A device for delivering gas is disclosed. The device may include a chamber and a guide. The chamber may include a set of input openings for receiving the gas and an output opening for providing the gas. The set of input openings may include a first hole and a second hole. The chamber may receive a first portion of the gas through the first hole and a second portion of the gas through the second hole. The guide may include a guiding unit. The guiding unit may be disposed inside the chamber. The guiding unit may contact the first portion of the gas before the first portion of the gas contacts the second portion of the gas and may contact the second portion of the gas before the second portion of the gas contacts the first portion of the gas.
Connection Mechanisms Including Rotatably Coupled Members
A joint connector including a first member and a second member, the second member being rotatably coupled with the first member. The first member may include a first-member top surface, a first-member bottom surface, and a first passageway structure disposed between the first-member top surface and the first-member bottom surface. The second member may include a second-member top surface, a second-member bottom surface, and a second passageway structure connected to the first passageway structure and disposed between the second-member top surface and the second-member bottom surface. Whenever the first passageway structure is parallel to the second passageway structure, the first-member top surface and the second-member top surface share a first imaginary tangent plane, and the first-member bottom surface and the second-member bottom surface share a second imaginary tangent plane.
A joint connector including a first member which includes a first passageway structure and a first groove structure. The joint connector may also include a second member coupled with the first member, wherein the second member includes a second passageway structure and second groove structure, and wherein the second passageway structure may be connected to the first passageway structure. The joint connector may also include a coupling component coupling the first member with the second member. A first portion of the coupling component may be disposed inside the first groove structure. A second portion of the coupling component may be disposed inside the second groove structure. The first portion of the coupling component may at least partially surround the second portion of the coupling component.
Population Pk/Pd Linking Parameter Analysis Using Deep Learning
- South San Francisco CA, US James Lu - San Francisco CA, US
International Classification:
G16C 20/70 G16C 20/50
Abstract:
A method and system for predicting a set of linking parameters that relate pharmacokinetic and pharmacodynamic effects. One or more processors receive a population dataset that comprises a population pharmacokinetic (PK) dataset and a population pharmacodynamic (PD) dataset. The one or more processors transform the population dataset into a plurality of data density images that includes a PK data density image and a PD data density image. The one or more processors predict the set of linking parameters using the plurality of data density images.
James Lu - Redwood City CA, US Jim Chou - San Francisco CA, US William Lee - Mountain View CA, US Chris Williams - San Francisco CA, US James Warren - Redwood City CA, US Ruomu Jiang - Menlo Park CA, US
International Classification:
G16B 30/10 C12Q 1/686 G16B 50/00 G16B 40/00
Abstract:
Systems, platforms, methods and media for providing genomic services axe disclosed. In one example, a system for providing genomic services comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, store the sequence reads in a FASTQ storage file, and communicate the FASTQ file electronically to a recipient. The system also includes a genomic services platform which includes a network interface through which the sequence reads are received, and a bioinformatics processing pipeline. The bioinformatics processing pipeline includes a read alignment module configured to generate observed sequence data, and a variant calling module is operative to identify observed variants in the observed sequence data. A variant storage module is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of refined variants in response to a query.
James Lu - Redwood City CA, US Jim Chou - San Francisco CA, US William Lee - Mountain View CA, US Chris Williams - San Francisco CA, US James Warren - Redwood City CA, US Ruomu Jiang - Menlo Park CA, US
Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample are received. The platform also includes a bioinformatics processing pipeline that comprises a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the biological sample. A variant imputation module produces a set of imputed variants associated with the user and a variant storage module, operating on a server-less framework, is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants m response to the query.
James Lu - Redwood City CA, US Jim Chou - San Francisco CA, US William Lee - Mountain View CA, US Chris Williams - San Francisco CA, US James Warren - Redwood City CA, US Ruomu Jiang - Menlo Park CA, US
Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants in response to the query.
James Lu - Redwood City CA, US Jim Chou - San Francisco CA, US William Lee - Mountain View CA, US Chris Williams - San Francisco CA, US James Warren - Redwood City CA, US Ruomu Jiang - Menlo Park CA, US
Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample obtained from a user are received. The platform also includes a bioinformatics processing pipeline that includes a read alignment module configured to receive a genomics file from genomic sequencing equipment and use data contained therein to generate observed sequence data by aligning the sequence reads relative to a reference sequence. A variant calling module identifies observed variants in the observed sequence data and stores the observed variants in a variant calling file. A variant refinement module produces genotype data including a set of refined variants associated with the user, and a variant imputation module produces a set of imputed variants associated with the user. The variant imputation module can separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.
Dr. Lu graduated from the Washington University School of Medicine in 1996. He works in Bridgeton, MO and specializes in Surgery , Neurological. Dr. Lu is affiliated with Sisters Of Saint Mary Saint Clare Health Center and SSM DePaul Health Center.
Dr. Lu graduated from the New York University School of Medicine in 1977. He works in Shreveport, LA and 1 other location and specializes in Infectious Disease and Internal Medicine. Dr. Lu is affiliated with University Health Center.
James Lu (1988-1992), Cathy Kramlich (1978-1984), Geneva Zuccolo (1996-2000), Kristen Davis (1989-1993), Ashley McMahon (2003-2007), Damon McClurg (1977-1986)