- Osaka, JP Yuwei Wang - Oceanside CA, US Haiqing Yin - San Marcos CA, US Liping Wang - Carlsbad CA, US Dong Liu - Irvine CA, US Wenbin Ying - San Diego CA, US
This invention provides compositions for making a solid lyophile of one or more nucleic acid active agents, which can be reconstituted as a drug product. The composition can include an aqueous suspension of lipid nanoparticles in a pharmaceutically acceptable solution, wherein the lipid nanoparticles encapsulate one or more nucleic acid active agents, a dextrin compound, and a saccharide compound. The nucleic acid active agents can be RNAi molecules capable of mediating RNA interference, as well as other RNAs and oligonucleotides.
Compositions And Methods For Nanoparticle Lyophile Forms
- Osaka, JP Yuwei Wang - Oceanside CA, US Haiqing Ying - San Marcos CA, US Liping Wang - Carlsbad CA, US Dong Liu - Irvine CA, US Wenbin Ying - San Diego CA, US
International Classification:
A61K 9/19 C12N 15/113 A61K 9/14
Abstract:
This invention provides compositions for making a solid lyophile of one or more nucleic acid active agents, which can be reconstituted as a drug product. The composition can include an aqueous suspension of lipid nanoparticles in a pharmaceutically acceptable solution, wherein the lipid nanoparticles encapsulate one or more nucleic acid active agents, a dextrin compound, and a saccharide compound. The nucleic acid active agents can be RNAi molecules capable of mediating RNA interference, as well as other RNAs and oligonucleotides.
as Fujian Strait Textile Technology Co. are switching their business models to target the home market. It used to sell 60% of its products to Europe and the U.S. before the coronavirus crisis wiped out those sales. Now, Dong Liu, the companys vice president, is looking for opportunities at home.