- Roseville MN, US COURTNEY R. JONES - Fridley MN, US BETH ANNE-SZKUDLAREK BROWN - Plymouth MN, US JOSHUA ERICKSON - Champlin MN, US MESSAC CHE NEBA - Little Canada MN, US
Microbiota restoration therapy (MRT) compositions (e.g., oral MRT compositions) and methods for manufacturing MRT compositions are disclosed. An example method for manufacturing an MRT composition may include collecting a stool sample, purifying the stool sample to form a purified sample, stabilizing the purified sample to form a stabilized sample, converting the stabilized sample to a solid, adding one or more additives and/or excipients to the solid to form a treatment composition, and encapsulating the treatment composition.
Microbiota Restoration Therapy (Mrt) Compositions And Methods Of Manufacture
- Roseville MN, US COURTNEY R. JONES - Fridley MN, US BETH ANNE-SZKUDLAREK BROWN - Plymouth MN, US JOSHUA ERICKSON - Champlin MN, US
Assignee:
REBIOTIX, INC. - Roseville MN
International Classification:
A61K 35/74 A61K 9/48 A61K 9/19
Abstract:
Microbiota restoration therapy (MRT) compositions (e.g., oral MRT compositions) and methods for manufacturing MRT compositions are disclosed. An example method for manufacturing an MRT composition may include collecting a stool sample, purifying the stool sample to form a purified sample, stabilizing the purified sample to form a stabilized sample, converting the stabilized sample to a solid, adding one or more additives and/or excipients to the solid to form a treatment composition, and encapsulating the treatment composition.
- St. Paul MN, US Francois Ahimou - Woodbury MN, US Naiyong Jing - St. Paul MN, US Tonya D. Bonilla - Woodbury MN, US Joshua D. Erickson - Champlin MN, US Hsi-Chou Liu - Woodbury MN, US
International Classification:
C12Q 1/04
Abstract:
A composition, including: amine-modified silica nanoparticles, an indicator compound, and a liquid medium comprising water and no greater than 30 wt-% organic solvent, if present, based on the total weight of liquid medium. A method, including: providing the composition of current application; and contacting a plurality of cells or enzymes with the composition.
- St. Paul MN, US Francois Ahimou - Woodbury MN, US Naiyong Jing - St. Paul MN, US Tonya D. Bonilla - Woodbury MN, US Joshua D. Erickson - Champlin MN, US Hsi-Chou Liu - Woodbury MN, US Andrew W. Vail - Woodbury MN, US
International Classification:
C12Q 1/22 C12Q 1/34
Abstract:
A method is provided. The method includes providing an article, the article including a nonwoven substrate having a copolymer grafted thereto, the copolymer including interpolymerized monomer units of a quaternary ammonium-containing ligand monomers; an amide monomer; an oxy monomer; and a coating on the nonwoven substrate, the coating including a plurality of test microorganisms, an enzyme or a second substrate; and contacting the article with a detection medium for a period of time.
Plasma Sterilization And Drying System And Methods
- St. Paul MN, US Caleb T. Nelson - Woodbury MN, US Jodi L. Connell - St. Paul MN, US Joshua D. Erickson - Champlin MN, US Jeffrey D. Smith - Marine on St. Croix MN, US Jay R. Goetz - Deephaven MN, US Nicholas R. Powley - St. Paul MN, US Matthew T. Scholz - Woodbury MN, US
International Classification:
A61L 2/14 A61L 2/26 H01J 37/32
Abstract:
A system and methods for sterilizing and drying contaminated articles, particularly medical articles, and more particularly the hollow internal areas of medical instruments or lumens of medical endoscopes. The system includes a plasma generator having an electrode, a shield, and a dielectric gap between the electrode and the shield. A source of electrical power connected to the plasma generator applies an electrode energy density between the electrode and the shield. A source of a sterilizing gas precursor provides a flow of the sterilizing gas precursor through the plasma generator to generate a plasma, thereby forming a sterilizing gas including acidic and/or oxidizing species. The contaminated article is exposed to the sterilizing gas for a time sufficient to achieve a desired degree of sterilization. A turbulent flow of a drying gas is used to dry the contaminated article alternately with the exposure of the contaminated article to the sterilizing gas.
Microbiota Restoration Therapy (Mrt), Compositions And Methods Of Manufacture
Microbiota restoration therapy compositions and methods for manufacturing, processing, and/or delivering microbiota restoration therapy compositions are disclosed. An example method for manufacturing a microbiota restoration therapy composition may include collecting a human fecal sample and adding a diluent to the human fecal sample to form a diluted sample. The diluent may include a cryoprotectant. The method may also include mixing the diluted sample with a mixing apparatus and filtering the diluted sample. Filtering may form a filtrate. The method may also include transferring the filtrate to a sample bag and sealing the sample bag.
Microbiota Restoration Therapy (Mrt) Compositions And Methods Of Manufacture
- Roseville MN, US COURTNEY R. JONES - Fridley MN, US BETH ANNE-SZKUDLAREK BROWN - Plymouth MN, US JOSHUA ERICKSON - Champlin MN, US MESSAC CHE NEBA - Little Canada MN, US
Microbiota restoration therapy (MRT) compositions (e.g., oral MRT compositions) and methods for manufacturing MRT compositions are disclosed. An example method for manufacturing an MRT composition may include collecting a stool sample, purifying the stool sample to form a purified sample, stabilizing the purified sample to form a stabilized sample, converting the stabilized sample to a solid, adding one or more additives and/or excipients to the solid to form a treatment composition, and encapsulating the treatment composition.
Microbiota Restoration Therapy (Mrt) Compositions And Methods Of Manufacture
Microbiota restoration therapy (MRT) compositions (e.g., oral MRT compositions) and methods for manufacturing MRT compositions are disclosed. An example method for manufacturing an MRT composition may include collecting a stool sample, purifying the stool sample to form a purified sample, stabilizing the purified sample to form a stabilized sample, converting the stabilized sample to a solid, adding one or more additives and/or excipients to the solid to form a treatment composition, and encapsulating the treatment composition.