The present invention relates to a method of using a mammalian gene sequence and polypeptides encoded thereby to treat mammalian hematopoietic disorders. More specifically the present invention relates to methods of using compositions comprising at least one LP82 agonist, LP82 antagonist, LP82 polynucleotide, LP82 polypeptide, and/or LP82 antibody for the prevention and/or treatment of mammalian hematopoietic disorders, including, but not limited to, anemia, leukemia, and hematopoietic conditions caused by bone marrow transplantation or chemo-/radiation therapy.
Barrett Allan - Encinitas CA, US Chi-Kin Chow - Brownsburg IN, US Ling Liu - Carmel IN, US Jirong Lu - Carmel IN, US Jonathan Wendell Tetreault - Indianapolis IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07K 16/24
US Classification:
5303873, 53038823
Abstract:
Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.
Barrett Allan - Encinitas CA, US Chi-Kin Chow - Brownsburg IN, US Ling Liu - Carmel IN, US Jirong Lu - Carmel IN, US Jonathan Wendell Tetreault - Indianapolis IN, US Ying Tang - San Diego CA, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 39/395 C07K 16/24
US Classification:
4241451, 4241331, 4241581, 5303873, 53038823
Abstract:
Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.
Fibroblast Growth Factor Receptor-3 (Fgfr-3) Inhibitors And Methods Of Treatment
Haijun Sun - New York NY, US Ling Liu - Carmel IN, US
Assignee:
ImClone, LLC - New York NY
International Classification:
A61K 39/395 C07K 16/28 C07K 16/00
US Classification:
4241431, 4241391, 5303879, 53038822
Abstract:
The present invention relates to an isolated antibody or fragment thereof, which specifically binds to human FGFR-3(IIIb) and FGFR-3(IIIc), or mutant forms thereof. Further embodiments include pharmaceutical compositions comprising the antibody and methods of using the antibody to treat cancer.
Julian Davies - La Jolla CA, US Ling Liu - Carmel IN, US Jirong Lu - Carmel IN, US Peter Edward Vaillancourt - Del Mar CA, US Mark Andrew Wortinger - Greenwood IN, US Wei Zeng - Carmel IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07K 16/00
US Classification:
5303871, 5303888
Abstract:
Provided are monoclonal antibodies, antigen-binding fragments thereof, and combinations of the foregoing, that bind to, and inhibit the activity of, c-Met, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by c-Met.
Julian Davies - La Jolla CA, US Ling Liu - Carmel IN, US Jirong Lu - Carmel IN, US Peter Edward Vaillancourt - Del Mar CA, US Mark Andrew Wortinger - Greenwood IN, US Wei Zeng - Carmel IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 39/395
US Classification:
4241301, 4241411, 4241431, 4241551
Abstract:
Provided are monoclonal antibodies, antigen-binding fragments thereof, and combinations of the foregoing, that bind to, and inhibit the activity of, c-Met, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by c-Met.
Fibroblast Growth Factor Receptor-3 (Fgfr-3) Inhibitors And Methods Of Treatment
Haijun Sun - New York NY, US Ling Liu - Carmel IN, US
Assignee:
ImClone, LLC - New York NY
International Classification:
A61K 39/395 C07K 16/28 C07K 16/00
US Classification:
4241431, 4241391, 5303879, 53038822
Abstract:
The present invention relates to an isolated antibody or fragment thereof, which specifically binds to human FGFR-3(IIIb) and FGFR-3(IIIc), or mutant forms thereof. Further embodiments include pharmaceutical compositions comprising the antibody and methods of using the antibody to treat cancer.
Stanley Jaskunas - Indianapolis IN, US Ling Liu - Carmel IN, US Wei Zeng - Carmel IN, US
International Classification:
A61K038/17
US Classification:
514012000
Abstract:
The present invention relates to a method of using a mammalian gene sequence and polypeptides encoded thereby to treat mammalian hematopoietic disorders. More specifically the present invention relates to methods of using compositions comprising at least one resistin agonist, resistin polynucleotide and/or resistin polypeptide for the prevention and/or treatment of mammalian hematopoietic disorders, including, but not limited to, anemia, leukemia, and hematopoietic conditions caused by bone marrow transplantation or chemo-/radiation therapy.
UtrechtSenior Programmer at Accenture Technology Solution... Experienced in EAI middleware development and implementation, certified in TIBCO BusinessWorks5.2,familiar with WebMethods, SonicMQ, WebSphere.
At Cacharel, where the Chinese duo Ling Liu and Dawei Sun were showing their second collection, the focus was on coats, warm outfits in wool or felt, and sensual knit dresses that wrapped up around the neck.
Date: Mar 04, 2012
Category: Entertainment
Source: Google
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