The present invention relates to a method of using a mammalian gene sequence and polypeptides encoded thereby to treat mammalian hematopoietic disorders. More specifically the present invention relates to methods of using compositions comprising at least one LP82 agonist, LP82 antagonist, LP82 polynucleotide, LP82 polypeptide, and/or LP82 antibody for the prevention and/or treatment of mammalian hematopoietic disorders, including, but not limited to, anemia, leukemia, and hematopoietic conditions caused by bone marrow transplantation or chemo-/radiation therapy.
Stanley Jaskunas - Indianapolis IN, US Ling Liu - Carmel IN, US Wei Zeng - Carmel IN, US
International Classification:
A61K038/17
US Classification:
514012000
Abstract:
The present invention relates to a method of using a mammalian gene sequence and polypeptides encoded thereby to treat mammalian hematopoietic disorders. More specifically the present invention relates to methods of using compositions comprising at least one resistin agonist, resistin polynucleotide and/or resistin polypeptide for the prevention and/or treatment of mammalian hematopoietic disorders, including, but not limited to, anemia, leukemia, and hematopoietic conditions caused by bone marrow transplantation or chemo-/radiation therapy.
Methods Of Using A Human Il-17 Related Polypeptide To Treat Disease
Andrew Glasebrook - Zionsville IN, US Ling Liu - Carmel IN, US Christy Love - Indianapolis IN, US Jonathan Tetreault - Indianapolis IN, US
Assignee:
ELI LILLY AND COMPANY - INDIANAPOLIS IN
International Classification:
A61K 38/20 C12N 15/24 C07H 21/04
US Classification:
424085200, 530351000, 536023500, 435320100
Abstract:
Methods are provided for the treatment or prevention of atherosclerosis, allergic autoimmune diseases, endothelial cell apoptosis, allograft vasculopathy, hypertension, congestive heart failure, ischemia/reperfusion injury, type 1 diabetes, inflammation, immunodeficiencies, cancers, and infectious diseases by administering a human IL-17 related polypeptide and/or an antibody recognizing an epitope thereof to a patient in need of such therapy.
- Indianapolis IN, US Philip Arthur HIPSKIND - New Palestine IN, US Renhua LI - Fishers IN, US Ling LIU - Carmel IN, US Takako WILSON - Indianapolis IN, US Aaron David WROBLESKI - Indianapolis IN, US
International Classification:
A61K 47/68 A61P 35/00
Abstract:
Provided are antibody-drug conjugates (ADCs) that bind to, and kill MET expressing tumor cells, and that are effective in treating MET expressing cancers. Also provided are novel compounds and methods of conjugating MET antibodies to generate such ADCs.
- Indianapolis IN, US Ling LIU - Carmel IN, US Jirong LU - Carmel IN, US Ying TANG - San Diego CA, US Jianghuai XU - San Diego CA, US
International Classification:
C07K 16/28 C07K 16/22 C07K 16/46
Abstract:
The present invention relates to compounds that bind to human vascular endothelial growth factor receptor-2 (VEGFR2) and human angiopoietin-2 (Ang2), and may be useful for treating cancer, especially solid tumors driven by VEGFR2 and Ang2, including gastric, hepatocellular carcinoma, ovarian, colorectal, non-small cell lung, biliary tract, and breast cancers.
- Indianapolis IN, US Ling Liu - Carmel IN, US Jirong Lu - Carmel IN, US Ying Tang - San Diego CA, US Jianghuai Xu - San Diego CA, US
International Classification:
C07K 16/22 C07K 16/40 C07K 16/28
Abstract:
The present invention relates to compounds that bind to human vascular endothelial growth factor receptor-2 (VEGFR2) and human angiopoietin-2 (Ang2), and may be useful for treating cancer, especially solid tumors driven by VEGFR2 and Ang2, including gastric, hepatocellular carcinoma, ovarian, colorectal, non-small cell lung, biliary tract, and breast cancers.
UtrechtSenior Programmer at Accenture Technology Solution... Experienced in EAI middleware development and implementation, certified in TIBCO BusinessWorks5.2,familiar with WebMethods, SonicMQ, WebSphere.
At Cacharel, where the Chinese duo Ling Liu and Dawei Sun were showing their second collection, the focus was on coats, warm outfits in wool or felt, and sensual knit dresses that wrapped up around the neck.