Catherine L Mccall

US Patent:

6455686, Sep 24, 2002

Filed:

Apr 15, 1999

Appl. No.:

09/292225

Inventors:

Catherine A. McCall - Boulder CO
Shirley Wu Hunter - Fort Collins CO
Eric R. Weber - Fort Collins CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07H 2102

US Classification:

536 234, 36 231, 36 2432

Abstract:

The present invention relates to high molecular weight Dermatophagoides proteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins.

US Patent:

6573372, Jun 3, 2003

Filed:

Jan 7, 2000

Appl. No.:

09/479614

Inventors:

Catherine McCall - Boulder CO
Eric Weber - Fort Collins CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07H 2104

US Classification:

536 2353, 536 231, 536 235, 514 44

Abstract:

The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins; antibodies to the proteins; cells transformed with the nucleic acid molecules; assays employing the transformed cells, nucleic acids, antibodies and/or proteins or portions thereof; methods for treating IgE-mediated responses (ie. allergy) using the materials provided; methods for eliciting an immune response to IgE and kits containing the nucleic acid molecules, proteins or derivatives thereof (ie. antibodies).

US Patent:

6703360, Mar 9, 2004

Filed:

Apr 9, 2001

Appl. No.:

09/828995

Inventors:

Catherine A. McCall - Boulder CO
Liang Tang - Fort Collins CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07K 14705

US Classification:

514 2, 4241921, 536 235, 530350, 530351, 5303873, 435 691, 435 697, 4353201

Abstract:

The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present invention discloses nucleic acid molecules encoding canine IgG, including species-specific regions of the heavy chain of canine IgG, and canine IL-13R alpha chain (IL-13R) proteins, particularly canine interleuken receptor alpha 1 (IL-13R1) and canine interleuken receptor alpha 2 (IL-13R2) proteins. Also included are canine IgG and IL-13R proteins, antibodies having selectivity for such proteins, inhibitors of such proteins and/or nucleic acid molecules, cells transformed with said nucleic acid molecules, assays employing such cells, nucleic acids molecules, proteins, antibodies and/or inhibitors, and therapeutic compositions comprising said nucleic acids molecules, proteins, antibodies and/or inhibitors. Also included are kits containing said molecules or chimera thereof, including their use to evaluate and regulate an immune response in an animal.

US Patent:

7128921, Oct 31, 2006

Filed:

Sep 14, 2000

Appl. No.:

09/662293

Inventors:

Catherine A. McCall - Boulder CO, US
Shirley Wu Hunter - Fort Collins CO, US
Eric R. Weber - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

A61K 39/395

US Classification:

4242751, 530324, 530326, 530857, 435275

Abstract:

The present invention relates to high molecular weight proteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins.

US Patent:

7183386, Feb 27, 2007

Filed:

Apr 7, 2003

Appl. No.:

10/409772

Inventors:

Catherine McCall - Boulder CO, US
Eric Weber - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

C07K 16/00

US Classification:

5303871, 53038822, 4241331, 4241411, 4241441, 4241851, 536 2353

Abstract:

The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins; antibodies to the proteins; cells transformed with the nucleic acid molecules; assays employing the transformed cells, nucleic acids, antibodies and/or proteins or portions thereof; methods for treating IgE-mediated responses (ie. allergy) using the materials provided; methods for eliciting an immune response to IgE and kits containing the nucleic acid molecules, proteins or derivatives thereof (ie. antibodies).

US Patent:

7256263, Aug 14, 2007

Filed:

Aug 13, 2002

Appl. No.:

10/218743

Inventors:

Catherine A. McCall - Boulder CO, US
Shirley Wu Hunter - Fort Collins CO, US
Eric R. Weber - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

A61K 38/00
C07K 1/00
C07K 14/00

US Classification:

530350, 530300

Abstract:

The present invention relates to high molecular weight proteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins.

US Patent:

7378275, May 27, 2008

Filed:

Jan 7, 2004

Appl. No.:

10/753159

Inventors:

Catherine A. McCall - Boulder CO, US
Liang Tang - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

C07H 21/04
C12N 15/19
C07K 14/54
C07K 19/00

US Classification:

435325, 435 691, 435 697, 4353201, 536 235, 536 245, 530350, 5303873

Abstract:

The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present invention discloses nucleic acid molecules encoding canine IgG, including species-specific regions of the heavy chain of canine IgG, and canine IL-13R alpha chain (IL-13Rα) proteins, particularly canine interleuken receptor alpha 1 (IL-13Rα1) and canine interleuken receptor alpha 2 (IL-13Rα2) proteins. Also included are canine IgG and IL-13Rα proteins, antibodies having selectivity for such proteins, inhibitors of such proteins and/or nucleic acid molecules, cells transformed with said nucleic acid molecules, assays employing such cells, nucleic acids molecules, proteins, antibodies and/or inhibitors, and therapeutic compositions comprising said nucleic acids molecules, proteins, antibodies and/or inhibitors. Also included are kits containing said molecules or chimera thereof, including their use to evaluate and regulate an immune response in an animal.

US Patent:

7582735, Sep 1, 2009

Filed:

Feb 16, 2007

Appl. No.:

11/676048

Inventors:

Catherine McCall - Boulder CO, US
Eric Weber - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

A61K 39/395

US Classification:

5303871, 530862, 530866, 530868, 4241301, 4241331, 4241851, 424805, 424809

Abstract:

The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins; antibodies to the proteins; cells transformed with the nucleic acid molecules; assays employing the transformed cells, nucleic acids, antibodies and/or proteins or portions thereof; methods for treating IgE-mediated responses (ie. allergy) using the materials provided; methods for eliciting an immune response to IgE and kits containing the nucleic acid molecules, proteins or derivatives thereof (ie. antibodies).