimal clinical important differences (MCID) in the drug metabolite levels. The present invention also provides for a method to effectively optimize the selection and dose of immunosuppressive therapies of a subject having an autoimmune disease or cancer to improve therapeutic efficacy and reduce therapeutic toxicity prior to starting concomitant biologic therapy and before or after the subject has failed to respond to the at least one immunosuppressive agent.

US Patent:

20060062859, Mar 23, 2006

Filed:

Aug 5, 2005

Appl. No.:

11/197980

Inventors:

Kenneth Blum - San Antonio TX, US
Brian Meshkin - Temecula CA, US
Bernard Downs - Lederach PA, US

International Classification:

A61K 36/30
A61K 38/38
A61K 31/737
A61K 31/56

US Classification:

424725000, 424765000, 424769000, 435006000, 514002000, 514054000, 514171000

Abstract:

The present invention relates to a composition and custom business model and methods to measure genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well as the metabolism, efficacy and/or toxicity associated with specific vitamins, minerals, herbal supplements, homeopathic ingredients, and other ingredients for the purposes of customizing a subject's nutritional supplements with custom formulations to optimize health outcomes.