Jing F Liu

US Patent:

20100323393, Dec 23, 2010

Filed:

Jun 22, 2010

Appl. No.:

12/820933

Inventors:

Xiuli An - Bayside NY, US
Mohandas Narla - New York NY, US
Jing Liu - Woodside NY, US
Susanne Heck - Bronx NY, US

International Classification:

C12Q 1/06
C12N 5/078
C12Q 1/02
C12Q 1/04

US Classification:

435 39, 435325, 435 29, 435 34

Abstract:

Disclosed herein are methods for the isolation, identification, and quantification of red blood cells and red blood cell precursors at different developmental stages. Also disclosed are methods for monitoring ex vivo proliferation and differentiation of red blood cells and red blood cell progenitors.

US Patent:

20120295285, Nov 22, 2012

Filed:

Jul 13, 2012

Appl. No.:

13/548761

Inventors:

Xiuli An - Bayside NY, US
Mohandas Narla - New York NY, US
Jing Liu - Woodside NY, US
Susanne Heck - Bronx NY, US

Assignee:

NEW YORK BLOOD CENTER, INC. - New York NY

International Classification:

C12Q 1/04
G01N 21/64
G01N 33/566
C12Q 1/06

US Classification:

435 725, 435 34, 435 39

Abstract:

Disclosed herein are methods for the isolation, identification, and quantification of red blood cells and red blood cell precursors at different developmental stages. Also disclosed are methods for monitoring ex vivo proliferation and differentiation of red blood cells and red blood cell progenitors.

US Patent:

20130017250, Jan 17, 2013

Filed:

Jul 16, 2012

Appl. No.:

13/550567

Inventors:

Henry Ginsberg - Dobbs Ferry NY, US
Jing Liu - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York City NY

International Classification:

A61K 38/44
G01N 21/76
A61P 3/10
C07H 21/04
A61K 9/127
A61P 9/00
G01N 21/17
G01N 21/64

US Classification:

424450, 435 29, 435 8, 424 944, 536 241

Abstract:

It was discovered that insulin binding to insulin receptors signals the upregulation of expression of the liver enzyme deiodinase 1 (Dio1), which in turn activates the ApoA-1 promoter, thereby thereby increasing ApoA-1 expression (primarily in the liver), that in turn raises the levels of plasma ApoA-1, the major and necessary protein in HDLC. Certain embodiments of the invention are directed to methods for increasing circulating HDLC levels in an animal by administering therapeutically effective amounts of Dio1, or by increasing the level of Dio1 through gene therapy.

US Patent:

20130158258, Jun 20, 2013

Filed:

Feb 12, 2013

Appl. No.:

13/765639

Inventors:

Janssen Pharmaceutica NV - New Brunswick NJ, US
Frank CHAVEZ - San Diego CA, US
James P. EDWARDS - San Diego CA, US
Annie E. FITZGERALD - San Diego CA, US
Jing LIU - San Diego CA, US
Neelakandha S. MANI - San Diego CA, US
Michele C. RIZZOLIO - San Diego CA, US
Brad M. SAVALL - San Diego CA, US
Deborah M. SMITH - San Diego CA, US
Jennifer D. VENABLE - Solana Beach CA, US
Jianmei WEI - San Diego CA, US
Danielle K. WIENER - La Jolla CA, US
Ronald L. WOLIN - San Diego CA, US

Assignee:

Janssen Pharmaceutica NV - New Brunswick NJ

International Classification:

C07D 239/48
C07D 471/04
C07D 405/14
C07D 409/14
C07D 487/10
C07D 403/04

US Classification:

540575, 544230, 544295, 544323

Abstract:

2-Aminopyrimidine compounds are described, which are useful as Hreceptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by Hreceptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.

US Patent:

20130158259, Jun 20, 2013

Filed:

Feb 13, 2013

Appl. No.:

13/766375

Inventors:

JANSSEN PHARMACEUTICA NV - New Brunswick NJ, US
Frank CHAVEZ - San Diego CA, US
James P. EDWARDS - San Diego CA, US
Annie E. FITZGERALD - San Diego CA, US
Jing LIU - San Diego CA, US
NEELAKANDHA S. MANI - San Diego CA, US
Michele C. RIZZOLIO - San Diego CA, US
Brad M. SAVALL - San Diego CA, US
Deborah M. SMITH - San Diego CA, US
Jennifer D. VENABLE - Solana Beach CA, US
Jianmei WEI - San Diego CA, US
Danielle K. WIENER - La Jolla CA, US
Ronald L. WOLIN - San Diego CA, US

Assignee:

JANSSEN PHARMACEUTICA NV - New Brunswick NJ

International Classification:

C07D 498/04
C07D 401/04
C07D 403/04
C07D 487/04
C07D 487/10
C07D 487/08
C07D 405/04
C07D 405/14
C07D 239/95
C07D 239/70
C07D 239/48
C07D 471/04

US Classification:

540575, 544295, 544323, 544253, 544230, 544105

Abstract:

2-Aminopyrimidine compounds are described, which are useful as Hreceptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by Hreceptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.

US Patent:

20180104247, Apr 19, 2018

Filed:

Oct 23, 2017

Appl. No.:

15/790700

Inventors:

- Chapel Hill NC, US
Jing Liu - Jersey City NJ, US
Weihe Zhang - Vestavia AL, US
Stephen Frye - Chapel Hill NC, US
Dmitri Kireev - Chapel Hill NC, US

International Classification:

A61K 31/519
C07D 487/18
A61K 31/5377
C07D 487/04

Abstract:

Compounds of Formula I:wherein: one of X and X′ is N and the other of X and X′ is C, are described, along with compositions containing the same and methods of use thereof in the treatment of cancer.

US Patent:

20170121804, May 4, 2017

Filed:

Sep 18, 2014

Appl. No.:

15/317792

Inventors:

- Westbury NY, US
Jing LIU - Syosset NY, US
Montia NESTLER - Ridgefield NJ, US
Eugene STELMACK - Fort Saskatchewan, CA
Mathias RUNTE - Bonn, DE

Assignee:

OERLIKON METCO (US) INC. - Westbury NY

International Classification:

C23C 4/04
C09D 129/04
C09D 1/00
C09D 7/12
B22F 1/00
C23C 4/134

Abstract:

A powder composition adapted for use in suspension thermal spray coating processes. The powder includes agglomerated and/or non-agglomerated particles having at least one dispersing agent deposited thereon. The composition results in a homogeneous, stable suspension when combined with a liquid carrier for use in suspension thermal spray coating processes.

US Patent:

20160279132, Sep 29, 2016

Filed:

Feb 29, 2016

Appl. No.:

15/055756

Inventors:

- Chapel Hill NC, US
Jing Liu - Jersey City NJ, US
Chao Yang - Franklin Park NJ, US
Weihe Zhang - Vestavia AL, US
Stephen Frye - Chapel Hill NC, US
Dmitri Kireev - Chapel Hill NC, US

International Classification:

A61K 31/519
A61K 31/551
A61K 31/5377

Abstract:

Compound of Formula I:are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof in the treatment of cancer.