Lin Liu

US Patent:

6773723, Aug 10, 2004

Filed:

Aug 30, 2000

Appl. No.:

09/652604

Inventors:

Robert C. Spiro - Half Moon Bay CA
Lin Shu Liu - Sunnyvale CA

Assignee:

Depuy Acromed, Inc. - Mountain View CA

International Classification:

A61K 31715

US Classification:

424488, 424 783, 424486, 4283166, 514 1, 514 2, 514 23, 530402

Abstract:

Disclosed are bilayer matrices of a polysaccharide such as collagen (COL) and another polysaccharide such as hyaluronic acid (HA) with various COL/HA ratios. Each layer has a porous structure. These materials are useful for tissue regeneration, particularly when used with orthopedic implants and drug delivery.

US Patent:

6896904, May 24, 2005

Filed:

Jun 14, 2004

Appl. No.:

10/868041

Inventors:

Robert C. Spiro - Half Moon Bay CA, US
Lin Shu Liu - Sunnyvale CA, US

Assignee:

Depuy Spine, Inc. - Raynham MA

International Classification:

A61K031/715
A61K038/16
A61K009/70
C08H001/02
B32B005/32

US Classification:

424488, 424 783, 424486, 4283166, 514 1, 514 2, 514 23, 530402

Abstract:

Disclosed are bilayer matrices of a polysaccharide such as collagen (COL) and another polysaccharide such as hyaluronic acid (HA) with various COL/HA ratios. Each layer has a porous structure. These materials are useful for tissue regeneration, particularly when used with orthopedic implants and drug delivery.

US Patent:

6936276, Aug 30, 2005

Filed:

Jun 14, 2004

Appl. No.:

10/868046

Inventors:

Robert C. Spiro - Half Moon Bay CA, US
Lin Shu Liu - Sunnyvale CA, US

Assignee:

Depuy Acromed, Inc. - Raynham MA

International Classification:

A61K031/715
A61K038/16
A61K009/70
C08H001/02
B32B005/32

US Classification:

424488, 424 783, 424486, 4283166, 514 1, 514 2, 514 23, 530402

Abstract:

Disclosed are bilayer matrices of a polysaccharide such as collagen (COL) and another polysaccharide such as hyaluronic acid (HA) with various COL/HA ratios. Each layer has a porous structure. These materials are useful for tissue regeneration, particularly when used with orthopedic implants and drug delivery.

US Patent:

6939562, Sep 6, 2005

Filed:

Jun 14, 2004

Appl. No.:

10/868043

Inventors:

Robert C. Spiro - Half Moon Bay CA, US
Lin Shu Liu - Sunnyvale CA, US

Assignee:

Depuy Acromed, Inc. - Raynham MA

International Classification:

A61K031/715
A61K038/16
A61K009/70
C08H001/02
B32B005/32

US Classification:

424488, 424 783, 424486, 4283166, 514 1, 514 2, 514 23, 530402

Abstract:

Disclosed are bilayer matrices of a polysaccharide such as collagen (COL) and another polysaccharide such as hyaluronic acid (HA) with various COL/HA ratios. Each layer has a porous structure. These materials are useful for tissue regeneration, particularly when used with orthopedic implants and drug delivery.

US Patent:

6953784, Oct 11, 2005

Filed:

Oct 3, 2003

Appl. No.:

10/679110

Inventors:

Andrea Y. Thompson - Mountain View CA, US
Lin Shu Liu - San Luis Obispo CA, US
Robert C. Spiro - Half Moon Bay CA, US

Assignee:

Depuy Spine, Inc. - Raynham MA

International Classification:

A61K031/738
C08B037/00

US Classification:

514 44, 514 54, 514 56, 536 21, 536 53, 536112

Abstract:

A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.

US Patent:

8392748, Mar 5, 2013

Filed:

Nov 3, 2009

Appl. No.:

12/611136

Inventors:

John A. Bocharov - Seattle WA, US
Geqiang (Sam) Zhang - Redmond WA, US
Krishna Prakash Duggaraju - Renton WA, US
Lin Liu - Sammamish WA, US
Jimin Gao - Seattle WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 11/00

US Classification:

714 411, 709217, 709231

Abstract:

A reliable streaming system increases reliability of live and on-demand streaming media events through a robust server architecture that allows fast failover and recovery in the event of network, hardware, or other failures. The system provides for failover of encoders, ingest servers, which receive encoded media data from encoders, and origin servers, which serve as the retrieval point of last resort for connecting clients. The system also provides a push proxy mechanism that allows one copy of data to feed redundant servers and pre-warm caches, saving on provisioned bandwidth. In addition, the system provides a distribution server role that allows content to be automatically syndicated to a region when needed. Thus, the reliable streaming system provides a streaming solution with no single point of failure and redundancy and fast failover built into the content network architecture.

US Patent:

8555163, Oct 8, 2013

Filed:

Jun 9, 2010

Appl. No.:

12/796670

Inventors:

Vishal Sood - Bothell WA, US
Geqiang (Sam) Zhang - Redmond WA, US
Lin Liu - Sammamish WA, US
Krishna Prakash Duggaraju - Renton WA, US
Sam J. George - Kenmore WA, US
Jack E. Freelander - Monroe WA, US
Anirban Roy - Kirkland WA, US
John A. Bocharov - Seattle WA, US
Jeffrey M. Wilcox - Seattle WA, US
Raymond Cheng - Sammamish WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 3/01
G06F 15/16

US Classification:

715704, 715716

Abstract:

A streaming abstraction system is described herein that provides application developers a client software development kit (SDK) on top of which to build smooth streaming solutions. The system reduces development time considerably and abstracts platform specific intricacies and protocol handling on the client. In addition, the streaming abstraction system makes it possible to monetize streaming content with advanced features like advertising and analytics and provides advanced capabilities like multiple camera angles, diagnostics, and error handling. In some embodiments, the streaming abstraction system provides an intermediate layer that operates between an application and an underlying client media platform. The intermediate layer manages smooth streaming protocol handling as well as interactions with the platform-specific runtime.

US Patent:

8621044, Dec 31, 2013

Filed:

Mar 16, 2009

Appl. No.:

12/405215

Inventors:

Vishal Sood - Bothell WA, US
Jack E. Freelander - Monroe WA, US
Anirban Roy - Kirkland WA, US
Lin Liu - Sammamish WA, US
Geqiang (Sam) Zhang - Redmond WA, US
Krishna Duggaraju - Renton WA, US
Sudheer Sirivara - Redmond WA, US
John A. Bocharov - Seattle WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 15/16
G06F 15/177

US Classification:

709219, 709217, 709220, 709222

Abstract:

An adaptive streaming system is described herein that provides a stateless connection between the client and server for streaming media playback in which the data is formatted in a manner that allows the client to make decisions and react more quickly to changing network conditions. The client requests uniform chunks of media from the server that include a portion of the media. The adaptive streaming system requests portions of a media file or of a live streaming event in small-sized chunks each having a distinguished URL. This allows streaming media data to be cached by existing Internet cache infrastructure. Each chunk contains metadata information that describes the encoding of the chunk and media content for playback by the client. The server may provide chunks in multiple encodings so that the client can switch quickly to chunks of a different bit rate or playback speed.