Joshua R Park

US Patent:

6915117, Jul 5, 2005

Filed:

May 3, 2001

Appl. No.:

09/850629

Inventors:

Paul P. Chominski - San Diego CA, US
Jonathan L. Kennedy - Auburn CA, US
Lawrence E. Larson - Del Mar CA, US
Joshua C. Park - Medford MA, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

H04B001/26

US Classification:

455118, 455112, 455113, 455260, 455 20

Abstract:

In a multiple stage transmitter, and analog signal is modulated and mixed to produce a radio frequency output. A separate mixing frequency signal is provided to each stage. A single frequency synthesizer is used rather than a plurality of frequency synthesizers. In a two-stage system, first and second dividers each receive the output of the frequency synthesizer and deliver a mixing signal to the first and second stages respectively. The modulus of each divider may be selected to minimize spurious signals.

US Patent:

20190300620, Oct 3, 2019

Filed:

Nov 10, 2017

Appl. No.:

16/349258

Inventors:

- La Jolla CA, US
Joshua PARK - La Jolla CA, US

International Classification:

C07K 16/28
C12N 5/0783
A61K 35/17
C07K 14/705
A61P 35/00
A61K 38/20
A61K 38/19
A61K 38/21
A61K 45/06
A61K 38/17
A61K 39/395
A61K 31/675
A61K 31/7076
A61K 9/00
C07K 14/725

Abstract:

Engineered effector cells, such as chimeric antigen receptors (CARs), are used for enhanced immunogenic response to specific antigen, such as CD46. Disclosed herein are compositions and methods of treatment a cancer overexpressing CD46, which comprises a pharmaceutical composition comprising an engineered effector cell.