Linh Ba Le

US Patent:

7696083, Apr 13, 2010

Filed:

Mar 10, 2006

Appl. No.:

11/373520

Inventors:

Tom Kwa - San Jose CA, US
Linh Le - San Jose CA, US
Nina Tikhomirova - San Jose CA, US

Assignee:

Endeoco Corporation - San Juan Capistrano CA

International Classification:

H01L 21/4763

US Classification:

438622, 257E21122

Abstract:

A multi-layer device is provided for connecting to an electrical unit enclosed within the multi-layer device. A first wafer has a first outer terminal and a second outer terminal with etch pits. A first insulator has a first surface bonded to the first wafer and a first inner terminal located on an opposing second surface. A second wafer has a first surface bonded to the second surface of the first insulating layer and includes a pillar electrically connected to the first wafer. A second insulator has a first surface bonded to a second surface of the second wafer and a second inner terminal located on the first surface of the second insulator. The first outer terminal is electrically connected to the first inner terminal, and the second outer terminal is electrically connected to the second inner terminal. The first and second outer terminals are adapted for connecting to an electrical unit. A reinforcement is positioned adjacent to at least one of the first and second outer and, inner terminals to provide for reinforcement of the at least one of the first and second outer and inner terminals.

US Patent:

8546108, Oct 1, 2013

Filed:

Jan 24, 2011

Appl. No.:

13/575222

Inventors:

Sanjiv Ghanshani - Irvine CA, US
Linh Q. Le - Tustin CA, US
Yi Liu - Irvine CA, US
Lance E. Steward - Irvine CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

C12N 9/52

US Classification:

435 711, 435 691, 435220, 435471

Abstract:

The present specification discloses expression constructs comprising single-chain proteins comprising a di-chain loop region comprising an exogenous protease cleavage site and a protease that can cleave the exogenous protease cleavage site located within the di-chain loop, cell compositions comprising such expression construct, and intracellular methods of converting the single-chain protein into its di-chain form.

US Patent:

20110189162, Aug 4, 2011

Filed:

Dec 16, 2010

Appl. No.:

12/970239

Inventors:

Sanjiv Ghanshani - Irvine CA, US
Linh Q. Le - Tustin CA, US
Yi Liu - Irvine CA, US
Lance E. Steward - Irvine CA, US

Assignee:

ALLERGAN, INC. - Irvine CA

International Classification:

A61K 38/48
C07H 21/00
A61K 8/66
A61Q 19/08
A61P 29/00
C12N 15/63
C12N 9/52

US Classification:

424 9467, 536 232, 4353201, 435220

Abstract:

The present specification discloses modified Clostridial toxins, compositions comprising an integrated protease cleavage site-binding domain, polynucleotide molecules encoding such modified Clostridial toxins and compositions comprising di-chain forms of such modified Clostridial toxins.

US Patent:

20140030759, Jan 30, 2014

Filed:

Sep 26, 2013

Appl. No.:

14/038328

Inventors:

Linh Q. Le - Tustin CA, US
Yi Liu - Irvine CA, US
Lance E. Steward - Irvine CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

C12P 21/00

US Classification:

435 681

Abstract:

The present specification discloses expression constructs comprising single-chain proteins comprising a di-chain loop region comprising an exogenous protease cleavage site and a protease that can cleave the exogenous protease cleavage site located within the di-chain loop, cell compositions comprising such expression construct, and intracellular methods of converting the single-chain protein into its di-chain form.

US Patent:

48261106, May 2, 1989

Filed:

Jun 22, 1987

Appl. No.:

7/064423

Inventors:

Linh T. Le - Seattle WA

Assignee:

The Boeing Company - Seattle WA

International Classification:

B64C 1316

US Classification:

244194

Abstract:

Prevention of actuator oscillation due to failure mode in an aircraft pitch axis control system is provided by an oscillatory failure monitor. The oscillatory failure monitor provides power shutdown of the actuator through inner loop modeling and error signal processing of inner loop disturbances.

US Patent:

20210162027, Jun 3, 2021

Filed:

Feb 3, 2021

Appl. No.:

17/166386

Inventors:

- Irvine CA, US
Joanne Wang - Irvine CA, US
Yi Liu - Irvine CA, US
Amy Brideau-Andersen - San Clemente CA, US
Lance E. Steward - Irvine CA, US
Linh Q. Le - Tustin CA, US
Edward C. Hsia - Irvine CA, US

International Classification:

A61K 38/48
A61K 8/99
A61Q 19/02
A61P 17/00
A61K 9/00

Abstract:

Methods for treating melanin-related afflictions of the skin, such as hyperpigmentation, are provided. The methods comprise administering a composition comprising BoNT/DC.

US Patent:

20180344820, Dec 6, 2018

Filed:

May 30, 2018

Appl. No.:

15/992627

Inventors:

- Irvine CA, US
Joanne Wang - Irvine CA, US
Yi Liu - Irvine CA, US
Amy Brideau-Andersen - San Clemente CA, US
Lance E. Steward - Irvine CA, US
Linh Q. Le - Tustin CA, US
Edward C. Hsai - Irvine CA, US

International Classification:

A61K 38/48
A61K 9/00
A61P 17/00

Abstract:

Methods for treating melanin-related afflictions of the skin, such as hyperpigmentation, are provided. The methods comprise administering a composition comprising BoNT/DC.

US Patent:

20160319265, Nov 3, 2016

Filed:

May 16, 2016

Appl. No.:

15/155302

Inventors:

- Irvine CA, US
Linh Q. Le - Tustin CA, US
Yi Liu - Irvine CA, US
Lance E. Steward - Irvine CA, US

International Classification:

C12N 9/52
C12N 9/50
C12N 15/70
C12P 21/06
C07K 14/33

Abstract:

The present specification discloses expression constructs comprising single-chain proteins comprising a di-chain loop region comprising an exogenous protease cleavage site and a protease that can cleave the exogenous protease cleavage site located within the di-chain loop, cell compositions comprising such expression construct, and intracellular methods of converting the single-chain protein into its di-chain form.