Lu Liu

US Patent:

6670168, Dec 30, 2003

Filed:

Oct 30, 2000

Appl. No.:

09/702029

Inventors:

Leonard Katz - Oakland CA
Lu Liu - Redwood City CA
Loleta M. Chung - San Francisco CA

Assignee:

Kosan Bioscience, Inc. - Hayward CA

International Classification:

C12N 120

US Classification:

43525235

Abstract:

Recombinant host cells that produce rapamycin analogues are constructed by deleting or modifying rapamycin biosynthetic gene cluster genes and are useful in the production of compounds used as antifungals, anticancers, immunosuppressants, and neurotrophins.

US Patent:

7314975, Jan 1, 2008

Filed:

Aug 22, 2006

Appl. No.:

11/507729

Inventors:

Itzhak Kurek - San Francisco CA, US
Lu Liu - Palo Alto CA, US
Genhai Zhu - San Jose CA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

A01H 1/00
C07K 14/415
C07H 21/04
C12N 15/29
C12N 15/52

US Classification:

800289, 435 6, 435 691, 435468, 435419, 4352523, 4353201, 435183, 530370, 536 236, 800278, 800295

Abstract:

The present invention provides thermostable polypeptides related to Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.

US Patent:

7557267, Jul 7, 2009

Filed:

Oct 5, 2007

Appl. No.:

11/867723

Inventors:

Itzhak Kurek - San Francisco CA, US
Lu Liu - Palo Alto CA, US
Genhai Zhu - San Jose CA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

C12N 15/05
A01H 1/00
C07H 21/04
C07K 14/415
C12N 15/29

US Classification:

800295, 435468, 4353201, 435419, 530370, 536 236, 800278, 800289

Abstract:

The present invention provides thermostable polypeptides related to Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.

US Patent:

7723573, May 25, 2010

Filed:

May 29, 2009

Appl. No.:

12/474298

Inventors:

Itzhak Kurek - San Francisco CA, US
Lu Liu - Palo Alto CA, US
Genhai Zhu - San Jose CA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

C12N 15/05
A01H 1/00
C07H 21/04
C07K 14/415
C12N 15/29

US Classification:

800295, 435183, 435468, 4353201, 435419, 530370, 536 232, 536 236, 800278, 800289

Abstract:

The present invention provides thermostable polypeptides related to Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.

US Patent:

8110113, Feb 7, 2012

Filed:

Apr 28, 2008

Appl. No.:

12/110776

Inventors:

Itzhak Kurek - San Francisco CA, US
Xuehua Hu - Foster City CA, US
Genhai Zhu - San Jose CA, US
Lu Liu - Palo Alto CA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

B01D 15/36

US Classification:

210659, 436 63, 436161, 436173

Abstract:

The present invention provides a method for determining a level of a RuBP, PGA, 2-PA in a photosynthetic cellular extract by resolving at least one RuBP, PGA, or 2-PA or combinations thereof in a photosynthetic cellular extract obtained from a plant. In another aspect, it provides for detecting at least one resolved RuBP, PGA, or 2-PA or combinations, thereby determining a level of the resolved RuBP, PGA, or 2-PA or combinations. In one aspect the photosynthetic cellular extract is obtained from a plant subjected to an abiotic stress. A method of the invention can be useful, for example, for identifying plants with increased photosynthetic performance. Also included herein is a high throughput system for identifying a plant with increased photosynthetic performance.

US Patent:

8129512, Mar 6, 2012

Filed:

Apr 14, 2008

Appl. No.:

12/102639

Inventors:

Genhai Zhu - San Jose CA, US
Itzhak Kurek - San Francisco CA, US
Lu Liu - Palo Alto CA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

C12N 15/29
C12N 15/52
C12N 15/82
A01H 5/00
A01H 5/10

US Classification:

536 236, 4352572, 4353201, 435419, 800284

Abstract:

Methods for identifying one or more amino acid substitutions in a Rubisco large subunit polypeptide (variant) that confer increased Rubisco activity in a unicellular photosynthetic organism and transferring those substitutions to a Rubisco large subunit polypeptide of a higher plant cell are described herein. Methods and compositions for modulating plant productivity using the modified Rubisco large subunit polypeptide variants are provided. The Rubisco large subunit sequences are used in a variety of methods including increasing plant productivity in a plant. Transformed plants, plant cell, tissues, seed, and expression vectors are also provided.

US Patent:

8546648, Oct 1, 2013

Filed:

Sep 18, 2012

Appl. No.:

13/621895

Inventors:

Lu Liu - Palo Alto CA, US
Genhai Zhu - San Jose CA, US

Assignee:

Pioneer Hi Bred International Inc - Johnston IA

International Classification:

A01H 1/00
C12N 15/00
C07H 21/04
C07K 14/415
C12N 15/29
C12N 15/52
C12N 15/63

US Classification:

800295, 435 618, 435468, 435183, 435419, 4353201, 530370, 536 232, 536 236, 800278

Abstract:

The present invention provides thermostable polypeptides related to Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.

US Patent:

8592649, Nov 26, 2013

Filed:

Aug 20, 2010

Appl. No.:

12/860265

Inventors:

Lu Liu - Palo Alto CA, US
Hoa Giang - Oakland CA, US
Dale F. Loussaert - Clive IA, US
Haiyin Wang - Johnston IA, US

Assignee:

Pioneer Hi Bred International Inc - Johnston IA

International Classification:

A01H 5/00
C12N 15/82
C12N 5/04
C07H 21/04

US Classification:

800298, 800278, 800306, 800312, 800320, 435419, 536 2374

Abstract:

The present invention provides methods and compositions relating to altering NT activity, nitrogen utilization efficiency and/or uptake in plants. The invention relates to a method for the production of plants with maintained or increased yield under low nitrogen fertility. The invention provides isolated nitrate transporter variant (NT variant) nucleic acids and their encoded proteins. The invention further provides recombinant expression cassettes, host cells, and transgenic plants. Plants transformed with nucleotide sequences encoding the NT variant enzyme show improved properties, for example, increased yield.