Jun Young Song

US Patent:

20080131940, Jun 5, 2008

Filed:

Jun 22, 2005

Appl. No.:

11/570423

Inventors:

Robert Chiu - Tustin CA, US
Jun Song - Los Angeles CA, US

International Classification:

C12P 19/34
C07H 21/02
C12N 15/63
C12N 5/00
C12N 15/87

US Classification:

435 913, 536 231, 4353201, 435325, 435463

Abstract:

The present invention provides nucleic acids that include a nucleotide sequence that encodes an siRNA, which nucleotide sequence is operably linked to a target cell-specific promoter RNA polymerase II promoter. The present invention further provides vectors, including expression vectors, which include a subject nucleic acid; and host cells that harbor a subject nucleic acid or a subject expression vector. The present invention further provides methods of modulating (e.g., reducing) expression of a gene in a target cell-specific manner, the methods generally involving introducing into a cell a subject expression vector.

US Patent:

20160313332, Oct 27, 2016

Filed:

Dec 17, 2014

Appl. No.:

15/104775

Inventors:

- Boston MA, US
Ralph Weissleder - Peabody MA, US
Kyungheon Lee - Cambridge MA, US
Jun Song - Somerville MA, US

International Classification:

G01N 33/574
B03C 1/30
B03C 1/033
G01N 21/64
G01N 15/14
G01N 1/40
G01N 33/50
B03C 1/08
B01L 3/00

Abstract:

In one aspect, a system for isolating particles includes a first array of magnets, a second array of magnets arranged generally in parallel with and spaced apart from the first array of magnets, and a micro fluidic device. The micro fluidic device includes a substrate, an inlet arranged on the substrate and configured to receive a fluid sample, an outlet arranged on the substrate, a first region of the substrate including a channel connected to the inlet, where the first region of the substrate is arranged to sandwich the channel between the first and second arrays of magnets.