The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
- South San Francisco CA, US Helen LAM - Union City CA, US Seung-Joo LEE - San Francisco CA, US William MONTEITH - San Francisco CA, US Herve RHINN - San Francisco CA, US Arnon ROSENTHAL - Woodside CA, US
Assignee:
Alector LLC - South San Francisco CA
International Classification:
C07K 16/28 A61P 35/00 A61K 39/395 C12N 15/85
Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
- South San Francisco CA, US Tina SCHWABE - San Francisco CA, US Ilaria TASSI - San Francisco CA, US Helen LAM - Union City CA, US Arnon ROSENTHAL - Woodside CA, US
Assignee:
Alector LLC - South San Francisco CA
International Classification:
C07K 16/28
Abstract:
The invention is generally directed to methods and compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 and/or human TREM2. The methods provided herein find use in preventing, reducing risk, or treating an individual having dementia, frontotemporal dementia, Alzheimer's disease, Nasu-Hakola disease, or multiple sclerosis.
Anti-Siglec-5 Antibodies And Methods Of Use Thereof
- South San Francisco CA, US Rashmi BANKOTI - San Mateo CA, US Helen LAM - Union City CA, US Arnon ROSENTHAL - Woodside CA, US
Assignee:
Alector LLC - South San Francisco CA
International Classification:
C07K 16/28 A61K 47/68 A61P 35/00
Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a Siglec-5 protein, e.g., human Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
- South San Francisco CA, US Helen LAM - Union City CA, US Leonard G. PRESTA - Palo Alto CA, US Arnon ROSENTHAL - Woodside CA, US
Assignee:
Alector LLC - South San Francisco CA
International Classification:
C07K 16/28
Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a CD33 polypeptide, e.g., a mammalian CD33 or human CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
Anti-Siglec-7 Antibodies And Methods Of Use Thereof
- South San Francisco CA, US Seung-Joo LEE - Benicia CA, US Helen LAM - Union City CA, US Arnon ROSENTHAL - Woodside CA, US
Assignee:
Alector LLC - South San Francisco CA
International Classification:
C07K 16/28
Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Siglec-7 protein, e.g., human Siglec-7 or a mammalian Siglec-7, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
- South San Francisco CA, US Helen LAM - Union City CA, US Arnon ROSENTHAL - Woodside CA, US Seung-Joo LEE - Benicia CA, US Nels P. NIELSON - Hopkinton NH, US Robert PEJCHAL - Norwich VT, US
Assignee:
ALECTOR LLC - South San Francisco CA
International Classification:
C07K 16/28 C07K 16/46
Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
Anti-Siglec-5 Antibodies And Methods Of Use Thereof
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
Cloth & Dagger San Francisco, CA 2012 to 2013 Co-FounderMSA (Mine Safety Appliances) Pittsburgh, PA May 2011 to Aug 2011 InternPlant Construction Company San Francisco, CA Dec 2006 to Jul 2010 Project Manager
Education:
Carnegie Mellon University Pittsburgh, PA 2010 to 2011 MS in Product DevelopmentUniversity of California, Berkeley Berkeley, CA 2003 to 2007 BS in Civil Engineering
Skills:
SolidWorks, AutoCAD, MATLAB, Adobe Creative Suite, Rapid prototyping, Machine Shop, User Research
Jun 2014 to 2000 Director Customer Success for sales motivation SaaS start-upBrightEdge Technologies, Inc San Mateo, CA Dec 2011 to Jun 2014 Director Client Services for corporate accountsVeracode, Inc Silicon Valley, CA Dec 2010 to Dec 2011 Sr. Customer Success ManagerPromatch Silicon Valley, CA 2010 to 2010 Volunteer as workshop Facilitator and Marketing Co-LeadYAHOO!, INC Los Angeles, CA 2008 to 2009 Senior Manager, Yahoo! Network Quality for Ad ExchangeINFOSYS TECHNOLOGY CONSULTING, INC Los Angeles, CA 2004 to 2008 Senior ConsultantA LA MODE FURNISHINGS, INC Los Angeles, CA 2000 to 2002 COOPWC CONSULTING, LLP New York, NY 1997 to 2000 Management Consultant - Marketing Strategy and Operation
Education:
Cornell University Ithaca, NY 2004 MBAWellesley College Wellesley, MA 1997 BA
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Helen Lam
Lived:
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Carnegie Mellon University, UC Berkeley
About:
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I am awesome.
Helen Lam
Education:
University of California, Los Angeles - Medicine, University of California Davis - Exercise Biology
Helen Lam
Education:
University of California, Berkeley - Statistics
Helen Lam
Education:
Medford high school
Helen Lam
Education:
University of California, Merced
Helen Lam
Education:
University of California, Irvine - Criminology Law & Society and Psychology & Social Behavior
Helen Lam
Helen Lam
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