Jing H Liu

US Patent:

20100323393, Dec 23, 2010

Filed:

Jun 22, 2010

Appl. No.:

12/820933

Inventors:

Xiuli An - Bayside NY, US
Mohandas Narla - New York NY, US
Jing Liu - Woodside NY, US
Susanne Heck - Bronx NY, US

International Classification:

C12Q 1/06
C12N 5/078
C12Q 1/02
C12Q 1/04

US Classification:

435 39, 435325, 435 29, 435 34

Abstract:

Disclosed herein are methods for the isolation, identification, and quantification of red blood cells and red blood cell precursors at different developmental stages. Also disclosed are methods for monitoring ex vivo proliferation and differentiation of red blood cells and red blood cell progenitors.

US Patent:

20120295285, Nov 22, 2012

Filed:

Jul 13, 2012

Appl. No.:

13/548761

Inventors:

Xiuli An - Bayside NY, US
Mohandas Narla - New York NY, US
Jing Liu - Woodside NY, US
Susanne Heck - Bronx NY, US

Assignee:

NEW YORK BLOOD CENTER, INC. - New York NY

International Classification:

C12Q 1/04
G01N 21/64
G01N 33/566
C12Q 1/06

US Classification:

435 725, 435 34, 435 39

Abstract:

Disclosed herein are methods for the isolation, identification, and quantification of red blood cells and red blood cell precursors at different developmental stages. Also disclosed are methods for monitoring ex vivo proliferation and differentiation of red blood cells and red blood cell progenitors.

US Patent:

20130017250, Jan 17, 2013

Filed:

Jul 16, 2012

Appl. No.:

13/550567

Inventors:

Henry Ginsberg - Dobbs Ferry NY, US
Jing Liu - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York City NY

International Classification:

A61K 38/44
G01N 21/76
A61P 3/10
C07H 21/04
A61K 9/127
A61P 9/00
G01N 21/17
G01N 21/64

US Classification:

424450, 435 29, 435 8, 424 944, 536 241

Abstract:

It was discovered that insulin binding to insulin receptors signals the upregulation of expression of the liver enzyme deiodinase 1 (Dio1), which in turn activates the ApoA-1 promoter, thereby thereby increasing ApoA-1 expression (primarily in the liver), that in turn raises the levels of plasma ApoA-1, the major and necessary protein in HDLC. Certain embodiments of the invention are directed to methods for increasing circulating HDLC levels in an animal by administering therapeutically effective amounts of Dio1, or by increasing the level of Dio1 through gene therapy.

US Patent:

20130059836, Mar 7, 2013

Filed:

May 12, 2011

Appl. No.:

13/641729

Inventors:

Xiaodong Wang - Chapel Hill NC, US
Jing Liu - Carrboro NC, US
Chao Yang - Franklin Park NJ, US
Weihe Zhaug - Chapel Hill NC, US
Stephen Frye - Chapel Hill NC, US
Dmitri Kireev - Chapel Hill NC, US

International Classification:

C07D 487/04
A61P 35/02
A61K 31/551
A61P 35/00
A61K 31/519
A61K 31/5377

US Classification:

51421021, 5142621, 544262, 51425216, 5142345, 544122, 514218, 540575

Abstract:

Compound of Formula (I): are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof in the treatment of cancer.

US Patent:

20210261538, Aug 26, 2021

Filed:

Feb 22, 2019

Appl. No.:

16/970305

Inventors:

- New YOrk NY, US
Jing Liu - Oradell NJ, US
Yudao Shen - New York NY, US
Ernesto Guccione - New York NY, US
Martin Walsh - New York NY, US
Almudena Bosch - New York NY, US
Megan Schwarz - New York NY, US

International Classification:

C07D 417/14
C07D 401/14

Abstract:

Disclosed are protein arginine methyltransferase 5 (PRMT5) degradation/disruption compounds including a PRMT5 ligand, a degradation/disruption tag and a linker, and methods for use of such compounds in the treatment of PRMT5-mediated diseases. The PRMT5 degraders disclosed herein offer a novel mechanism for treating PRMT5-mediated diseases compared to small molecule inhibitors of PRMT5 activity.

US Patent:

20210016295, Jan 21, 2021

Filed:

Jul 20, 2020

Appl. No.:

16/933615

Inventors:

Robert Bret Carr - Durham NC, US
Jing Liu - Somerville MA, US

International Classification:

B04B 1/06
B04B 1/16
B04B 9/12
B04B 11/05
B04B 5/04

Abstract:

A centrifugal separator includes disposable cartridge having a cylindrical bowl, a core tube assembly, and an annular piston disposed around the core tube assembly and inside the inner surface of the bowl. The disposable cartridge may be automatically loaded and withdrawn from the separator. Feed liquid is injected down the core tube assembly into the lower portion of the bowl, raising the annular piston, while the bowl rotates at high speed, separating solids from the feed liquid to accumulate along the inner surface of the bowl, while collecting clarified centrate as it exits the top of the bowl and through the core tube assembly. In a solids discharge mode, the annular piston is urged downward along a vertical axis to force accumulated solids from the bowl.

US Patent:

20170121804, May 4, 2017

Filed:

Sep 18, 2014

Appl. No.:

15/317792

Inventors:

- Westbury NY, US
Jing LIU - Syosset NY, US
Montia NESTLER - Ridgefield NJ, US
Eugene STELMACK - Fort Saskatchewan, CA
Mathias RUNTE - Bonn, DE

Assignee:

OERLIKON METCO (US) INC. - Westbury NY

International Classification:

C23C 4/04
C09D 129/04
C09D 1/00
C09D 7/12
B22F 1/00
C23C 4/134

Abstract:

A powder composition adapted for use in suspension thermal spray coating processes. The powder includes agglomerated and/or non-agglomerated particles having at least one dispersing agent deposited thereon. The composition results in a homogeneous, stable suspension when combined with a liquid carrier for use in suspension thermal spray coating processes.

US Patent:

20150284392, Oct 8, 2015

Filed:

Oct 16, 2013

Appl. No.:

14/436356

Inventors:

- Chapel Hill NC, US
Jing Liu - Carrboro NC, US
Chao Yang - Chapel Hill NC, US
Weihe Zhang - Chapel Hill NC, US
Stephen Frye - Chapel Hill NC, US
Dmitri Kireev - Chapel Hill NC, US

International Classification:

C07D 487/04

Abstract:

Compounds of Formula I are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof.

Address:

100 Hedspeth Ln, Cary, NC 27519

Phone:

9194608801

VIN:

JTHBJ46G072083735

Make:

LEXUS

Model:

ES 350

Year:

2007