Genshi L Zhao

Address:

5025 E 82 St, Indianapolis, IN 46250

VIN:

19UUA66297A043493

Make:

ACURA

Model:

TL

Year:

2007

US Patent:

H002021, May 7, 2002

Filed:

Aug 19, 1999

Appl. No.:

09/377465

Inventors:

JoAnn Hoskins - Indianapolis IN
Genshi Zhao - Indianapolis IN
Pamela Kay Rockey - Franklin IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

G01N 33554

US Classification:

435 732, 435 712

Abstract:

The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.

US Patent:

H002070, Jul 1, 2003

Filed:

Dec 8, 1997

Appl. No.:

08/987119

Inventors:

Jo Ann Hoskins - Indianapolis IN
Timothy Ivan Meier - Franklin IN
Pamela Kay Rockey - Franklin IN
Genshi Zhao - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C12N 1531

US Classification:

435 691, 4353201, 4352523, 536 237, 536 231

Abstract:

The invention provides isolated nucleic acid compounds encoding a DNA ligase of Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

US Patent:

H002085, Oct 7, 2003

Filed:

Jan 28, 1998

Appl. No.:

09/014897

Inventors:

Jo Ann Hoskins - Indianapolis IN
Genshi Zhao - Indianapolis IN
Pamela K. Rockey - Indianapolis IN
Franklin H. Norris - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C12N 1509

US Classification:

435 693, 530350

Abstract:

The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.

US Patent:

8268869, Sep 18, 2012

Filed:

May 4, 2010

Appl. No.:

12/773186

Inventors:

Daohong Chen - Westfield IN, US
Hong-Yu Li - Zionsville IN, US
Genshi Zhao - Westfield IN, US

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07D 401/14
A61K 31/4439

US Classification:

514338, 5462767

Abstract:

The present invention provides vinyl indazolyl compounds useful in the treatment of cancer.

US Patent:

20030068802, Apr 10, 2003

Filed:

Jun 29, 2001

Appl. No.:

09/897645

Inventors:

Nicholas Chirgadze - Indianapolis IN, US
Stephen Briggs - Indianapolis IN, US
Genshi Zhao - Indianapolis IN, US
Kelly McAllister - Indianapolis IN, US

International Classification:

C12N009/10
G06F019/00
G01N033/48
G01N033/50

US Classification:

435/193000, 702/019000

Abstract:

Provided are methods of purifying and crystallizing acyl carrier protein synthase (AcpS) enzyme, crystals of AcpS, the use of such crystals to determine the three-dimensional structure of AcpS enzymes, and the three-dimensional structure of AcpS. The three-dimensional crystal structure of AcpS can be used in medical diagnostics to produce antibodies that permit detection of both in vitro and in vivo. The three-dimensional crystal structure of AcpS can also be used in pharmaceutical discovery and development to identify and design compounds that inhibit the biochemical activity of AcpS enzyme in bacteria. Inhibitory compounds identified in this way can be optimized by structure/activity studies to develop antibacterial pharmaceutical compounds useful for the prevention or treatment of bacterial infections.

US Patent:

61626171, Dec 19, 2000

Filed:

Dec 8, 1997

Appl. No.:

8/987151

Inventors:

Stanley Gene Burgett - Indianapolis IN
Jo Ann Hoskins - Indianapolis IN
Stanley Richard Jaskunas - Natick MA
Robert Brown Peery - Brownsburg IN
Paul Robert Rosteck - Indianapolis IN
Genshi Zhao - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C12P 2106
C12P 2104
C12N 100
C12N 112

US Classification:

435 691

Abstract:

The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

US Patent:

60602821, May 9, 2000

Filed:

Dec 8, 1997

Appl. No.:

8/987144

Inventors:

Joseph Chiou-Chung Tang - Carmel IN
Patti Jean Treadway - Greenwood IN
Genshi Zhao - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C12P 2106

US Classification:

435 693

Abstract:

The invention provides isolated nucleic acid compounds encoding dpj of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

US Patent:

60717246, Jun 6, 2000

Filed:

Dec 8, 1997

Appl. No.:

8/986765

Inventors:

Robert Brown Peery - Brownsburg IN
Michele Louise Young Bellido - Indianapolis IN
Genshi Zhao - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C12P 2106

US Classification:

435 693

Abstract:

The invention provides isolated nucleic acid compounds encoding Era of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.