John Chunkai Chiu

US Patent:

7811514, Oct 12, 2010

Filed:

Jun 14, 2007

Appl. No.:

11/762780

Inventors:

John Chiu - Torrance CA, US

International Classification:

G01N 21/00

US Classification:

422 57

Abstract:

A lateral flow chromatography test device is disclosed that includes a stopping mechanism which enables a user of the test device to stop reactions of a test by pushing the stopping mechanism downward to remove materials flowing along a test strip in the test device at a time instructed by the manufacturer or decided by the user. This stopping mechanism is adapted to freeze the test result at the stopping time so as to keep the test result as a permanent record. The invention enables qualitative tests to become quantitative or semi-quantitative tests.

US Patent:

20080311680, Dec 18, 2008

Filed:

Jun 14, 2007

Appl. No.:

11/762781

Inventors:

John Chiu - Torrance CA, US

International Classification:

G01N 33/536
C12M 1/00

US Classification:

436536, 422188

Abstract:

A method for detecting high antigen concentration is disclosed. The method enables the mobile-phase antibody, in the presence of excessive amount of antigen, to form the antibody-antigen-antibody sandwich with the immobilized solid-phase antibody effectively in a rapid lateral flow chromatographic immunoassay. The mobile-phase and/or immobilized solid-phase antibody are treated with soluble coatings to generate a delaying mechanism, so that antigen-antibody binding occurs only when both phases of antibodies and antigen are in very close proximity. A user friendly immunoassay device with a sample over-flow mechanism also facilitates such antigen-antibody binding.