Jun Liu

US Patent:

8037656, Oct 18, 2011

Filed:

Aug 8, 2008

Appl. No.:

12/188731

Inventors:

David C. Liu - Marietta GA, US
Jun Liu - Marietta GA, US

International Classification:

E04B 2/08

US Classification:

525891, 525902, 525911, 525914, 525921

Abstract:

A hardwood floor system with press down locking mechanism. Each floor board is equipped with both male and female locking mechanisms. The male locking mechanism of a floor board can be locked into the female locking mechanism of an adjacent floor board by simply exerting downward force on the floor board. The female locking mechanism is equipped with a spring slot that enables easy engagement of male and female locking mechanisms. The invention may be applied not only floor boards, but also to wall tiles and roof tiles.

US Patent:

8590799, Nov 26, 2013

Filed:

May 1, 2011

Appl. No.:

13/098475

Inventors:

Jun Liu - Vienna VA, US

International Classification:

G06K 19/06

US Classification:

235494

Abstract:

Systems, methods and apparatus of a secure RFID record are described herein. In one aspect, an apparatus of a RFID wristband comprises three layers: the top layer is a wristband, the middle layer is one RFID tag comprising one RFID chip and one tag antenna covering the wide area of the wristband, the bottom layer is made by anti-irritation materials. In another aspect, an apparatus of a RFID wristband comprises three layers: the top layer is a wristband, the middle layer has two RFID tags, each of which comprises one RFID chip and one tag antenna; the bottom layer is made by anti-irritation materials. In another aspect, a RFID system for secure communication comprises: a tag with at least two memory areas for storing an unique identifier and encoded data, respectively; a reader with at least three functions: key search, decoding process and encoding process; the unique identifier is associated with a key while the key is stored on the reader or a server connected to the reader.

US Patent:

20030125243, Jul 3, 2003

Filed:

Jul 19, 2001

Appl. No.:

09/909269

Inventors:

Jun Liu - Clarksville MD, US
Xuedong Dai - San Jose CA, US
Zhuang Su - Cambridge MA, US

International Classification:

A61K038/12
C07K007/64
C07K005/12

US Classification:

514/009000, 530/317000

Abstract:

The cyclic pentapeptide cyclo(-Arg-Gly-Asp-D-Phe-Lys-) is a highly potent and selective inhibitor for the integrin. A related compound, cyclo(-Arg-Gly-Asp-D-Phe-Val-), is a promising anticancer drug candidate; it has been found to inhibit angiogenesis and induce apoptosis in vascular cells. We have developed a synthesis of arginine containing cyclic peptides using the cyclizcation reagent 1-propanephosphonic acid cyclic anhydride (T3P) and the guanidine protecting group, 2,2,5,7,8-pentamethylchroman-6-sulfonyl (Pbf). This improved synthesis is environmentally friendly and is generally applicable to the synthesis of other cyclic peptides.

US Patent:

20080193499, Aug 14, 2008

Filed:

Jun 27, 2005

Appl. No.:

11/630596

Inventors:

Jun Liu - Clarksville MD, US
Curtis Chong - Baltimore MD, US
David J. Sullivan - Baltimore MD, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

International Classification:

A61F 2/00
A61K 31/513
A61K 31/343
A61K 31/58
A61K 31/4196
A61K 31/506
A61K 9/00
A61K 38/50
A61K 31/496

US Classification:

424423, 514274, 514470, 514176, 424 946, 51425407, 424484, 514383, 514256

Abstract:

Described herein are methods of inhibiting angiogenesis, and treating or preventing a disease or disorder (or symptoms thereof) associated with angiogenesis, wherein an anti-angiogenesis compound is administered to a subject.

US Patent:

20100330148, Dec 30, 2010

Filed:

Mar 20, 2007

Appl. No.:

12/225391

Inventors:

Jun O. Liu - Clarksville MD, US
Curtis Robert Chong - Honolulu HI, US
David J. Sullivan - Baltimore MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

A61M 31/00
A61K 38/50
A61K 31/7052
A61K 31/4174
A61K 31/496
A61K 31/4196
A61K 31/506
A61K 31/7072
A61K 31/58
A61P 35/00
A61P 17/00
A61P 7/10
A61P 19/02
A61P 29/00
A61P 3/00

US Classification:

424427, 424 946, 514 43, 514396, 514399, 51425407, 514383, 514256, 514 50, 514176

Abstract:

Described herein are methods of inhibiting IMPDH type 1, and treating or preventing a disease or disorder (or symptoms thereof) associated with IMPDH type 1, wherein an IMPDH type 1 inhibitor compound is administered to a subject.

US Patent:

20100330156, Dec 30, 2010

Filed:

Mar 22, 2010

Appl. No.:

12/729083

Inventors:

Jun O. LIU - Clarksville MD, US
Yunzhao REN - Timonium MD, US
Fan PAN - Baltimore MD, US
Curtis R. CHONG - Honolulu HI, US
Reinhold PENNER - Honolulu HI, US
Jonathan R. BEHR - Cambridge MA, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

International Classification:

A61K 31/498
A61K 9/127
A61P 25/28
A61P 25/00
A61P 3/10
A61P 37/00
A61P 1/04
A61P 37/06

US Classification:

424450, 514250

Abstract:

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

US Patent:

20110124649, May 26, 2011

Filed:

Nov 10, 2008

Appl. No.:

12/742208

Inventors:

Jun O. Liu - Clarksville MD, US
Xiaoyi Hu - San Diego CA, US
Xiaochun Chen - Baltimore MD, US
Dawei Ma - Shanghai, CN
Shridhar Bhat - Cockeysville MD, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

International Classification:

A61K 31/53
C07D 401/04
A61K 31/506
A61P 35/00
A61K 31/517
A61K 31/519

US Classification:

514245, 544328, 514256, 544284, 51426621, 51425217, 544249, 514267, 544212

Abstract:

Described herein are novel pyrimidine-pyridine compounds, methods of inhibiting methionine aminopeptidase and treating disorders (or symptoms thereof) associated with methionine aminopeptidase, wherein a compound of the invention is administered to a subject.

US Patent:

20110262517, Oct 27, 2011

Filed:

Apr 7, 2008

Appl. No.:

12/594777

Inventors:

Jun O. Liu - Clarksville MD, US
Curtis R. Chong - Honolulu HI, US
Jing Xu - Parkville MD, US
Jun Lu - Monmouth Junction NJ, US
Shridhar Bhat - Cockeysville MD, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

International Classification:

A61K 9/00
A61K 31/496
A61P 35/00
A61K 39/395
A61P 27/02
C12Q 1/26
A61K 31/4178

US Classification:

424423, 435 25, 51425407, 514397, 424427, 544366, 4241331

Abstract:

Described herein are methods of inhibiting angiogenesis, and treating or preventing a disease or disorder (or symptoms thereof) associated with angiogenesis, wherein an anti-angiogenesis compound is administered to a subject.